| Literature DB >> 32343005 |
Katie Harron1, Maximiliane Verfuerden1, Ibinabo Ibiebele2, Can Liu3, Alex Kopp4, Astrid Guttmann4, Jane Ford2, Jan van der Meulen5, Anders Hjern3, Ruth Gilbert1.
Abstract
BACKGROUND: Young maternal age is associated with lower birthweight and higher rates of preterm birth and childhood hospitalisations. Internationally, teen pregnancy rates vary widely, reflecting differences in social, welfare, and health care factors in different cultural contexts.Entities:
Keywords: adolescence; hospitalisation; infant; infant mortality; maternal age; newborn; preterm delivery
Mesh:
Year: 2020 PMID: 32343005 PMCID: PMC8425326 DOI: 10.1111/ppe.12685
Source DB: PubMed Journal: Paediatr Perinat Epidemiol ISSN: 0269-5022 Impact factor: 3.103
Study population characteristics: infants born ≥24 wk gestation between 2010 and 2014 (2008‐2012 for Sweden) and surviving to postnatal discharge
|
Scotland N = 173 316 No. (%) |
England N = 1 812 784 No. (%) |
NSW N = 231 306 No. (%) |
Ontario N = 472 151 No. (%) |
Sweden N = 313 192 No. (%) | |
|---|---|---|---|---|---|
| Maternal age (y) | |||||
| 15‐19 | 12 123 (7.1) | 109 990 (6.1) | 8839 (3.8) | 17 797 (3.8) | 6058 (1.9) |
| 20‐24 | 39 005 (22.7) | 414 800 (22.9) | 37 559 (16.2) | 73 387 (15.5) | 53 084 (16.9) |
| 25‐29 | 59 281 (34.3) | 631 949 (34.9) | 81 812 (35.4) | 168 442 (35.7) | 116 138 (37.1) |
| 30‐34 | 62 907 (35.9) | 656 045 (36.2) | 103 096 (44.6) | 212 525 (45.0) | 137 912 (44.0) |
| Quintile of deprivation | |||||
| Most deprived | 44 536 (26.0) | 549 232 (30.3) | 49 381 (21.3) | 110 916 (23.5) | 62 631 (20.0) |
| 2 | 37 955 (21.9) | 416 681 (23.0) | 32 275 (14.0) | 98 656 (20.9) | 62 663 (20.0) |
| 3 | 34 961 (19.7) | 329 807 (18.2) | 45 737 (19.8) | 96 585 (20.5) | 62 586 (20.0) |
| 4 | 29 040 (16.7) | 273 082 (15.1) | 42 966 (18.6) | 96 540 (20.4) | 62 669 (20.0) |
| Most affluent | 26 797 (15.6) | 243 982 (13.5) | 60 947 (26.3) | 69 454 (14.7) | 62 643 (20.0) |
| Gestational age (wk) | |||||
| 24‐27 | 265 (0.1) | 2968 (0.2) | 351 (0.2) | 836 (0.2) | 250 (0.1) |
| 28‐31 | 987 (0.5) | 8980 (0.5) | 934 (0.4) | 2076 (0.4) | 632 (0.2) |
| 32‐33 | 1093 (0.6) | 11 560 (0.6) | 1372 (0.6) | 2835 (0.6) | 922 (0.3) |
| 34‐36 | 6905 (4.0) | 72 021 (4.0) | 9418 (4.1) | 21 104 (4.5) | 8916 (2.8) |
| 37‐38 | 28 047 (16.3) | 315 477 (17.4) | 54 623 (23.6) | 119 697 (25.4) | 55 987 (17.9) |
| ≥39 | 136 019 (78.5) | 1 401 778 (77.3) | 164 608 (71.2) | 325 603 (69.0) | 246 485 (78.7) |
Quintiles are based on the whole population except for Sweden, where quintiles are based on the study population.
Figure 1Percentage of mothers in most deprived and most affluent quintiles* by maternal age and country. *Quintiles are based on whole population except for Sweden, where quintiles are based on the study population
Figure 2Rates of preterm births*, unplanned hospital admission, emergency department visits, and mortality within 12 mo of postnatal discharge, by maternal age and country. Error bars are 95% confidence intervals. *The preterm birth rate denominator is survivors to discharge home. **ED data were not available in this study for Scotland. ***Cell sizes <10 were suppressed
Figure 3Risk ratios for preterm birth (Preterm birth rate denominator is survivors to discharge home), unplanned admissions, and ED visits. Mothers aged 30‐34 y serve as the reference group. Dashed line indicates no difference. Risk ratios for mortality are provided in Figure S1
Risk differences and risk ratios for preterm births, mortality, unplanned admissions, and ED visits within 12 mo of postnatal discharge, comparing mothers aged 15‐19 y with mothers aged 30‐34 y
| Absolute risk N (N per 100 infants or per 10 000 for mortality); all ages | Risk difference per 100 infants or per 10 000 for mortality (95% CI) | Risk ratio (95% CI) | |
|---|---|---|---|
| Preterm birth (<37 wk) | |||
| Scotland | 9250 (5.3) | 1.3 (0.9, 1.8) | 1.26 (1.17, 1.36) |
| England | 25 529 (5.3) | 1.3 (1.2, 1.5) | 1.26 (1.23, 1.29) |
| NSW | 12 075 (5.2) | 2.0 (1.4, 2.5) | 1.39 (1.28, 1.51) |
| Ontario | 26 851 (5.7) | 1.5 (1.1, 1.8) | 1.26 (1.19, 1.33) |
| Sweden | 10 720 (3.4) | 1.2 (0.7, 1.7) | 1.37 (1.21, 1.55) |
| Mortality | |||
| Scotland | 247 (14.3) | 19.7 (8.7, 30.6) | 2.47 (1.69, 3.61) |
| England | 1831 (10.1) | 9.8 (7.2, 12.4) | 2.21 (1.88, 2.61) |
| NSW | — | — | — |
| Ontario | 389 (8.2) | 16.7 (9.7, 23.8) | 3.92 (2.74, 5.60) |
| Sweden | 163 (5.2) | 12.7 (2.5, 23.0) | 4.38 (2.23, 8.61) |
| % of infants with ≥1 unplanned admission | |||
| Scotland | 31 577 (18.2) | 7.0 (6.2, 7.8) | 1.44 (1.38, 1.50) |
| England | 355 574 (19.6) | 9.1 (8.8, 9.4) | 1.53 (1.51, 1.55) |
| NSW | 34 562 (14.9) | 7.6 (6.7, 8.5) | 1.56 (1.49, 1.64) |
| Ontario | 39 521 (8.4) | 3.4 (2.9, 3.9) | 1.44 (1.37, 1.50) |
| Sweden | 33 560 (10.7) | 3.7 (2.8, 4.5) | 1.37 (1.28, 1.47) |
| % of infants with ≥1 ED visit | |||
| Scotland | — | — | — |
| England | 681 708 (37.6) | 16.0 (15.7, 16.4) | 1.48 (1.47, 1.50) |
| NSW | 157 822 (68.2) | 7.1 (6.1, 8.0) | 1.11 (1.08, 1.13) |
| Ontario | 207 221 (43.9) | 26.2 (25.5, 26.9) | 1.69 (1.65, 1.72) |
| Sweden | 116 645 (37.2) | 9.5 (8.2, 10.7) | 1.27 (1.22, 1.32) |
| % of infants with ≥1 hospital contact (unplanned admission, ED visit or mortality) | |||
| Scotland | — | — | — |
| England | 779 824 (43.0) | 16.2 (15.8, 16.5) | 1.42 (1.41, 1.43) |
| NSW | 160 029 (69.2) | 6.4 (5.5, 7.4) | 1.09 (1.07, 1.12) |
| Ontario | 212 786 (45.1) | 25.4 (24.7, 26.1) | 1.64 (1.61, 1.67) |
| Sweden | 127 424 (40.7) | 9.8 (8.5, 11.0) | 1.25 (1.21, 1.30) |
The denominator for preterm births was survivors to discharge home.
Cell sizes <10 were suppressed.
ED data were not available in this study for Scotland.
Figure 4Risk differences for preterm birth (Preterm birth rate denominator is survivors to discharge home), unplanned admissions, and ED visits. Mothers aged 30‐34 y serve as the reference group. Dashed line indicates no difference