| Literature DB >> 3234225 |
E Pawlicka1, E Bańkowski, L Chrostek, M Szmitkowski.
Abstract
Treatment of rats with 10% ethanol for 6 months induced a 3-4-fold increase of [3H]proline incorporation into liver collagen and enhanced the level of prolyl hydroxylase activity in liver and serum of intoxicated rats. Several diagnostic tests used to assess liver disease failed to demonstrate any symptom of liver damage. Therefore, increased collagen biosynthesis appears to precede other symptoms of liver damage induced by ethanol.Entities:
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Year: 1988 PMID： 3234225 DOI： 10.1016/0376-8716(88)90045-2
Source DB: PubMed Journal: Drug Alcohol Depend ISSN： 0376-8716 Impact factor: 4.492