John M Daniel1, Lesley N Davidson2, Jennifer R Havens3, John A Bauer4, Lori A Shook4. 1. Clinical Assistant Professor of Pediatrics, Children's Mercy Hospitals and Clinics, Kansas City, Missouri; University of Missouri-Kansas City, School of Medicine, Kansas City, Missouri. 2. Neonatologist, Pediatrix Medical Group of Kentucky, PSC, Lexington, Kentucky. 3. Associate Professor of Behavioral Science, Department of Behavioral Science, College of Medicine, University of Kentucky, Lexington, Kentucky; Center on Drug and Alcohol Research, College of Medicine, University of Kentucky, Lexington, Kentucky. 4. Professor of Pediatrics, Division of Neonatology, College of Medicine, Kentucky Children's Hospital, University of Kentucky, Lexington, Kentucky.
Abstract
OBJECTIVE: To determine if aromatherapy added to the current standard of care for opioid withdrawal syndrome decreases hospitali-zation and need for opioid replacement in neonates. DESIGN: Nonblinded, randomized control trial. SETTING: Level 4 neonatal intensive care unit (NICU). PATIENTS AND PARTICIPANTS: Thirty eight patients met inclusion criteria of greater than or equal to 36 weeks of gestation, history of in-trauterine opioid exposure, primary diagnosis of neonatal abstinence syndrome (NAS), and parental permission to participate. INTERVENTIONS: Infants were randomized to either a standard therapy group or a standard therapy plus aromatherapy. MAIN OUTCOME MEASURE(S): Duration of therapy and length of stay. RESULTS: Our pilot study showed that the use of aromatherapy in conjunction with standard therapy reduced the duration of medica-tion treatment by 41 percent and hospital length of stay in the NICU by 36 percent. CONCLUSIONS: The use of aromatherapy appears to help mitigate symptoms of NAS and offers to be a viable treatment modality when used with conventional therapy.
RCT Entities:
OBJECTIVE: To determine if aromatherapy added to the current standard of care for opioid withdrawal syndrome decreases hospitali-zation and need for opioid replacement in neonates. DESIGN: Nonblinded, randomized control trial. SETTING: Level 4 neonatal intensive care unit (NICU). PATIENTS AND PARTICIPANTS: Thirty eight patients met inclusion criteria of greater than or equal to 36 weeks of gestation, history of in-trauterine opioid exposure, primary diagnosis of neonatal abstinence syndrome (NAS), and parental permission to participate. INTERVENTIONS:Infants were randomized to either a standard therapy group or a standard therapy plus aromatherapy. MAIN OUTCOME MEASURE(S): Duration of therapy and length of stay. RESULTS: Our pilot study showed that the use of aromatherapy in conjunction with standard therapy reduced the duration of medica-tion treatment by 41 percent and hospital length of stay in the NICU by 36 percent. CONCLUSIONS: The use of aromatherapy appears to help mitigate symptoms of NAS and offers to be a viable treatment modality when used with conventional therapy.
Authors: Roberta Esteves Vieira de Castro; Miguel Rodríguez-Rubio; Maria Clara de Magalhães-Barbosa; Arnaldo Prata-Barbosa Journal: Rev Bras Ter Intensiva Date: 2022-01-24