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Literature DB >> 32327587

Calcium as a biased cofactor.

Madhu Chaturvedi¹, Arun K Shukla².

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2020 PMID： 32327587 PMCID： PMC7115873 DOI： 10.1126/science.abb4393

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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15 in total

Review 1. Emerging Approaches to GPCR Ligand Screening for Drug Discovery.

Authors: Punita Kumari; Eshan Ghosh; Arun K Shukla
Journal: Trends Mol Med Date: 2015-10-16 Impact factor: 11.951

2. Determination of the melanocortin-4 receptor structure identifies Ca²⁺ as a cofactor for ligand binding.

Authors: Jing Yu; Luis E Gimenez; Ciria C Hernandez; Yiran Wu; Ariel H Wein; Gye Won Han; Kyle McClary; Sanraj R Mittal; Kylie Burdsall; Benjamin Stauch; Lijie Wu; Sophia N Stevens; Alys Peisley; Savannah Y Williams; Valerie Chen; Glenn L Millhauser; Suwen Zhao; Roger D Cone; Raymond C Stevens
Journal: Science Date: 2020-04-24 Impact factor: 47.728

Review 3. Methodological advances: the unsung heroes of the GPCR structural revolution.

Authors: Eshan Ghosh; Punita Kumari; Deepika Jaiman; Arun K Shukla
Journal: Nat Rev Mol Cell Biol Date: 2015-01-15 Impact factor: 94.444

Review 4. New Binding Sites, New Opportunities for GPCR Drug Discovery.

Authors: H C Stephen Chan; Yi Li; Thamani Dahoun; Horst Vogel; Shuguang Yuan
Journal: Trends Biochem Sci Date: 2019-01-03 Impact factor: 13.807

Review 5. Harnessing Ion-Binding Sites for GPCR Pharmacology.

Authors: Barbara Zarzycka; Saheem A Zaidi; Bryan L Roth; Vsevolod Katritch
Journal: Pharmacol Rev Date: 2019-10 Impact factor: 25.468

6. The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology.

Authors: Ya-Xiong Tao
Journal: Endocr Rev Date: 2010-02-26 Impact factor: 19.871

Review 7. Melanocortin-4 Receptor Signalling: Importance for Weight Regulation and Obesity Treatment.

Authors: Peter Kühnen; Heiko Krude; Heike Biebermann
Journal: Trends Mol Med Date: 2019-01-11 Impact factor: 11.951

Review 8. 60 YEARS OF POMC: Regulation of feeding and energy homeostasis by α-MSH.

Authors: Erica J P Anderson; Isin Çakir; Sheridan J Carrington; Roger D Cone; Masoud Ghamari-Langroudi; Taneisha Gillyard; Luis E Gimenez; Michael J Litt
Journal: J Mol Endocrinol Date: 2016-03-03 Impact factor: 5.098

Review 9. Mechanisms of signalling and biased agonism in G protein-coupled receptors.

Authors: Denise Wootten; Arthur Christopoulos; Maria Marti-Solano; M Madan Babu; Patrick M Sexton
Journal: Nat Rev Mol Cell Biol Date: 2018-10 Impact factor: 94.444

10. Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity.

Authors: Luca A Lotta; Jacek Mokrosiński; Edson Mendes de Oliveira; Chen Li; Stephen J Sharp; Jian'an Luan; Bas Brouwers; Vikram Ayinampudi; Nicholas Bowker; Nicola Kerrison; Vasileios Kaimakis; Diana Hoult; Isobel D Stewart; Eleanor Wheeler; Felix R Day; John R B Perry; Claudia Langenberg; Nicholas J Wareham; I Sadaf Farooqi
Journal: Cell Date: 2019-04-18 Impact factor: 41.582

1 in total

Review 1. Melanocortin-4 receptor complexity in energy homeostasis,obesity and drug development strategies.

Authors: Munazza Tamkeen Fatima; Ikhlak Ahmed; Khalid Adnan Fakhro; Ammira Sarah Al-Shabeeb Akil
Journal: Diabetes Obes Metab Date: 2022-01-11 Impact factor: 6.408