Literature DB >> 32323378

Obesity and Alzheimer's disease: Molecular bases.

Pasquale Picone1, Marta Di Carlo1, Domenico Nuzzo1.   

Abstract

Obesity is a complex, chronic, and multifactorial condition characterized by abnormal fat accumulation in tissues and organs and inducing negative effects on human health. Alzheimer's disease is a progressive and irreversible neurodegenerative disease, associated with amyloid plaques and neurofibrillary tangles in the brain. The correlation between obesity and Alzheimer's disease has been discovered, but the molecules and molecular mechanisms linking these conditions are not yet fully elucidated. In this review, we focused on the most important processes linking the fat accumulation and the alterations of the brain structure and functions.
© 2020 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

Entities:  

Keywords:  Alzheimer's disease; molecular mechanisms; obesity

Mesh：

Substances：

Year:  2020        PMID： 32323378     DOI： 10.1111/ejn.14758

Source DB:  PubMed          Journal:  Eur J Neurosci        ISSN： 0953-816X            Impact factor:   3.386


  9 in total

Review 1.  Particulate matter and Alzheimer's disease: an intimate connection.

Authors:  Devin R O'Piela; George R Durisek; Yael-Natalie H Escobar; Amy R Mackos; Loren E Wold
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Review 2.  The Endocrine Adipose Organ: A System Playing a Central Role in COVID-19.

Authors:  Francesca Cinti; Saverio Cinti
Journal:  Cells       Date:  2022-07-04       Impact factor: 7.666

Review 3.  A Narrative Review of the Effects of Citrus Peels and Extracts on Human Brain Health and Metabolism.

Authors:  Kentaro Matsuzaki; Akira Nakajima; Yuanqiang Guo; Yasushi Ohizumi
Journal:  Nutrients       Date:  2022-04-28       Impact factor: 6.706

4.  Anti-Obesity Effect of Pine Needle Extract on High-Fat Diet-Induced Obese Mice.

Authors:  Eun A Kim; Ju-Hwan Yang; Eun-Hye Byeon; Woong Kim; Dawon Kang; Jaehee Han; Seong-Geun Hong; Deok-Ryong Kim; Sang-Je Park; Jae-Won Huh; Hyeonsook Cheong; Seung-Pil Yun; Dong-Kun Lee
Journal:  Plants (Basel)       Date:  2021-04-21

Review 5.  Beneficial Effects of Citrus-Derived Polymethoxylated Flavones for Central Nervous System Disorders.

Authors:  Kentaro Matsuzaki; Yasushi Ohizumi
Journal:  Nutrients       Date:  2021-01-04       Impact factor: 5.717

Review 6.  Crosstalk between Gut and Brain in Alzheimer's Disease: The Role of Gut Microbiota Modulation Strategies.

Authors:  Umair Shabbir; Muhammad Sajid Arshad; Aysha Sameen; Deog-Hwan Oh
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7.  New Neuroprotective Effect of Lemon IntegroPectin on Neuronal Cellular Model.

Authors:  Domenico Nuzzo; Pasquale Picone; Costanza Giardina; Miriana Scordino; Giuseppa Mudò; Mario Pagliaro; Antonino Scurria; Francesco Meneguzzo; Laura M Ilharco; Alexandra Fidalgo; Rosa Alduina; Alessandro Presentato; Rosaria Ciriminna; Valentina Di Liberto
Journal:  Antioxidants (Basel)       Date:  2021-04-25

8.  Preventive Impact of Long-Term Ingestion of Chestnut Honey on Glucose Disorders and Neurodegeneration in Obese Mice.

Authors:  Simona Terzo; Pasquale Calvi; Domenico Nuzzo; Pasquale Picone; Giacoma Galizzi; Luca Caruana; Marta Di Carlo; Laura Lentini; Roberto Puleio; Flavia Mulè; Antonella Amato
Journal:  Nutrients       Date:  2022-02-11       Impact factor: 5.717

9.  Identification of Immune Cells and Key Genes associated with Alzheimer's Disease.

Authors:  Chenming Liu; Xi Zhang; Huazhen Chai; Sutong Xu; Qiulu Liu; Yuping Luo; Siguang Li
Journal:  Int J Med Sci       Date:  2022-01-01       Impact factor: 3.738
  9 in total

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