Literature DB >> 3232278

Intracavernous injection of vasoactive drugs in the rabbit.

W Stackl1, G Loupal, A Holzmann.   

Abstract

To investigate the erectile response and side effects of intracavernous injection of vasoactive agents, 7 groups of 5 rabbits each underwent injection of either isotonic saline or 1 of 6 drugs. Phentolamine most consistently produced full erection with few inflammatory reactions, while phenoxybenzamine produced erection but also severe inflammation and sclerosis of the corpus cavernosum. With prostaglandin E1, neither erection nor inflammation was observed.

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Year:  1988        PMID： 3232278     DOI： 10.1007/bf00280029

Source DB:  PubMed          Journal:  Urol Res        ISSN： 0300-5623


  12 in total

1.  The wall structure of the arteries in the corpora cavernosa penis of rabbits; light and electron microscopy.

Authors:  S Fujimoto; Y Takeshige
Journal:  Anat Rec       Date:  1975-03

2.  Auto-injection of the corpus cavernosum with a vasoactive drug combination for vasculogenic impotence.

Authors:  A W Zorgniotti; R S Lefleur
Journal:  J Urol       Date:  1985-01       Impact factor: 7.450

3.  Chronic papaverine treatment: the effect of repeated injections on the simian erectile response and penile tissue.

Authors:  M Abozeid; K P Juenemann; J A Luo; T F Lue; T S Yen; E A Tanagho
Journal:  J Urol       Date:  1987-11       Impact factor: 7.450

4.  Physiology of erection and pharmacological management of impotence.

Authors:  T F Lue; E A Tanagho
Journal:  J Urol       Date:  1987-05       Impact factor: 7.450

5.  Cavernosal alpha-blockade: a warning.

Authors:  A C Flind
Journal:  Br J Psychiatry       Date:  1984-03       Impact factor: 9.319

6.  Intracavernous injection of prostaglandin E1 in impotent men.

Authors:  W Stackl; R Hasun; M Marberger
Journal:  J Urol       Date:  1988-07       Impact factor: 7.450

7.  Intracavernous injection of papaverine as a diagnostic and therapeutic method in erectile failure.

Authors:  R Virag; D Frydman; M Legman; H Virag
Journal:  Angiology       Date:  1984-02       Impact factor: 3.619

8.  Contraction and relaxation induced by some prostanoids in isolated human penile erectile tissue and cavernous artery.

Authors:  H Hedlund; K E Andersson
Journal:  J Urol       Date:  1985-12       Impact factor: 7.450

9.  Diagnostic intracorporeal papaverine and erectile dysfunction.

Authors:  J R Strachan; J P Pryor
Journal:  Br J Urol       Date:  1987-03

10.  Pilot experiments on the actions of drugs injected into the human corpus cavernosum penis.

Authors:  G S Brindley
Journal:  Br J Pharmacol       Date:  1986-03       Impact factor: 8.739
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  2 in total

1.  The rabbit as an intracavernous injection study model.

Authors:  Y M Lin; J S Lin
Journal:  Urol Res       Date:  1996

Review 2.  Intracavernous prostaglandin E1 in erectile dysfunction.

Authors:  O I Linet; L L Neff
Journal:  Clin Investig       Date:  1994-01
  2 in total

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