Chen Sarbagili-Shabat1,2, Shira Zelber-Sagi3,4, Naomi Fliss Isakov3, Yulia Ron3, Ayal Hirsch3, Nitsan Maharshak3,5. 1. IBD Center, Department of Gastroenterology and Liver Diseases, Tel-Aviv Medical Center, Tel-Aviv, Israel. chen.sarbagili@gmail.com. 2. The Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. chen.sarbagili@gmail.com. 3. IBD Center, Department of Gastroenterology and Liver Diseases, Tel-Aviv Medical Center, Tel-Aviv, Israel. 4. School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Israel. 5. The Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Abstract
BACKGROUND: Processed foods have been implicated in the pathogenesis of inflammatory bowel diseases (IBD). Our goal was to develop a validated processed foods frequency questionnaire (PFQ) and assess its reliability and validity. METHODS: We recruited adult IBD patients to fill-in a PFQ in this prospective single-center study. Food intake was categorized into three groups of processed food levels: unprocessed, processed, and ultra-processed. Reliability was assessed by comparing the PFQ results of each patient at 2 time points. Validity was assessed by comparing the PFQ results to a 3-7 day food diary (FD), and by comparing urine sodium as a biomarker for the high intake of sodium that is mostly present in processed food. RESULTS: Eighty-six IBD patients were enrolled. Good test-retest reliability was indicated by intraclass correlation of 0.75-0.88 for the different food processing levels. Validity was fair-to-strong as assessed by correlations for different levels of processed food intake between FDs and PFQ, ranging between 0.43 and 0.64 (Pearsonr, P < 0.001), and further supported by higher mean urine sodium levels in patients with high processed foods consumption compared with low consumption (104.57 ± 53.26 vs. 78.62 ± 39.08 mmol/L, respectively, P = 0.022). Agreement between PFQ and the FD in categorizing patients to high and low processed food consumption groups was fair (Kappa 0.23-0.35). CONCLUSIONS: The PFQ is a reliable and valid tool for the assessment of processed foods consumption in IBD patients and can be utilized for studying the association between processed food consumption and IBD etiopathogenesis.
BACKGROUND: Processed foods have been implicated in the pathogenesis of inflammatory bowel diseases (IBD). Our goal was to develop a validated processed foods frequency questionnaire (PFQ) and assess its reliability and validity. METHODS: We recruited adult IBD patients to fill-in a PFQ in this prospective single-center study. Food intake was categorized into three groups of processed food levels: unprocessed, processed, and ultra-processed. Reliability was assessed by comparing the PFQ results of each patient at 2 time points. Validity was assessed by comparing the PFQ results to a 3-7 day food diary (FD), and by comparing urine sodium as a biomarker for the high intake of sodium that is mostly present in processed food. RESULTS: Eighty-six IBD patients were enrolled. Good test-retest reliability was indicated by intraclass correlation of 0.75-0.88 for the different food processing levels. Validity was fair-to-strong as assessed by correlations for different levels of processed food intake between FDs and PFQ, ranging between 0.43 and 0.64 (Pearsonr, P < 0.001), and further supported by higher mean urine sodium levels in patients with high processed foods consumption compared with low consumption (104.57 ± 53.26 vs. 78.62 ± 39.08 mmol/L, respectively, P = 0.022). Agreement between PFQ and the FD in categorizing patients to high and low processed food consumption groups was fair (Kappa 0.23-0.35). CONCLUSIONS: The PFQ is a reliable and valid tool for the assessment of processed foods consumption in IBD patients and can be utilized for studying the association between processed food consumption and IBD etiopathogenesis.
Authors: Natalie A Molodecky; Ing Shian Soon; Doreen M Rabi; William A Ghali; Mollie Ferris; Greg Chernoff; Eric I Benchimol; Remo Panaccione; Subrata Ghosh; Herman W Barkema; Gilaad G Kaplan Journal: Gastroenterology Date: 2011-10-14 Impact factor: 22.682
Authors: Celia Martinez-Perez; Lidia Daimiel; Cristina Climent-Mainar; Miguel Ángel Martínez-González; Jordi Salas-Salvadó; Dolores Corella; Helmut Schröder; Jose Alfredo Martinez; Ángel M Alonso-Gómez; Julia Wärnberg; Jesús Vioque; Dora Romaguera; José López-Miranda; Ramón Estruch; Francisco J Tinahones; José Lapetra; Lluis Serra-Majem; Aurora Bueno-Cavanillas; Josep A Tur; Vicente Martín Sánchez; Xavier Pintó; Miguel Delgado-Rodríguez; Pilar Matía-Martín; Josep Vidal; Clotilde Vázquez; Emilio Ros; Javier Basterra; Nancy Babio; Patricia Guillem-Saiz; María Dolores Zomeño; Itziar Abete; Jessica Vaquero-Luna; Francisco Javier Barón-López; Sandra Gonzalez-Palacios; Jadwiga Konieczna; Antonio Garcia-Rios; María Rosa Bernal-López; José Manuel Santos-Lozano; Maira Bes-Rastrollo; Nadine Khoury; Carmen Saiz; Karla Alejandra Pérez-Vega; María Angeles Zulet; Lucas Tojal-Sierra; Zenaida Vázquez Ruiz; Maria Angeles Martinez; Mireia Malcampo; José M Ordovás; Rodrigo San-Cristobal Journal: Int J Behav Nutr Phys Act Date: 2022-01-24 Impact factor: 6.457