Literature DB >> 32318167

Written in the Body?: Healing the Epigenetic Molecular Wounds of Complex Trauma Through Empathy and Kindness.

Ivana Lucero1.   

Abstract

While research on the biological/genetic approach to trauma transmission has become increasingly abundant over the past 15 years, this research has been primarily limited to scientific research journals and has not yet significantly appeared in practice journals, graduate programs, clinical settings, or policy decisions. This paper aims to develop a bridge across disciplines, integrating a review of biological science literature with mental health literature to provide a multidisciplinary overview of the role of epigenetic mechanisms in the transmission of complex trauma. Such a multidisciplinary overview is important in allowing professionals across disciplines to approach their work with a more complete understanding of the way in which ecological systems shape trauma transmission and healing. While encouraging collaboration between researchers and providers across fields, this paper argues that to heal the person, one must first work to heal the environment. © Springer International Publishing AG, part of Springer Nature 2018.

Entities:  

Keywords:  Intergenerational; Neurobiological stress susceptibility; Neurodevelopmentally-informed care; Person-in-environment; Resilience; Somatic stress; Transgenerational

Year:  2018        PMID: 32318167      PMCID: PMC7163842          DOI: 10.1007/s40653-018-0205-0

Source DB:  PubMed          Journal:  J Child Adolesc Trauma        ISSN: 1936-1521


  29 in total

Review 1.  Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations.

Authors:  M J Meaney
Journal:  Annu Rev Neurosci       Date:  2001       Impact factor: 12.449

Review 2.  Epigenetic transmission of Holocaust trauma: can nightmares be inherited?

Authors:  Natan Pf Kellermann
Journal:  Isr J Psychiatry Relat Sci       Date:  2013       Impact factor: 0.481

3.  Thoughts and Response to Authority-Perpetrated, Discriminatory, and Race-Based Violence.

Authors:  Kimlin Tam Ashing; Marva L Lewis; Valencia P Walker
Journal:  JAMA Pediatr       Date:  2017-06-01       Impact factor: 16.193

4.  Genome-wide epigenetic regulation by early-life trauma.

Authors:  Benoit Labonté; Matt Suderman; Gilles Maussion; Luis Navaro; Volodymyr Yerko; Ian Mahar; Alexandre Bureau; Naguib Mechawar; Moshe Szyf; Michael J Meaney; Gustavo Turecki
Journal:  Arch Gen Psychiatry       Date:  2012-07

5.  Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse.

Authors:  Patrick O McGowan; Aya Sasaki; Ana C D'Alessio; Sergiy Dymov; Benoit Labonté; Moshe Szyf; Gustavo Turecki; Michael J Meaney
Journal:  Nat Neurosci       Date:  2009-03       Impact factor: 24.884

6.  Lasting epigenetic influence of early-life adversity on the BDNF gene.

Authors:  Tania L Roth; Farah D Lubin; Adam J Funk; J David Sweatt
Journal:  Biol Psychiatry       Date:  2009-01-15       Impact factor: 13.382

Review 7.  Neural and behavioral epigenetics; what it is, and what is hype.

Authors:  A R Isles
Journal:  Genes Brain Behav       Date:  2015-01       Impact factor: 3.449

8.  Childhood adversity and epigenetic modulation of the leukocyte glucocorticoid receptor: preliminary findings in healthy adults.

Authors:  Audrey R Tyrka; Lawrence H Price; Carmen Marsit; Oakland C Walters; Linda L Carpenter
Journal:  PLoS One       Date:  2012-01-25       Impact factor: 3.240

9.  Transgenerational Epigenetic Contributions to Stress Responses: Fact or Fiction?

Authors:  Eric J Nestler
Journal:  PLoS Biol       Date:  2016-03-25       Impact factor: 8.029

10.  Transgenerational transmission of trauma and resilience: a qualitative study with Brazilian offspring of Holocaust survivors.

Authors:  Luciana Lorens Braga; Marcelo Feijó Mello; José Paulo Fiks
Journal:  BMC Psychiatry       Date:  2012-09-03       Impact factor: 3.630

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