Literature DB >> 24029109

Epigenetic transmission of Holocaust trauma: can nightmares be inherited?

Natan Pf Kellermann1.   

Abstract

The Holocaust left its visible and invisible marks not only on the survivors, but also on their children. Instead of numbers tattooed on their forearms, however, they may have been marked epigenetically with a chemical coating upon their chromosomes, which would represent a kind of biological memory of what the parents experienced. as a result, some suffer from a general vulnerability to stress while others are more resilient. Previous research assumed that such transmission was caused by environmental factors, such as the parents' childrearing behavior. New research, however, indicates that these transgenerational effects may have been also (epi) genetically transmitted to their children. Integrating both hereditary and environmental factors, epigenetics adds a new and more comprehensive psychobiological dimension to the explanation of transgenerational transmission of trauma. Specifically, epigenetics may explain why latent transmission becomes manifest under stress. a general theoretical overview of epigenetics and its relevance to research on trauma transmission is presented.

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Year:  2013        PMID: 24029109

Source DB:  PubMed          Journal:  Isr J Psychiatry Relat Sci        ISSN: 0333-7308            Impact factor:   0.481


  10 in total

1.  Hidden Burdens: a Review of Intergenerational, Historical and Complex Trauma, Implications for Indigenous Families.

Authors:  Linda O'Neill; Tina Fraser; Andrew Kitchenham; Verna McDonald
Journal:  J Child Adolesc Trauma       Date:  2016-10-28

2.  Written in the Body?: Healing the Epigenetic Molecular Wounds of Complex Trauma Through Empathy and Kindness.

Authors:  Ivana Lucero
Journal:  J Child Adolesc Trauma       Date:  2018-02-24

Review 3.  Epigenetic mechanisms underlying learning and the inheritance of learned behaviors.

Authors:  Brian G Dias; Stephanie Maddox; Torsten Klengel; Kerry J Ressler
Journal:  Trends Neurosci       Date:  2014-12-24       Impact factor: 13.837

4.  Parental Post-traumatic Stress Disorder Symptoms Are Related to Successful Aging in Offspring of Holocaust Survivors.

Authors:  Amit Shrira; Liat Ayalon; Moshe Bensimon; Ehud Bodner; Tova Rosenbloom; Gal Yadid
Journal:  Front Psychol       Date:  2017-06-29

5.  Epigenetic Inheritance: Concepts, Mechanisms and Perspectives.

Authors:  Irene Lacal; Rossella Ventura
Journal:  Front Mol Neurosci       Date:  2018-09-28       Impact factor: 5.639

6.  Secondary Traumatization, Psychological Stress, and Resilience in Psychosocial Emergency Care Personnel.

Authors:  Anja Greinacher; Alexander Nikendei; Renate Kottke; Jürgen Wiesbeck; Wolfgang Herzog; Christoph Nikendei
Journal:  Int J Environ Res Public Health       Date:  2019-09-03       Impact factor: 3.390

Review 7.  The social construction of the social epigenome and the larger biological context.

Authors:  Ute Deichmann
Journal:  Epigenetics Chromatin       Date:  2020-09-23       Impact factor: 4.954

Review 8.  Update on the neurodevelopmental theory of depression: is there any 'unconscious code'?

Authors:  Małgorzata Gałecka; Katarzyna Bliźniewska-Kowalska; Michael Maes; Kuan-Pin Su; Piotr Gałecki
Journal:  Pharmacol Rep       Date:  2020-12-31       Impact factor: 3.024

9.  Transgenerational Transmission of Trauma across Three Generations of Alevi Kurds.

Authors:  Jan Ilhan Kizilhan; Michael Noll-Hussong; Thomas Wenzel
Journal:  Int J Environ Res Public Health       Date:  2021-12-22       Impact factor: 3.390

10.  Transgenerational inheritance of fetal alcohol effects on proopiomelanocortin gene expression and methylation, cortisol response to stress, and anxiety-like behaviors in offspring for three generations in rats: Evidence for male germline transmission.

Authors:  Omkaram Gangisetty; Shaista Chaudhary; Ajay Palagani; Dipak K Sarkar
Journal:  PLoS One       Date:  2022-02-10       Impact factor: 3.240

  10 in total

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