Hypersphere clustering to characterize healthcare providers using prescriptions and procedures from Medicare claims data.

We consider the task of producing a useful clustering of healthcare providers from their clinical action signature- their drug, procedure, and billing codes. Because high-dimensional sparse count vectors are challenging to cluster, we develop a novel autoencoder framework to address this task. Our solution creates a low-dimensional embedded representation of the high-dimensional space that preserves angular relationships and assigns examples to clusters while optimizing the quality of this clustering. Our method is able to find a better clustering than under a two-step alternative, e.g., projected K means/medoids, where a representation is learned and then clustering is applied to the representation. We demonstrate our method's characteristics through quantitative and qualitative analysis of real and simulated data, including in several real-world healthcare case studies. Finally, we develop a tool to enhance exploratory analysis of providers based on their clinical behaviors. ©2019 AMIA - All rights reserved.