Literature DB >> 32299161

Gene expression of fatty acid binding protein genes and its relationship with fat deposition of Thai native crossbreed chickens.

Supanon Tunim1, Yupin Phasuk1,2, Samuel E Aggrey3, Monchai Duangjinda1,2.   

Abstract

OBJECTIVE: The objectives of this study were to investigate the relationship between the mRNA expression of adipocyte type fatty acid binding protein (A-FABP) and heart type FABP (H-FABP) in Thai native chicken crossbreeds and evaluate the level of exotic inclusion in native chicken that will improve growth while maintaining its relatively low carcass fat.
METHODS: The fat deposition traits and mRNA expression of A-FABP and H-FABP were evaluated at 6, 8, 10, and 12 weeks of age in 4 chicken breeds (n = 8/breed/wk) (100% Chee breed [CH] [100% Thai native chicken background], CH male and broiler female [Kaimook e-san1; KM1] [50% CH background], broiler male and KM1 female [Kaimook e-san2; KM2] [25% CH background], and broiler [BR]) using abdominal fat (ABF) and muscular tissues.
RESULTS: The BR breed was only evaluated at 6 weeks of age. At week 6, the CH breed had a significantly lower A-FABP expression in ABF and intramuscular fat (IF) compared with the other breeds. At 8 to 12 weeks, the KM2 groups showed significant upregulation (p<0.05) of A-FABP in both ABF and IF compared to the CH and KM1 groups. The expression of H-FABP did not follow any consistent pattern in both ABF and IF across the different ages.
CONCLUSION: Some level of crossbreeding CH chickens can be done to improve growth rate while maintaining their low ABF and IF. The expression level of A-FABP correlate with most fat traits. There was no consistency of H-FABP expression across breed. A-FABPs is involved in fat deposition, genetic markers in these genes could be used in marker assisted studies to select against excessive fat accumulation.

Entities:  

Keywords:  Correlation; Crossbreed Chicken; Fat Deposition; Fatty Acid Binding Proteins (FABPs); Gene Expression

Year:  2020        PMID: 32299161      PMCID: PMC7961282          DOI: 10.5713/ajas.20.0020

Source DB:  PubMed          Journal:  Anim Biosci        ISSN: 2765-0189


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