| Literature DB >> 32288187 |
T D Nguyen1, E Bottreau1, J M Aynaud1.
Abstract
At a concentration of 2 μg/ml, neither amphotericin B nor deoxycholate had an inactivating effect upon transmissible gastroenteritis Coronavirus in-fectivity. However, amphothericin B stimulated plaque formatin in agarose and facilitated the entry of viral RNA into swine testis cells. The combination of amphotericin B + deoxycholate inactivated virus infectivity and induced a decrease in plaque diameter. Finally, in the presence of these agents, the production of infectious virus and interferon was unchanged.Entities:
Keywords: Swine, In vitro; TGE virus, Coronavirus, Fongizone, Amphotericin B, Deoxycholate, Gastroenteritis
Year: 2009 PMID: 32288187 PMCID: PMC7135538 DOI: 10.1016/S0769-2617(87)80019-9
Source DB: PubMed Journal: Ann Inst Pasteur Virol ISSN: 0769-2617