Literature DB >> 32279946

Utilization of Debridement, Antibiotics, and Implant Retention for Infection After Total Joint Arthroplasty Over a Decade in the United States.

K Keely Boyle1, Milan Kapadia2, David C Landy1, Michael W Henry2, Andy O Miller2, Geoffrey H Westrich1.   

Abstract

BACKGROUND: Reported clinical outcomes have varied for debridement, antibiotics, and implant retention (DAIR) and little is known regarding trends in utilization. We sought to evaluate the rate of DAIR utilization for total knee arthroplasty (TKA) and total hip arthroplasty (THA) periprosthetic joint infection (PJI) over a decade and clinical factors associated with these trends.
METHODS: A retrospective study of primary TKAs and THAs was performed using Medicare data from 2005 to 2014 using the PearlDiver database platform. Current Procedural Technology and International Classification of Diseases Ninth Edition codes identified patients who underwent a surgical revision for PJI, whether revision was a DAIR, as well as associated clinical factors including timing from index arthroplasty.
RESULTS: The proportion of revision TKAs and THAs performed using DAIR was 27% and 12% across all years, respectively. This proportion varied by year for TKAs and THAs with a linear trend toward increasing relative use of DAIR estimated at 1.4% and 0.9% per year (P < .001; P < .001). DAIR for TKA and THA performed within 90 days increased at a faster rate, 3.4% and 2.1% per year (P < .001; P < .001). Trends over time in TKA DAIRs showed an association with Elixhauser Comorbidity Index (ECI), 0-5 group increasing at 2.0% per year (P = .03) and patients >85 years (P = .04).
CONCLUSION: The proportion of revision arthroplasty cases for PJI managed with DAIR has been increasing over time in the United States, with the most substantial increase seen <90 days from index arthroplasty. Age, gender, and ECI had a minimal association with this trend, except in the TKA population >85 years and in those with a very low ECI score.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  DAIR; PearlDiver; irrigation and debridement; periprosthetic joint infection; total hip arthroplasty; total knee arthroplasty

Mesh:

Substances:

Year:  2020        PMID: 32279946     DOI: 10.1016/j.arth.2020.03.029

Source DB:  PubMed          Journal:  J Arthroplasty        ISSN: 0883-5403            Impact factor:   4.757


  4 in total

Review 1.  Treatment patterns and failure rates associated with prosthetic joint infection in unicompartmental knee arthroplasty: A systematic review.

Authors:  Joseph P Barbera; Ryan C Xiao; Christine S Williams; Jashvant Poeran; Calin S Moucha; Darwin D Chen; Brett L Hayden
Journal:  J Orthop       Date:  2022-09-14

2.  Comparison of the success rate after debridement, antibiotics and implant retention (DAIR) for periprosthetic joint infection among patients with or without a sinus tract.

Authors:  Wang Deng; Rui Li; Hongyi Shao; Baozhan Yu; Jiying Chen; Yixin Zhou
Journal:  BMC Musculoskelet Disord       Date:  2021-10-21       Impact factor: 2.362

3.  Bacteremia in Patients Undergoing Debridement, Antibiotics, and Implant Retention Leads to Increased Reinfections and Costs.

Authors:  Samuel Rosas; Vishal Hegde; F Johannes Plate; Douglas Dennis; Jason Jennings; Daniel N Bracey
Journal:  Arthroplast Today       Date:  2022-07-19

4.  Effectiveness and Optimal Duration of Adjunctive Rifampin Treatment in the Management of Staphylococcus aureus Prosthetic Joint Infections After Debridement, Antibiotics, and Implant Retention.

Authors:  Hiroyuki Suzuki; Michihiko Goto; Rajeshwari Nair; Daniel J Livorsi; Poorani Sekar; Michael E Ohl; Daniel J Diekema; Eli N Perencevich; Bruce Alexander; Michael P Jones; Jennifer S McDaniel; Marin L Schweizer
Journal:  Open Forum Infect Dis       Date:  2022-09-12       Impact factor: 4.423

  4 in total

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