Literature DB >> 32279845

Human lumbar spinal column injury criteria from vertical loading at the base: Applications to military environments.

Narayan Yoganandan1, Jason Moore2, Nicholas DeVogel3, Frank Pintar4, Anjishnu Banerjee3, Jamie Baisden2, Jiang Yue Zhang5, Kathryn Loftis6, David Barnes7.   

Abstract

The objective of this study was to determine force-based lumbar spine injury criteria due to vertical impact using Post Mortem Human Surrogate (PMHS) experiments. Mounted personnel in military vehicles sustain loads from the pelvis in combat events such as underbody blast loadings. Forty-three post mortem human subject thoracolumbar spinal columns were obtained, screened for pre-existing trauma, bone mineral densities (BMDs) were determined, pre-test radiological images were taken, fixed at the ends in polymethylmethacrylate, load cells were attached to the ends of the fixation, positioned on custom vertical accelerator device based on a military-seating posture, and impacted at the base. Posttest images were obtained, and gross dissection was done to confirm injuries, classified into single and multilevel groups, groups A and B. Axial and resultant forces at the thoracolumbar (proximal) and lumbosacral (distal) joints were used as response variables to develop lumbar spine injury risk curves using parametric survival analysis. The Brier score metric was used to rank the variables. Age, BMD, column length, and vertebral body and intervertebral disc areas were used as covariates. The optimal metric describing the underlying response to injury was the distal resultant force for group A and proximal axial force for group B specimens. Force-BMD for group A and force-body area for group B were the best combinations. The IRCs with ±95% confidence intervals and quality of risk curves are given in the paper, and they serve as lumbar spine injury criteria. The present human cadaver Injury Risk Curves (IRCs) can be used to conduct matched pair tests to obtain dummy-based injury assessment risk curves/values to predict injury. The present IRCs can be used in human body finite element models. The relationship between covariates and primary forces presented in this study contribute to a better understanding of the role of demographic, geometric, and material factors to impact acceleration loading. Published by Elsevier Ltd.

Entities:  

Keywords:  Biomechanics; Impact injuries; Injury risk curves; Statistical modeling

Mesh:

Year:  2020        PMID: 32279845      PMCID: PMC9555006          DOI: 10.1016/j.jmbbm.2020.103690

Source DB:  PubMed          Journal:  J Mech Behav Biomed Mater        ISSN: 1878-0180


  32 in total

1.  Bone mineral density of human female cervical and lumbar spines from quantitative computed tomography.

Authors:  Narayan Yoganandan; Frank A Pintar; Brian D Stemper; Jamie L Baisden; Recai Aktay; Barry S Shender; Glenn Paskoff
Journal:  Spine (Phila Pa 1976)       Date:  2006-01-01       Impact factor: 3.468

2.  Survival Analysis-Based Human Head Injury Risk Curves: Focus on Skull Fracture.

Authors:  Narayan Yoganandan; Anjishnu Banerjee
Journal:  J Neurotrauma       Date:  2018-03-29       Impact factor: 5.269

3.  Forces and moments in cervical spinal column segments in frontal impacts using finite element modeling and human cadaver tests.

Authors:  Frank Meyer; John Humm; Yuvaraj Purushothaman; Rémy Willinger; Frank A Pintar; Narayan Yoganandan
Journal:  J Mech Behav Biomed Mater       Date:  2018-10-02

4.  Deriving injury risk curves using survival analysis from biomechanical experiments.

Authors:  Narayan Yoganandan; Anjishnu Banerjee; Fang-Chi Hsu; Cameron R Bass; Liming Voo; Frank A Pintar; F Scott Gayzik
Journal:  J Biomech       Date:  2016-08-09       Impact factor: 2.712

5.  Retrospective Analysis of Injuries in Underbody Blast Events: 2007-2010.

Authors:  Kimberly B Vasquez; Frederick T Brozoski; Katie P Logsdon; Valeta C Chancey
Journal:  Mil Med       Date:  2018-03-01       Impact factor: 1.437

6.  Characterization of combat-related spinal injuries sustained by a US Army Brigade Combat Team during Operation Iraqi Freedom.

Authors:  Andrew J Schoenfeld; Gens P Goodman; Philip J Belmont
Journal:  Spine J       Date:  2010-06-11       Impact factor: 4.166

7.  Burst fractures of the lumbar spine in frontal crashes.

Authors:  Robert P Kaufman; Randal P Ching; Margaret M Willis; Christopher D Mack; Joel A Gross; Eileen M Bulger
Journal:  Accid Anal Prev       Date:  2013-06-03

8.  Microtrauma in the lumbar spine: a cause of low back pain.

Authors:  N Yoganandan; D J Maiman; F Pintar; G Ray; J B Myklebust; A Sances; S J Larson
Journal:  Neurosurgery       Date:  1988-08       Impact factor: 4.654

9.  Comparison of ATD to PMHS Response in the Under-Body Blast Environment.

Authors:  Kerry A Danelson; Andrew R Kemper; Matthew J Mason; Michael Tegtmeyer; Sean A Swiatkowski; John H Bolte; Warren N Hardy
Journal:  Stapp Car Crash J       Date:  2015-11

10.  Human Foot-Ankle Injuries and Associated Risk Curves from Under Body Blast Loading Conditions.

Authors:  Sajal Chirvi; Frank Pintar; Narayan Yoganandan; Anjishnu Banerjee; Mike Schlick; William Curry; Liming Voo
Journal:  Stapp Car Crash J       Date:  2017-11
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.