Literature DB >> 32259785

NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 1.2020.

Mary B Daly1, Robert Pilarski2, Matthew B Yurgelun3, Michael P Berry4, Saundra S Buys5, Patricia Dickson6, Susan M Domchek7, Ahmed Elkhanany8, Susan Friedman9, Judy E Garber3, Michael Goggins10, Mollie L Hutton11, Seema Khan12, Catherine Klein13, Wendy Kohlmann5, Allison W Kurian14, Christine Laronga15, Jennifer K Litton16, Julie S Mak17, Carolyn S Menendez18, Sofia D Merajver19, Barbara S Norquist20, Kenneth Offit21, Tuya Pal22, Holly J Pederson23, Gwen Reiser24, Kristen Mahoney Shannon25, Kala Visvanathan10, Jeffrey N Weitzel26, Myra J Wick27, Kari B Wisinski28, Mary A Dwyer29, Susan D Darlow29.   

Abstract

The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic provide recommendations for genetic testing and counseling for hereditary cancer syndromes, and risk management recommendations for patients who are diagnosed with syndromes associated with an increased risk of these cancers. The NCCN panel meets at least annually to review comments, examine relevant new data, and reevaluate and update recommendations. These NCCN Guidelines Insights summarize the panel's discussion and most recent recommendations regarding criteria for high-penetrance genes associated with breast and ovarian cancer beyond BRCA1/2, pancreas screening and genes associated with pancreatic cancer, genetic testing for the purpose of systemic therapy decision-making, and testing for people with Ashkenazi Jewish ancestry.

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Year:  2020        PMID: 32259785     DOI: 10.6004/jnccn.2020.0017

Source DB:  PubMed          Journal:  J Natl Compr Canc Netw        ISSN: 1540-1405            Impact factor:   11.908


  104 in total

1.  Management of Breast Cancer During the COVID-19 Pandemic: A Stage- and Subtype-Specific Approach.

Authors:  Jennifer Y Sheng; Cesar A Santa-Maria; Neha Mangini; Haval Norman; Rima Couzi; Raquel Nunes; Mary Wilkinson; Kala Visvanathan; Roisin M Connolly; Evanthia T Roussos Torres; John H Fetting; Deborah K Armstrong; Jessica J Tao; Lisa Jacobs; Jean L Wright; Elissa D Thorner; Christine Hodgdon; Samantha Horn; Antonio C Wolff; Vered Stearns; Karen L Smith
Journal:  JCO Oncol Pract       Date:  2020-06-30

Review 2.  Management of Secondary Genomic Findings.

Authors:  Alexander E Katz; Robert L Nussbaum; Benjamin D Solomon; Heidi L Rehm; Marc S Williams; Leslie G Biesecker
Journal:  Am J Hum Genet       Date:  2020-07-02       Impact factor: 11.025

3.  Presymptomatic Awareness of Germline Pathogenic BRCA Variants and Associated Outcomes in Women With Breast Cancer.

Authors:  Tal Hadar; Pnina Mor; Gefen Amit; Sari Lieberman; David Gekhtman; Rachel Rabinovitch; Ephrat Levy-Lahad
Journal:  JAMA Oncol       Date:  2020-09-01       Impact factor: 31.777

Review 4.  Practical Considerations and Challenges for Germline Genetic Testing in Patients With Prostate Cancer: Recommendations From the Germline Genetics Working Group of the PCCTC.

Authors:  Brittany M Szymaniak; Lauren A Facchini; Veda N Giri; Emmanuel S Antonarakis; Tomasz M Beer; Maria I Carlo; Daniel C Danila; Mallika Dhawan; Daniel George; Julie N Graff; Shilpa Gupta; Elisabeth Heath; Celestia S Higano; Glenn Liu; Ana M Molina; Channing J Paller; Akash Patnaik; Daniel P Petrylak; Zachery Reichert; Matthew B Rettig; Charles J Ryan; Mary-Ellen Taplin; Jake Vinson; Young E Whang; Alicia K Morgans; Heather H Cheng; Rana R McKay
Journal:  JCO Oncol Pract       Date:  2020-09-28

5.  Germline and tumor BRCA1/2 pathogenic variants in Chinese triple-negative breast carcinomas.

Authors:  Gang Ji; Longlong Bao; Qianlan Yao; Jing Zhang; Xiaoli Zhu; Qianming Bai; Zhiming Shao; Wentao Yang; Xiaoyan Zhou
Journal:  J Cancer Res Clin Oncol       Date:  2021-07-13       Impact factor: 4.553

6.  EUS-based Pancreatic Cancer Surveillance in BRCA1/BRCA2/PALB2/ATM Carriers Without a Family History of Pancreatic Cancer.

Authors:  Bryson W Katona; Jessica M Long; Nuzhat A Ahmad; Sara Attalla; Angela R Bradbury; Erica L Carpenter; Dana F Clark; Gillain Constantino; Koushik K Das; Susan M Domchek; Christina Dudzik; Jessica Ebrahimzadeh; Gregory G Ginsberg; Jordan Heiman; Michael L Kochman; Kara N Maxwell; Danielle B McKenna; Jacquelyn Powers; Payal D Shah; Kirk J Wangensteen; Anil K Rustgi
Journal:  Cancer Prev Res (Phila)       Date:  2021-08-02

7.  Influence of payer coverage and out-of-pocket costs on ordering of NGS panel tests for hereditary cancer in diverse settings.

Authors:  Grace A Lin; Julia R Trosman; Michael P Douglas; Christine B Weldon; Maren T Scheuner; Allison Kurian; Kathryn A Phillips
Journal:  J Genet Couns       Date:  2021-07-07       Impact factor: 2.537

8.  Clinical and psychological outcomes of receiving a variant of uncertain significance from multigene panel testing or genomic sequencing: a systematic review and meta-analysis.

Authors:  Chloe Mighton; Salma Shickh; Elizabeth Uleryk; Petros Pechlivanoglou; Yvonne Bombard
Journal:  Genet Med       Date:  2020-09-14       Impact factor: 8.822

9.  Implications of Multigene Panel Testing on Psychosocial Outcomes: A Comparison of Patients With Pancreatic and Breast or Ovarian Cancer.

Authors:  Cathryn Koptiuch; Whitney F Espinel; Wendy K Kohlmann; Jingsong Zhao; Kimberly A Kaphingst
Journal:  JCO Precis Oncol       Date:  2021-01-19

10.  The evolving role of germline genetic testing and management in prostate cancer: Report from the Princess Margaret Cancer Centre international retreat.

Authors:  Roderick Clark; Miran Kenk; Kristen McAlpine; Emily Thain; Kirsten M Farncombe; Colin C Pritchard; Robert Nussbaum; Alexander W Wyatt; Johann de Bono; Danny Vesprini; Yvonne Bombard; Justin Lorentz; Steven Narod; Raymond Kim; Neil Fleshner
Journal:  Can Urol Assoc J       Date:  2021-12       Impact factor: 1.862

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