| Literature DB >> 32258590 |
Eva M Serrao1,2, Kevin M Brindle1,2.
Abstract
As clinical oncology evolves with new treatment options becoming available, there is an increasing demand on anatomic imaging for the assessment of patients at different stages. Imaging with hyperpolarized 13C-labelled cell substrates has the potential to become a powerful tool in many steps of clinical evaluation, offering a new metabolic metric and therefore a more personalised approach to treatment response. This articles explores the metabolic basis and potential for translation of hyperpolarised pyruvate as a dynamic nuclear polarisation probe in clinical oncology. Copyright 2017 PBJ-Associação Porto Biomedical/Porto Biomedical Society.Entities:
Keywords: Cancer; Hyperpolarized; Imaging; Metabolism; Pyruvate
Year: 2017 PMID： 32258590 PMCID： PMC6806983 DOI： 10.1016/j.pbj.2017.01.002
Source DB: PubMed Journal: Porto Biomed J ISSN： 2444-8664