Literature DB >> 32253498

[The immune system of adipose tissue: obesity-associated inflammation].

Pamela Fischer-Posovszky1, Peter Möller2.   

Abstract

Adipose tissue is an important endocrine organ. Via its secretion products, it cross-talks with other organs of the body and communicates the filling state of its triglyceride stores. Obesity is characterized by the excessive accumulation of body fat and leads to the infiltration and accumulation of immune cells in white adipose tissue. In this review article we introduce the various immune cell populations of adipose tissue and discuss their local and systemic influence.

Entities:  

Keywords:  Adipokine; Brown adipose tissue; Macrophages; Overweight; White adipose tissue

Year:  2020        PMID: 32253498     DOI: 10.1007/s00292-020-00782-z

Source DB:  PubMed          Journal:  Pathologe        ISSN: 0172-8113            Impact factor:   1.011


  56 in total

1.  Obesity induces a phenotypic switch in adipose tissue macrophage polarization.

Authors:  Carey N Lumeng; Jennifer L Bodzin; Alan R Saltiel
Journal:  J Clin Invest       Date:  2007-01       Impact factor: 14.808

2.  B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies.

Authors:  Daniel A Winer; Shawn Winer; Lei Shen; Persis P Wadia; Jason Yantha; Geoffrey Paltser; Hubert Tsui; Ping Wu; Matthew G Davidson; Michael N Alonso; Hwei X Leong; Alec Glassford; Maria Caimol; Justin A Kenkel; Thomas F Tedder; Tracey McLaughlin; David B Miklos; H-Michael Dosch; Edgar G Engleman
Journal:  Nat Med       Date:  2011-04-17       Impact factor: 53.440

Review 3.  Cancer as a Matter of Fat: The Crosstalk between Adipose Tissue and Tumors.

Authors:  Ernst Lengyel; Liza Makowski; John DiGiovanni; Mikhail G Kolonin
Journal:  Trends Cancer       Date:  2018-04-05

Review 4.  B Lymphocytes in obesity-related adipose tissue inflammation and insulin resistance.

Authors:  Daniel A Winer; Shawn Winer; Melissa H Y Chng; Lei Shen; Edgar G Engleman
Journal:  Cell Mol Life Sci       Date:  2013-10-15       Impact factor: 9.261

5.  Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine.

Authors:  Roksana M Pirzgalska; Elsa Seixas; Jason S Seidman; Verena M Link; Noelia Martínez Sánchez; Inês Mahú; Raquel Mendes; Vitka Gres; Nadiya Kubasova; Imogen Morris; Bernardo A Arús; Chelsea M Larabee; Miguel Vasques; Francisco Tortosa; Ana L Sousa; Sathyavathy Anandan; Erin Tranfield; Maureen K Hahn; Matteo Iannacone; Nathanael J Spann; Christopher K Glass; Ana I Domingos
Journal:  Nat Med       Date:  2017-10-09       Impact factor: 53.440

6.  Annual Report to the Nation on the status of cancer, 1975-2008, featuring cancers associated with excess weight and lack of sufficient physical activity.

Authors:  Christie Eheman; S Jane Henley; Rachel Ballard-Barbash; Eric J Jacobs; Maria J Schymura; Anne-Michelle Noone; Liping Pan; Robert N Anderson; Janet E Fulton; Betsy A Kohler; Ahmedin Jemal; Elizabeth Ward; Marcus Plescia; Lynn A G Ries; Brenda K Edwards
Journal:  Cancer       Date:  2012-03-28       Impact factor: 6.860

7.  The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells.

Authors:  Ajithkumar Vasanthakumar; Kazuyo Moro; Annie Xin; Yang Liao; Renee Gloury; Shimpei Kawamoto; Sidonia Fagarasan; Lisa A Mielke; Shoukat Afshar-Sterle; Seth L Masters; Susumu Nakae; Hirohisa Saito; John M Wentworth; Peng Li; Wei Liao; Warren J Leonard; Gordon K Smyth; Wei Shi; Stephen L Nutt; Shigeo Koyasu; Axel Kallies
Journal:  Nat Immunol       Date:  2015-01-19       Impact factor: 25.606

8.  Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding.

Authors:  Vered Elgazar-Carmon; Assaf Rudich; Nurit Hadad; Rachel Levy
Journal:  J Lipid Res       Date:  2008-05-23       Impact factor: 5.922

9.  Assessment of oxidative metabolism in brown fat using PET imaging.

Authors:  Otto Muzik; Thomas J Mangner; James G Granneman
Journal:  Front Endocrinol (Lausanne)       Date:  2012-02-08       Impact factor: 5.555

Review 10.  Emerging Functions of Regulatory T Cells in Tissue Homeostasis.

Authors:  Amit Sharma; Dipayan Rudra
Journal:  Front Immunol       Date:  2018-04-25       Impact factor: 7.561

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