Literature DB >> 32246914

Essential care of critical illness must not be forgotten in the COVID-19 pandemic.

Tim Baker1, Carl Otto Schell2, Dan Brun Petersen3, Hendry Sawe4, Karima Khalid5, Samson Mndolo6, Jamie Rylance7, Daniel F McAuley8, Nobhojit Roy9, John Marshall10, Lee Wallis11, Elizabeth Molyneux12.   

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Year:  2020        PMID: 32246914      PMCID: PMC7270584          DOI: 10.1016/S0140-6736(20)30793-5

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


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The coronavirus disease 2019 (COVID-19) pandemic will have a large impact in low-resource settings (LRS). 20% of COVID-19 patients become critically ill with hypoxia or respiratory failure (figure ). Critical illness, describing any acute life-threatening condition, is receiving increased attention in global health because of its large disease burden and population impact. Before the COVID-19 pandemic, growing evidence suggested that the care of critical illness was overlooked in LRS—hospitals cannot, or do not, prioritise emergency and critical care. Most critically ill patients are cared for in emergency units and general wards and do not have access to advanced care in intensive care units (ICUs). Data from hospital wards in Malawi showed that 89% of hypoxic patients (oxygen saturation <90%) were not receiving oxygen, and 53% of unconscious patients (Glasgow Coma Scale <9) were being nursed supine without a protected airway (unpublished data).
Figure

Severity profile of coronavirus disease 2019

Data source: Wu et al (2020).

Severity profile of coronavirus disease 2019 Data source: Wu et al (2020). The COVID-19 pandemic will lead to a surge in the number of critically ill patients. Hospitals throughout the world will become overwhelmed, and care will be provided at a lower resource level than usual. Along with preventive measures and infection control, the clinical care of these patients will be a fundamental determinant of the pandemic's overall impact. Unfortunately, the headline figures of ICU requirements for COVID-19 patients in resource-rich settings are masking the need for essential care. Attention is directed towards expensive, high-tech equipment that demands highly trained providers while neglecting low-cost essential care. To avoid this neglect, we recommend a primary policy focus on basic, effective actions with potential population impact. A conceptual framework has recently been proposed that illustrates the need for hospital readiness and good quality clinical practice for the dual aspects of identification and care of critically ill patients (appendix). Hospitals should establish effective systems for triage and essential care in emergency units and wards, including patient separation and staff safety. User-friendly, concise protocols should be developed, disseminated, and implemented for good quality and feasible clinical care, with WHO's leadership and through national authorities. Simple physiological signs have been shown to identify critical illness, and single-parameter systems might be easier to use than compound scores. The central role of oxygen therapy should be emphasised, oxygen supplies and delivery systems secured, and guidelines for sustainable and appropriate use issued. Other essential care includes a head-up patient position, suction, and simple chest physiotherapy. When human resources are limited, such care can be implemented by less trained health workers or vital-signs assistants through a protocolised approach and task sharing. Quality essential care of critical illness could have a large positive effect on mortality even without ICUs. It would ameliorate the fatalism and passivity that arises from an absence of high-resource treatment options. Moreover, provision of essential care could prevent progression to multi-organ failure, reducing the burden on limited ICU capacity. The ability of health services in LRS and throughout the world to provide good quality essential care of critical illness must be greatly and urgently increased.
  4 in total

1.  Managing COVID-19 in Low- and Middle-Income Countries.

Authors:  Joost Hopman; Benedetta Allegranzi; Shaheen Mehtar
Journal:  JAMA       Date:  2020-04-28       Impact factor: 56.272

Review 2.  Critical care and the global burden of critical illness in adults.

Authors:  Neill K J Adhikari; Robert A Fowler; Satish Bhagwanjee; Gordon D Rubenfeld
Journal:  Lancet       Date:  2010-10-11       Impact factor: 79.321

3.  The global need for essential emergency and critical care.

Authors:  Carl Otto Schell; Martin Gerdin Wärnberg; Anna Hvarfner; Andreas Höög; Ulrika Baker; Markus Castegren; Tim Baker
Journal:  Crit Care       Date:  2018-10-29       Impact factor: 9.097

4.  Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention.

Authors:  Zunyou Wu; Jennifer M McGoogan
Journal:  JAMA       Date:  2020-04-07       Impact factor: 56.272

  4 in total
  32 in total

1.  The Impact of COVID-19 on Neck of Femur Fracture Care: A Major Trauma Centre Experience, United Kingdom.

Authors:  Jiang An Lim; Azeem Thahir; Vinayak Amar Korde; Matija Krkovic
Journal:  Arch Bone Jt Surg       Date:  2021-07

2.  Lessons from the frontline: Documenting the pandemic emergency care experience from the Pacific region - Infrastructure and equipment.

Authors:  Megan Cox; Deepak Sharma; Georgina Phillips; Rob Mitchell; Lisa-Maree Herron; Claire E Brolan; Gerard O'Reilly; Sarah Körver; Mangu Kendino; Penisimani Poloniati; Berlin Kafoa
Journal:  Lancet Reg Health West Pac       Date:  2022-07-06

Review 3.  Lessons from the frontline: Documenting the experiences of Pacific emergency care clinicians responding to the COVID-19 pandemic.

Authors:  Megan Cox; Georgina Phillips; Rob Mitchell; Lisa-Maree Herron; Sarah Körver; Deepak Sharma; Claire E Brolan; Mangu Kendino; Osea K Masilaca; Gerard O'Reilly; Penisimani Poloniati; Berlin Kafoa
Journal:  Lancet Reg Health West Pac       Date:  2022-07-07

4.  Lessons from the frontline: The value of emergency care processes and data to pandemic responses across the Pacific region.

Authors:  Rob Mitchell; Gerard O'Reilly; Lisa-Maree Herron; Georgina Phillips; Deepak Sharma; Claire E Brolan; Sarah Körver; Mangu Kendino; Penisimani Poloniati; Berlin Kafoa; Megan Cox
Journal:  Lancet Reg Health West Pac       Date:  2022-07-06

Review 5.  Management of hip fracture in COVID-19 infected patients.

Authors:  Hao-Cheng Qin; Zhong He; Zhi-Wen Luo; Yu-Lian Zhu
Journal:  World J Orthop       Date:  2022-06-18

6.  Ethical issues in managing the COVID-19 pandemic.

Authors:  Kasper Raus; Eric Mortier; Kristof Eeckloo
Journal:  Bioethics       Date:  2021-05-05       Impact factor: 2.512

7.  Pulse oximetry in low-resource settings during the COVID-19 pandemic.

Authors:  Nichole Starr; Daniela Rebollo; Yohannes Molla Asemu; Leulayehu Akalu; Hanan Ali Mohammed; Misrak Woldeyohannes Menchamo; Eyayelem Melese; Senait Bitew; Iain Wilson; Mahelet Tadesse; Thomas G Weiser
Journal:  Lancet Glob Health       Date:  2020-07-03       Impact factor: 26.763

8.  Stroke Patients' Characteristics and Clinical Outcomes: A Pre-Post COVID-19 Comparison Study.

Authors:  Hong Chuan Loh; Kar Keong Neoh; Angelina Siing Ngi Tang; Chen Joo Chin; Purnima Devi Suppiah; Irene Looi; Khang Wen Goh; Ching Siang Tan; Long Chiau Ming
Journal:  Medicina (Kaunas)       Date:  2021-05-19       Impact factor: 2.430

9.  Oxygen systems and quality of care for children with pneumonia, malaria and diarrhoea: Analysis of a stepped-wedge trial in Nigeria.

Authors:  Hamish R Graham; Jaclyn Maher; Ayobami A Bakare; Cattram D Nguyen; Adejumoke I Ayede; Oladapo B Oyewole; Amy Gray; Rasa Izadnegahdar; Trevor Duke; Adegoke G Falade
Journal:  PLoS One       Date:  2021-07-08       Impact factor: 3.240

10.  An appeal for practical social justice in the COVID-19 global response in low-income and middle-income countries.

Authors:  Maureen Kelley; Rashida A Ferrand; Kui Muraya; Simukai Chigudu; Sassy Molyneux; Madhukar Pai; Edwine Barasa
Journal:  Lancet Glob Health       Date:  2020-05-14       Impact factor: 26.763

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