Tim Baker1, Carl Otto Schell2, Dan Brun Petersen3, Hendry Sawe4, Karima Khalid5, Samson Mndolo6, Jamie Rylance7, Daniel F McAuley8, Nobhojit Roy9, John Marshall10, Lee Wallis11, Elizabeth Molyneux12. 1. Muhimbili University of Health and Allied Sciences, Dar es Salaam, PO Box 65001, Tanzania; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden; Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden. Electronic address: tim.baker@ki.se. 2. Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden; Centre for Clinical Research Sörmland, Uppsala University, Eskilstuna, Sweden; Department of Internal Medicine, Nyköping Hospital, Sörmland Region, Nyköping, Sweden. 3. Ministry of Health, Community Development, Gender, Elderly and Children, Dodoma, Tanzania; Department of Emergency Medicine, Zealand University Hospital, Køge, Denmark. 4. Muhimbili University of Health and Allied Sciences, Dar es Salaam, PO Box 65001, Tanzania. 5. Muhimbili University of Health and Allied Sciences, Dar es Salaam, PO Box 65001, Tanzania; Muhimbili Orthopaedic Institute, Dar es Salaam, Tanzania. 6. Queen Elizabeth Central Hospital, Blantyre, Malawi. 7. Malawi Liverpool Wellcome Trust, Blantyre, Malawi. 8. Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK; Regional Intensive Care Unit, Royal Victoria Hospital, Belfast, UK. 9. Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden; Surgical Unit, WHO Collaborating Centre for Research on Surgical Care Delivery in LMICs, BARC Hospital (Government of India), Mumbai, India. 10. Interdepartmental Division of Critical Care Medicine, Department of Surgery, University of Toronto, Toronto, ON, Canada; International Forum for Acute Care Trialists, Toronto, ON, Canada. 11. Division of Emergency Medicine, University of Cape Town, Rondebosch, South Africa. 12. Queen Elizabeth Central Hospital, Blantyre, Malawi; University of Malawi College of Medicine, Blantyre, Malawi.
The coronavirus disease 2019 (COVID-19) pandemic will have a large impact in low-resource settings (LRS). 20% of COVID-19patients become critically ill with hypoxia or respiratory failure (figure
). Critical illness, describing any acute life-threatening condition, is receiving increased attention in global health because of its large disease burden and population impact. Before the COVID-19 pandemic, growing evidence suggested that the care of critical illness was overlooked in LRS—hospitals cannot, or do not, prioritise emergency and critical care. Most critically illpatients are cared for in emergency units and general wards and do not have access to advanced care in intensive care units (ICUs). Data from hospital wards in Malawi showed that 89% of hypoxicpatients (oxygen saturation <90%) were not receiving oxygen, and 53% of unconscious patients (Glasgow Coma Scale <9) were being nursed supine without a protected airway (unpublished data).
Figure
Severity profile of coronavirus disease 2019
Data source: Wu et al (2020).
Severity profile of coronavirus disease 2019Data source: Wu et al (2020).The COVID-19 pandemic will lead to a surge in the number of critically illpatients. Hospitals throughout the world will become overwhelmed, and care will be provided at a lower resource level than usual. Along with preventive measures and infection control, the clinical care of these patients will be a fundamental determinant of the pandemic's overall impact.Unfortunately, the headline figures of ICU requirements for COVID-19patients in resource-rich settings are masking the need for essential care. Attention is directed towards expensive, high-tech equipment that demands highly trained providers while neglecting low-cost essential care.To avoid this neglect, we recommend a primary policy focus on basic, effective actions with potential population impact. A conceptual framework has recently been proposed that illustrates the need for hospital readiness and good quality clinical practice for the dual aspects of identification and care of critically illpatients (appendix). Hospitals should establish effective systems for triage and essential care in emergency units and wards, including patient separation and staff safety. User-friendly, concise protocols should be developed, disseminated, and implemented for good quality and feasible clinical care, with WHO's leadership and through national authorities. Simple physiological signs have been shown to identify critical illness, and single-parameter systems might be easier to use than compound scores. The central role of oxygen therapy should be emphasised, oxygen supplies and delivery systems secured, and guidelines for sustainable and appropriate use issued. Other essential care includes a head-up patient position, suction, and simple chest physiotherapy. When human resources are limited, such care can be implemented by less trained health workers or vital-signs assistants through a protocolised approach and task sharing.Quality essential care of critical illness could have a large positive effect on mortality even without ICUs. It would ameliorate the fatalism and passivity that arises from an absence of high-resource treatment options. Moreover, provision of essential care could prevent progression to multi-organ failure, reducing the burden on limited ICU capacity. The ability of health services in LRS and throughout the world to provide good quality essential care of critical illness must be greatly and urgently increased.
Authors: Carl Otto Schell; Martin Gerdin Wärnberg; Anna Hvarfner; Andreas Höög; Ulrika Baker; Markus Castegren; Tim Baker Journal: Crit Care Date: 2018-10-29 Impact factor: 9.097
Authors: Megan Cox; Georgina Phillips; Rob Mitchell; Lisa-Maree Herron; Sarah Körver; Deepak Sharma; Claire E Brolan; Mangu Kendino; Osea K Masilaca; Gerard O'Reilly; Penisimani Poloniati; Berlin Kafoa Journal: Lancet Reg Health West Pac Date: 2022-07-07
Authors: Hamish R Graham; Jaclyn Maher; Ayobami A Bakare; Cattram D Nguyen; Adejumoke I Ayede; Oladapo B Oyewole; Amy Gray; Rasa Izadnegahdar; Trevor Duke; Adegoke G Falade Journal: PLoS One Date: 2021-07-08 Impact factor: 3.240