| Literature DB >> 32242929 |
Diana Oliveira1, Janaki Srinivasan2, Daniel Espino1, Keith Buchan3, Dana Dawson4, Duncan Shepherd1.
Abstract
The mitral valve is a complex anatomical structure whose physiological functioning relies on the biomechanical properties and structural integrity of its components. Their compromise can lead to mitral valve dysfunction, associated with morbidity and mortality. Therefore, a review on the morphometry of the mitral valve is crucial, more specifically on the importance of valve dimensions and shape for its function. This review initially provides a brief background on the anatomy and physiology of the mitral valve, followed by an analysis of the morphological information available. A characterisation of mathematical descriptions of several parts of the valve is performed and the impact of different dimensions and shape changes in disease is then outlined. Finally, a section regarding future directions and recommendations for the use of morphometric information in clinical analysis of the mitral valve is presented.Entities:
Keywords: biomechanics; computational anatomy; mitral valve; mitral valve disease; morphology analysis
Mesh:
Year: 2020 PMID: 32242929 PMCID: PMC7369193 DOI: 10.1111/joa.13196
Source DB: PubMed Journal: J Anat ISSN: 0021-8782 Impact factor: 2.921