Literature DB >> 32239984

A consistent skin care regimen leads to objective and subjective improvements in dry human skin: investigator-blinded randomized clinical trial.

Sooyoung Kim1,2, Baochau K Ly1, Judy H Ha3, Kathryn A Carson3, Stacy Hawkins4, Sewon Kang1, Anna L Chien1.   

Abstract

BACKGROUND: Dry, itchy skin can lower quality of life (QoL) and aggravate skin diseases. Moisturizing skin care products can have beneficial effects on dry skin. However, the role of a daily skin care routine is understudied.
OBJECTIVE: To understand how daily skin care with a mild cleanser and moisturizer impacts skin health and patients' QoL, in dry skin population.
METHODS: A randomized, investigator-blinded study of 52 participants with moderate to severe dry skin. The treatment group (n = 39) used mild cleanser and moisturizer twice daily for two weeks whereas the control group (n = 13) used mild cleanser without moisturizer. Total Clinical Score (TCS; erythema, scale and fissures), Visual Dryness Score (VDS) and subjective itch-related quality of life (ItchyQoL) were collected.
RESULTS: The treatment group showed significantly more improvement in TCS and VDS compared to the control group after two weeks. Among the three components of the ItchyQoL (symptoms, functioning, and emotions), symptom showed significantly greater improvement in the treatment compared to the control group. Over 80% of participants in the treatment group agreed that the regimen led to decrease in dryness/pruritus and improved skin texture.
CONCLUSIONS: A consistent skin care regimen should be an integral component of management of dry skin.

Entities:  

Keywords:  Dry skin; atopic dermatitis; moisturizer; pruritus; quality of life; xerosis

Mesh:

Substances:

Year:  2021        PMID: 32239984      PMCID: PMC7529700          DOI: 10.1080/09546634.2020.1751037

Source DB:  PubMed          Journal:  J Dermatolog Treat        ISSN: 0954-6634            Impact factor:   3.359


  30 in total

1.  Do moisturizers work?

Authors:  M Lodén
Journal:  J Cosmet Dermatol       Date:  2003-07       Impact factor: 2.696

Review 2.  Maintaining skin integrity in the aged: a systematic review.

Authors:  J Kottner; A Lichterfeld; U Blume-Peytavi
Journal:  Br J Dermatol       Date:  2013-09       Impact factor: 9.302

3.  Water modulation of stratum corneum chymotryptic enzyme activity and desquamation.

Authors:  A Watkinson; C Harding; A Moore; P Coan
Journal:  Arch Dermatol Res       Date:  2001-09       Impact factor: 3.017

4.  The course of chronic itch in hemodialysis patients: results of a 4-year follow-up study of GEHIS (German Epidemiological Hemodialysis Itch Study).

Authors:  N Plewig; R Ofenloch; T Mettang; E Weisshaar
Journal:  J Eur Acad Dermatol Venereol       Date:  2019-03-05       Impact factor: 6.166

5.  Cross-European validation of the ItchyQoL in pruritic dermatoses.

Authors:  C Zeidler; S Steinke; C Riepe; P Bruland; I Soto-Rey; M Storck; S Garcovich; C Blome; S Bobko; F J Legat; N Potekaev; A Lvov; L Misery; W Weger; A Reich; E Şavk; M Streit; E Serra-Baldrich; J C Szepietowski; G Yosipovitch; S C Chen; M Dugas; S Ständer
Journal:  J Eur Acad Dermatol Venereol       Date:  2018-09-25       Impact factor: 6.166

6.  Improvement of skin barrier function in atopic dermatitis patients with a new moisturizer containing a ceramide precursor.

Authors:  Eric Simpson; Arne Böhling; Stephan Bielfeldt; Catherine Bosc; Nabil Kerrouche
Journal:  J Dermatolog Treat       Date:  2012-09-19       Impact factor: 3.359

7.  A daily skincare regimen with a unique ceramide and filaggrin formulation rapidly improves chronic xerosis, pruritus, and quality of life in older adults.

Authors:  Anne Lynn S Chang; Suephy C Chen; Lars Osterberg; Staci Brandt; Erika C von Grote; Matthew H Meckfessel
Journal:  Geriatr Nurs       Date:  2017-06-07       Impact factor: 2.361

8.  Changes in skin barrier function following long-term treatment with moisturizers, a randomized controlled trial.

Authors:  I Buraczewska; B Berne; M Lindberg; H Törmä; M Lodén
Journal:  Br J Dermatol       Date:  2007-03       Impact factor: 9.302

Review 9.  Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders.

Authors:  Marie Lodén
Journal:  Am J Clin Dermatol       Date:  2003       Impact factor: 7.403

10.  Common pitfalls in statistical analysis: Intention-to-treat versus per-protocol analysis.

Authors:  Priya Ranganathan; C S Pramesh; Rakesh Aggarwal
Journal:  Perspect Clin Res       Date:  2016 Jul-Sep
View more
  2 in total

Review 1.  Itch in the era of COVID-19 pandemic: An unfolding scenario.

Authors:  Aleksandra A Stefaniak; Rafał Białynicki-Birula; Piotr K Krajewski; Łukasz Matusiak; Mohamad Goldust; Jacek C Szepietowski
Journal:  Dermatol Ther       Date:  2020-05-27       Impact factor: 2.851

2.  Increased Prevalence of Face Mask-Induced Itch in Health Care Workers.

Authors:  Piotr K Krajewski; Łukasz Matusiak; Marta Szepietowska; Rafał Białynicki-Birula; Jacek C Szepietowski
Journal:  Biology (Basel)       Date:  2020-12-07
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.