Literature DB >> 28600081

A daily skincare regimen with a unique ceramide and filaggrin formulation rapidly improves chronic xerosis, pruritus, and quality of life in older adults.

Anne Lynn S Chang1, Suephy C Chen2, Lars Osterberg3, Staci Brandt4, Erika C von Grote5, Matthew H Meckfessel6.   

Abstract

A skin care regimen which significantly improved atopic dermatitis and pruritus was evaluated for its efficacy and acceptability in senior subjects diagnosed with xerosis who also suffer from pruritus. This was an open-label, single-center study, designed to evaluate the daily use of a skin care regimen for 15 days. Assessments were made at baseline, day 8 and day 15 for visual skin dryness, transepidermal water loss (TEWL), hydration, desquamation, subject-perceived itch and quality of life (QoL). Twenty-five subjects, ages 60-73 years, had significantly improved skin visual dryness, hydration, desquamation, itch and QoL at days 8 and 15, relative to baseline (P < .05). TEWL was improved, though not significantly. Subjects expressed a high degree of satisfaction with the results. This regimen provides geriatric patients with an easily incorporated skin routine to help improve a common symptom of aging skin which negatively affects QoL.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Pruritus; Quality of life; Senior skin care; Xerosis

Mesh:

Substances:

Year:  2017        PMID: 28600081     DOI: 10.1016/j.gerinurse.2017.05.002

Source DB:  PubMed          Journal:  Geriatr Nurs        ISSN: 0197-4572            Impact factor:   2.361


  5 in total

1.  Exogenous Ceramide Serves as a Precursor to Endogenous Ceramide Synthesis and as a Modulator of Keratinocyte Differentiation.

Authors:  Kyong-Oh Shin; Hisashi Mihara; Kenya Ishida; Yoshikazu Uchida; Kyungho Park
Journal:  Cells       Date:  2022-05-25       Impact factor: 7.666

2.  Dry skin and the use of leave-on products in nursing care: A prevalence study in nursing homes and hospitals.

Authors:  Anna Lechner; Nils Lahmann; Andrea Lichterfeld-Kottner; Ursula Müller-Werdan; Ulrike Blume-Peytavi; Jan Kottner
Journal:  Nurs Open       Date:  2018-09-27

Review 3.  Breaking the Itch-Scratch Cycle: Topical Options for the Management of Chronic Cutaneous Itch in Atopic Dermatitis.

Authors:  Ian P Harrison; Fabrizio Spada
Journal:  Medicines (Basel)       Date:  2019-07-18

4.  A consistent skin care regimen leads to objective and subjective improvements in dry human skin: investigator-blinded randomized clinical trial.

Authors:  Sooyoung Kim; Baochau K Ly; Judy H Ha; Kathryn A Carson; Stacy Hawkins; Sewon Kang; Anna L Chien
Journal:  J Dermatolog Treat       Date:  2021-06-22       Impact factor: 3.359

5.  Sujiaonori-Derived Algal Biomaterials Inhibit Allergic Reaction in Allergen-Sensitized RBL-2H3 Cell Line and Improve Skin Health in Humans.

Authors:  Nlandu Roger Ngatu; Mamoru Tanaka; Mitsunori Ikeda; Masataka Inoue; Sakiko Kanbara; Sayumi Nojima
Journal:  J Funct Biomater       Date:  2017-08-29
  5 in total

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