Literature DB >> 3223989

ADP-ribosyl proteins formed by pertussis toxin are specifically cleaved by mercury ions.

T Meyer1, R Koch, W Fanick, H Hilz.   

Abstract

Various types of ADP-ribosyl protein conjugates were synthesized and their chemical stability was compared with that of cysteine-linked ADP-ribosyl groups as formed by incubation of transducin or Gi/Go proteins with NAD and pertussis toxin. Treatment with 0.1 mM HgCl2 specifically cleaved the cysteine-linked conjugates. This may provide a tool for the quantitation of modified Gi/Go proteins as well as of other acceptors modified by ADP-ribose at cysteine residues in the presence of other ADP-ribosyl proteins.

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Year:  1988        PMID： 3223989     DOI： 10.1515/bchm3.1988.369.2.579

Source DB:  PubMed          Journal:  Biol Chem Hoppe Seyler        ISSN： 0177-3593


  12 in total

1.  Nitric oxide stimulates the ADP-ribosylation of a 41-kDa cytosolic protein in Dictyostelium discoideum.

Authors:  Y Tao; A Howlett; C Klein
Journal:  Proc Natl Acad Sci U S A       Date:  1992-07-01       Impact factor: 11.205

Review 2.  Clostridial ADP-ribosyltransferases--modification of low molecular weight GTP-binding proteins and of actin by clostridial toxins.

Authors:  K Aktories
Journal:  Med Microbiol Immunol       Date:  1990       Impact factor: 3.402

Review 3.  Enzymatic and nonenzymatic ADP-ribosylation of cysteine.

Authors:  L J McDonald; J Moss
Journal:  Mol Cell Biochem       Date:  1994-09       Impact factor: 3.396

4.  Purification of a novel G-protein alpha 0-subtype from mammalian brain.

Authors:  B Nürnberg; K Spicher; R Harhammer; A Bosserhoff; R Frank; H Hilz; G Schultz
Journal:  Biochem J       Date:  1994-06-01       Impact factor: 3.857

5.  Localization and partial characterization of ADP-ribosylation products in hearts from adult and neonatal rats.

Authors:  K J Piron; K K McMahon
Journal:  Biochem J       Date:  1990-09-15       Impact factor: 3.857

6.  ADP-ribosylation of Drosophila indirect-flight-muscle actin and arthrin by Clostridium botulinum C2 toxin and Clostridium perfringens iota toxin.

Authors:  I Just; E S Hennessey; D R Drummond; K Aktories; J C Sparrow
Journal:  Biochem J       Date:  1993-04-15       Impact factor: 3.857

7.  Stimulation by nitric oxide of an NAD linkage to glyceraldehyde-3-phosphate dehydrogenase.

Authors:  L J McDonald; J Moss
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-01       Impact factor: 11.205

Review 8.  Nitric oxide and NAD-dependent protein modification.

Authors:  L J McDonald; J Moss
Journal:  Mol Cell Biochem       Date:  1994-09       Impact factor: 3.396

9.  Inactivation of the elongation factor Tu by mosquitocidal toxin-catalyzed mono-ADP-ribosylation.

Authors:  Jörg Schirmer; Hans-Joachim Wieden; Marina V Rodnina; Klaus Aktories
Journal:  Appl Environ Microbiol       Date:  2002-10       Impact factor: 4.792

10.  ADP-ribosylation of an approximately 70-kilodalton protein of Klebsiella pneumoniae.

Authors:  U Geipel; I Just; K Aktories
Journal:  Infect Immun       Date:  1996-05       Impact factor: 3.441
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