Literature DB >> 1352880

Nitric oxide stimulates the ADP-ribosylation of a 41-kDa cytosolic protein in Dictyostelium discoideum.

Y Tao1, A Howlett, C Klein.   

Abstract

Nitric oxide-releasing compounds were shown to activate an ADP-ribosyltransferase activity in the cytosol of Dictyostelium discoideum. The enzyme ADP-ribosylated a cytosolic protein of approximately 41 kDa, p41. Neither cGMP nor GTP and its analogues affected this ADP-ribosylation. p41 differs from other substrates ADP-ribosylated by cholera, pertussis, or diphtheria toxins. Treatment of ADP-ribosylated p41 with snake venom phosphodiesterase released adenosine 5'-monophosphate, indicating a mono-ADP-ribose-protein linkage. This linkage was stable to neutral hydroxylamine but was sensitive to mercury ions and iodomethane, suggesting an attachment to a cysteine residue. Treatment of intact cells with nitric oxide-releasing compounds appeared to stimulate the ADP-ribosylation of p41 and this modification was reversible.

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Year:  1992        PMID： 1352880      PMCID： PMC49405          DOI： 10.1073/pnas.89.13.5902

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  44 in total

1.  Reversible ADP-ribosylation of the 78 kDa glucose-regulated protein.

Authors:  G H Leno; B E Ledford
Journal:  FEBS Lett       Date:  1990-12-10       Impact factor: 4.124

2.  Endogenous ADP-ribosylation of elongation factor 2 in polyoma virus-transformed baby hamster kidney cells.

Authors:  J L Fendrick; W J Iglewski
Journal:  Proc Natl Acad Sci U S A       Date:  1989-01       Impact factor: 11.205

3.  Involvement of Gi in the inhibition of adenylate cyclase by cannabimimetic drugs.

Authors:  A C Howlett; J M Qualy; L L Khachatrian
Journal:  Mol Pharmacol       Date:  1986-03       Impact factor: 4.436

4.  Immunological and biochemical differentiation of guanyl nucleotide binding proteins: interaction of Go alpha with rhodopsin, anti-Go alpha polyclonal antibodies, and a monoclonal antibody against transducin alpha subunit and Gi alpha.

Authors:  S C Tsai; R Adamik; Y Kanaho; J L Halpern; J Moss
Journal:  Biochemistry       Date:  1987-07-28       Impact factor: 3.162

5.  Activation of a cytosolic ADP-ribosyltransferase by nitric oxide-generating agents.

Authors:  B Brüne; E G Lapetina
Journal:  J Biol Chem       Date:  1989-05-25       Impact factor: 5.157

6.  Regulation of Dictyostelium discoideum adenylate cyclase by manganese and adenosine analogs.

Authors:  L Khachatrian; C Klein; A Howlett
Journal:  Biochim Biophys Acta       Date:  1987-02-18

Review 7.  Nitric oxide: biosynthesis and biological significance.

Authors:  M A Marletta
Journal:  Trends Biochem Sci       Date:  1989-12       Impact factor: 13.807

8.  Reversibility of arginine-specific mono(ADP-ribosyl)ation: identification in erythrocytes of an ADP-ribose-L-arginine cleavage enzyme.

Authors:  J Moss; M K Jacobson; S J Stanley
Journal:  Proc Natl Acad Sci U S A       Date:  1985-09       Impact factor: 11.205

9.  Pertussis and cholera toxin ADP-ribosylation in Dictyostelium discoideum membranes.

Authors:  L Khachatrian; C Klein; A Howlett
Journal:  Biochem Biophys Res Commun       Date:  1987-12-31       Impact factor: 3.575

10.  L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.

Authors:  J B Hibbs; Z Vavrin; R R Taintor
Journal:  J Immunol       Date:  1987-01-15       Impact factor: 5.422
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  5 in total

1.  Developmental and biochemical characteristics of the cardiac membrane-bound arginine-specific mono-ADP-ribosyltransferase.

Authors:  K K McMahon; K J Piron; V T Ha; A T Fullerton
Journal:  Biochem J       Date:  1993-08-01       Impact factor: 3.857

2.  Stimulation by nitric oxide of an NAD linkage to glyceraldehyde-3-phosphate dehydrogenase.

Authors:  L J McDonald; J Moss
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-01       Impact factor: 11.205

Review 3.  Nitric oxide and NAD-dependent protein modification.

Authors:  L J McDonald; J Moss
Journal:  Mol Cell Biochem       Date:  1994-09       Impact factor: 3.396

Review 4.  Cytokinins in Dictyostelia - A Unique Model for Studying the Functions of Signaling Agents From Species to Kingdoms.

Authors:  Megan M Aoki; R J Neil Emery; Christophe Anjard; Craig R Brunetti; Robert J Huber
Journal:  Front Cell Dev Biol       Date:  2020-06-19

5.  Detection and characterisation of NAD(P)H-diaphorase activity in Dictyostelium discoideum cells (Protozoa).

Authors:  A Amaroli; M G Chessa
Journal:  Eur J Histochem       Date:  2012-10-29       Impact factor: 3.188
  5 in total

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