Literature DB >> 32234940

Upfront Surgery for Small Intestinal Non-Hodgkin's Lymphoma.

Tetsuhiro Iida1, Hiroaki Nozawa2, Hirofumi Sonoda2, Kazuhiro Toyama3, Kazushige Kawai2, Keisuke Hata2, Toshiaki Tanaka2, Takeshi Nishikawa2, Kazuhito Sasaki2, Yasutaka Shuno2, Manabu Kaneko2, Koji Murono2, Shigenobu Emoto2, Hiroaki Ishii2, Mineo Kurokawa3, Soichiro Ishihara2.   

Abstract

BACKGROUND/AIM: The clinical significance of surgery for secondary small intestinal non-Hodgkin's lymphomas (NHL) remains unknown. This study aimed to investigate the efficacy of resection for both primary and secondary small intestinal NHL. PATIENTS AND METHODS: Twenty patients with small intestinal lymphoma who underwent surgical resection at our Institute between 2009 and 2017 were retrospectively evaluated. The clinicopathological and surgery-related factors were reviewed. We also analyzed their surgical outcomes such as postoperative complications, perforation rate, and overall survival (OS).
RESULTS: In total, 13 (65%) and 7 (35%) patients had primary and secondary lymphomas, respectively. A total of 70% of patients were diagnosed with aggressive-type lymphomas. A total of 15 (75%) patients had Lugano system stage IV. Only one (5%) patient experienced postoperative grade II deep vein thrombosis and pulmonary embolism. The 3-year OS rate after surgery was 59.6%.
CONCLUSION: Surgical resection prior to chemotherapy is a feasible and safe therapeutic strategy for small intestinal NHL. Copyright
© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Small intestinal lymphoma; prevention of perforation

Mesh:

Year:  2020        PMID: 32234940     DOI: 10.21873/anticanres.14206

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  3 in total

1.  Surgery plus chemotherapy versus chemotherapy alone in primary intestinal lymphoma: a meta-analysis.

Authors:  Yefei Shu; Xiaofeng Xu; Wei Yang; Ling Xu
Journal:  J Int Med Res       Date:  2021-11       Impact factor: 1.671

2.  The impact of surgery on long-term survival of patients with primary intestinal non-Hodgkin lymphomas based on SEER database.

Authors:  Cuifen Zhang; Xiaohong Zhang; Zeyu Liu; Jiahao Tao; Lizhu Lin; Linzhu Zhai
Journal:  Sci Rep       Date:  2021-11-29       Impact factor: 4.379

3.  A visual model for prognostic estimation in patients with primary diffuse large B-cell lymphoma of small intestine and colon: analysis of 1,613 cases from the SEER database.

Authors:  Yang Wang; Jia Song; Shupeng Wen; Xiaolan Zhang
Journal:  Transl Cancer Res       Date:  2021-04       Impact factor: 1.241

  3 in total

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