| Literature DB >> 32227197 |
Bradley Sanville1, Rebecca Corbett1, Wesley Pidcock1, Kaitlyn Hardin2, Christian Sebat1, Minh-Vu Nguyen2, George R Thompson2, Angela Haczku1, Michael Schivo1, Stuart Cohen2.
Abstract
This is the first known community transmission case of the novel coronavirus disease (COVID-19) in the United States, with significant public health implications. Diagnosis of COVID-19 is currently confirmed with PCR based testing of appropriate respiratory samples. Given the absence of travel or known exposure history, this patient did not meet the criteria for testing according to CDC guidelines at the time of her presentation. Since this case, any patient with severe disease (eg, ARDS or pneumonia) requiring hospitalization without an explanatory diagnosis can be tested even if no clear source of exposure is identified. While influencing national health policies for revising screening criteria, this case also highlighted significant knowledge gaps in diagnosis and treatment and a desperate need for early, widespread, fast and cheap testing for COVID-19.Entities:
Keywords: COVID-19; SARS-CoV-2; community transmission; index case; novel coronavirus
Mesh:
Substances:
Year: 2020 PMID: 32227197 PMCID: PMC7197621 DOI: 10.1093/cid/ciaa347
Source DB: PubMed Journal: Clin Infect Dis ISSN: 1058-4838 Impact factor: 9.079