Sangshin Park1,2,3, Christina E Nixon1,4, Olivia Miller5, Nam-Kyong Choi6, Jonathan D Kurtis1,4, Jennifer F Friedman1,2, Ian C Michelow1,2. 1. Center for International Health Research, Rhode Island Hospital, Providence, Rhode Island, USA. 2. Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA. 3. Graduate School of Urban Public Health, University of Seoul, Seoul, Republic of Korea. 4. Department of Pathology and Laboratory Medicine, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA. 5. Department of Global Health, DePauw University, Greencastle, Indiana, USA. 6. Department of Health Convergence, Ewha Womans University, Seoul, Republic of Korea.
Abstract
BACKGROUND: Our objective was to quantify the risk of acquiring malaria among progeny of women with malaria during pregnancy. METHODS: We searched MEDLINE, EMBASE, CINAHL, and the Cochrane Library for eligible prospective studies. The primary predictor was malaria during pregnancy defined as placental malaria, parasitemia, clinical malaria, or pregnancy-associated malaria. Primary outcomes were parasitemia or clinically defined malaria of young children. We performed meta-analyses to pool adjusted risk estimates using a random-effects model. RESULTS: Nineteen of 2053 eligible studies met inclusion criteria for the systemic review. Eleven of these studies were quantitative and were included in the meta-analyses. The pooled adjusted odds ratio (aOR) or adjusted hazard ratio (aHR) of malaria during pregnancy for detection of parasitemia in young children were 1.94 (95% confidence interval [CI], 0.93-4.07; P = .08) and 1.46 (95% CI, 1.07-2.00; P < .001), respectively. The pooled aOR or aHR for clinically defined malaria in young children were 2.82 (95% CI, 1.82-4.38; P < .001) and 1.31 (95% CI, 0.96-1.79; P = .09), respectively. CONCLUSIONS: Our results confirmed that malaria during pregnancy significantly increased the overall risk of malaria in young children via indeterminate mechanisms and emphasize the urgent need to implement safe and highly effective strategies to prevent malaria during pregnancy.
BACKGROUND: Our objective was to quantify the risk of acquiring malaria among progeny of women with malaria during pregnancy. METHODS: We searched MEDLINE, EMBASE, CINAHL, and the Cochrane Library for eligible prospective studies. The primary predictor was malaria during pregnancy defined as placental malaria, parasitemia, clinical malaria, or pregnancy-associated malaria. Primary outcomes were parasitemia or clinically defined malaria of young children. We performed meta-analyses to pool adjusted risk estimates using a random-effects model. RESULTS: Nineteen of 2053 eligible studies met inclusion criteria for the systemic review. Eleven of these studies were quantitative and were included in the meta-analyses. The pooled adjusted odds ratio (aOR) or adjusted hazard ratio (aHR) of malaria during pregnancy for detection of parasitemia in young children were 1.94 (95% confidence interval [CI], 0.93-4.07; P = .08) and 1.46 (95% CI, 1.07-2.00; P < .001), respectively. The pooled aOR or aHR for clinically defined malaria in young children were 2.82 (95% CI, 1.82-4.38; P < .001) and 1.31 (95% CI, 0.96-1.79; P = .09), respectively. CONCLUSIONS: Our results confirmed that malaria during pregnancy significantly increased the overall risk of malaria in young children via indeterminate mechanisms and emphasize the urgent need to implement safe and highly effective strategies to prevent malaria during pregnancy.
Authors: Stephen J Rogerson; Meghna Desai; Alfredo Mayor; Elisa Sicuri; Steve M Taylor; Anna M van Eijk Journal: Lancet Infect Dis Date: 2018-01-31 Impact factor: 25.071
Authors: Jonathan D Kurtis; Dipak K Raj; Ian C Michelow; Sangshin Park; Christina E Nixon; Emily A McDonald; Christian P Nixon; Sunthorn Pond-Tor; Ambrish Jha; Ross J Taliano; Edward R Kabyemela; Jennifer F Friedman; Patrick E Duffy; Michal Fried Journal: Clin Infect Dis Date: 2019-05-02 Impact factor: 9.079
Authors: Agnès Le Port; Laurence Watier; Gilles Cottrell; Smaila Ouédraogo; Célia Dechavanne; Charlotte Pierrat; Antoine Rachas; Julie Bouscaillou; Aziz Bouraima; Achille Massougbodji; Benjamin Fayomi; Anne Thiébaut; Fabrice Chandre; Florence Migot-Nabias; Yves Martin-Prevel; André Garcia; Michel Cot Journal: PLoS One Date: 2011-11-11 Impact factor: 3.240
Authors: Samuel Tassi Yunga; Genevieve G Fouda; Grace Sama; Julia B Ngu; Rose G F Leke; Diane W Taylor Journal: Sci Rep Date: 2018-01-09 Impact factor: 4.379
Authors: Patrick G T Walker; Feiko O ter Kuile; Tini Garske; Clara Menendez; Azra C Ghani Journal: Lancet Glob Health Date: 2014-07-23 Impact factor: 26.763
Authors: Christopher J L Murray; Katrina F Ortblad; Caterina Guinovart; Stephen S Lim; Timothy M Wolock; D Allen Roberts; Emily A Dansereau; Nicholas Graetz; Ryan M Barber; Jonathan C Brown; Haidong Wang; Herbert C Duber; Mohsen Naghavi; Daniel Dicker; Lalit Dandona; Joshua A Salomon; Kyle R Heuton; Kyle Foreman; David E Phillips; Thomas D Fleming; Abraham D Flaxman; Bryan K Phillips; Elizabeth K Johnson; Megan S Coggeshall; Foad Abd-Allah; Semaw Ferede Abera; Jerry P Abraham; Ibrahim Abubakar; Laith J Abu-Raddad; Niveen Me Abu-Rmeileh; Tom Achoki; Austine Olufemi Adeyemo; Arsène Kouablan Adou; José C Adsuar; Emilie Elisabet Agardh; Dickens Akena; Mazin J Al Kahbouri; Deena Alasfoor; Mohammed I Albittar; Gabriel Alcalá-Cerra; Miguel Angel Alegretti; Zewdie Aderaw Alemu; Rafael Alfonso-Cristancho; Samia Alhabib; Raghib Ali; Francois Alla; Peter J Allen; Ubai Alsharif; Elena Alvarez; Nelson Alvis-Guzman; Adansi A Amankwaa; Azmeraw T Amare; Hassan Amini; Walid Ammar; Benjamin O Anderson; Carl Abelardo T Antonio; Palwasha Anwari; Johan Arnlöv; Valentina S Arsic Arsenijevic; Ali Artaman; Rana J Asghar; Reza Assadi; Lydia S Atkins; Alaa Badawi; Kalpana Balakrishnan; Amitava Banerjee; Sanjay Basu; Justin Beardsley; Tolesa Bekele; Michelle L Bell; Eduardo Bernabe; Tariku Jibat Beyene; Neeraj Bhala; Ashish Bhalla; Zulfiqar A Bhutta; Aref Bin Abdulhak; Agnes Binagwaho; Jed D Blore; Berrak Bora Basara; Dipan Bose; Michael Brainin; Nicholas Breitborde; Carlos A Castañeda-Orjuela; Ferrán Catalá-López; Vineet K Chadha; Jung-Chen Chang; Peggy Pei-Chia Chiang; Ting-Wu Chuang; Mercedes Colomar; Leslie Trumbull Cooper; Cyrus Cooper; Karen J Courville; Benjamin C Cowie; Michael H Criqui; Rakhi Dandona; Anand Dayama; Diego De Leo; Louisa Degenhardt; Borja Del Pozo-Cruz; Kebede Deribe; Don C Des Jarlais; Muluken Dessalegn; Samath D Dharmaratne; Uğur Dilmen; Eric L Ding; Tim R Driscoll; Adnan M Durrani; Richard G Ellenbogen; Sergey Petrovich Ermakov; Alireza Esteghamati; Emerito Jose A Faraon; Farshad Farzadfar; Seyed-Mohammad Fereshtehnejad; Daniel Obadare Fijabi; Mohammad H Forouzanfar; Urbano Fra Paleo; Lynne Gaffikin; Amiran Gamkrelidze; Fortuné Gbètoho Gankpé; Johanna M Geleijnse; Bradford D Gessner; Katherine B Gibney; Ibrahim Abdelmageem Mohamed Ginawi; Elizabeth L Glaser; Philimon Gona; Atsushi Goto; Hebe N Gouda; Harish Chander Gugnani; Rajeev Gupta; Rahul Gupta; Nima Hafezi-Nejad; Randah Ribhi Hamadeh; Mouhanad Hammami; Graeme J Hankey; Hilda L Harb; Josep Maria Haro; Rasmus Havmoeller; Simon I Hay; Mohammad T Hedayati; Ileana B Heredia Pi; Hans W Hoek; John C Hornberger; H Dean Hosgood; Peter J Hotez; Damian G Hoy; John J Huang; Kim M Iburg; Bulat T Idrisov; Kaire Innos; Kathryn H Jacobsen; Panniyammakal Jeemon; Paul N Jensen; Vivekanand Jha; Guohong Jiang; Jost B Jonas; Knud Juel; Haidong Kan; Ida Kankindi; Nadim E Karam; André Karch; Corine Kakizi Karema; Anil Kaul; Norito Kawakami; Dhruv S Kazi; Andrew H Kemp; Andre Pascal Kengne; Andre Keren; Maia Kereselidze; Yousef Saleh Khader; Shams Eldin Ali Hassan Khalifa; Ejaz Ahmed Khan; Young-Ho Khang; Irma Khonelidze; Yohannes Kinfu; Jonas M Kinge; Luke Knibbs; Yoshihiro Kokubo; S Kosen; Barthelemy Kuate Defo; Veena S Kulkarni; Chanda Kulkarni; Kaushalendra Kumar; Ravi B Kumar; G Anil Kumar; Gene F Kwan; Taavi Lai; Arjun Lakshmana Balaji; Hilton Lam; Qing Lan; Van C Lansingh; Heidi J Larson; Anders Larsson; Jong-Tae Lee; James Leigh; Mall Leinsalu; Ricky Leung; Yichong Li; Yongmei Li; Graça Maria Ferreira De Lima; Hsien-Ho Lin; Steven E Lipshultz; Shiwei Liu; Yang Liu; Belinda K Lloyd; Paulo A Lotufo; Vasco Manuel Pedro Machado; Jennifer H Maclachlan; Carlos Magis-Rodriguez; Marek Majdan; Christopher Chabila Mapoma; Wagner Marcenes; Melvin Barrientos Marzan; Joseph R Masci; Mohammad Taufiq Mashal; Amanda J Mason-Jones; Bongani M Mayosi; Tasara T Mazorodze; Abigail Cecilia Mckay; Peter A Meaney; Man Mohan Mehndiratta; Fabiola Mejia-Rodriguez; Yohannes Adama Melaku; Ziad A Memish; Walter Mendoza; Ted R Miller; Edward J Mills; Karzan Abdulmuhsin Mohammad; Ali H Mokdad; Glen Liddell Mola; Lorenzo Monasta; Marcella Montico; Ami R Moore; Rintaro Mori; Wilkister Nyaora Moturi; Mitsuru Mukaigawara; Kinnari S Murthy; Aliya Naheed; Kovin S Naidoo; Luigi Naldi; Vinay Nangia; K M Venkat Narayan; Denis Nash; Chakib Nejjari; Robert G Nelson; Sudan Prasad Neupane; Charles R Newton; Marie Ng; Muhammad Imran Nisar; Sandra Nolte; Ole F Norheim; Vincent Nowaseb; Luke Nyakarahuka; In-Hwan Oh; Takayoshi Ohkubo; Bolajoko O Olusanya; Saad B Omer; John Nelson Opio; Orish Ebere Orisakwe; Jeyaraj D Pandian; Christina Papachristou; Angel J Paternina Caicedo; Scott B Patten; Vinod K Paul; Boris Igor Pavlin; Neil Pearce; David M Pereira; Aslam Pervaiz; Konrad Pesudovs; Max Petzold; Farshad Pourmalek; Dima Qato; Amado D Quezada; D Alex Quistberg; Anwar Rafay; Kazem Rahimi; Vafa Rahimi-Movaghar; Sajjad Ur Rahman; Murugesan Raju; Saleem M Rana; Homie Razavi; Robert Quentin Reilly; Giuseppe Remuzzi; Jan Hendrik Richardus; Luca Ronfani; Nobhojit Roy; Nsanzimana Sabin; Mohammad Yahya Saeedi; Mohammad Ali Sahraian; Genesis May J Samonte; Monika Sawhney; Ione J C Schneider; David C Schwebel; Soraya Seedat; Sadaf G Sepanlou; Edson E Servan-Mori; Sara Sheikhbahaei; Kenji Shibuya; Hwashin Hyun Shin; Ivy Shiue; Rupak Shivakoti; Inga Dora Sigfusdottir; Donald H Silberberg; Andrea P Silva; Edgar P Simard; Jasvinder A Singh; Vegard Skirbekk; Karen Sliwa; Samir Soneji; Sergey S Soshnikov; Chandrashekhar T Sreeramareddy; Vasiliki Kalliopi Stathopoulou; Konstantinos Stroumpoulis; Soumya Swaminathan; Bryan L Sykes; Karen M Tabb; Roberto Tchio Talongwa; Eric Yeboah Tenkorang; Abdullah Sulieman Terkawi; Alan J Thomson; Andrew L Thorne-Lyman; Jeffrey A Towbin; Jefferson Traebert; Bach X Tran; Zacharie Tsala Dimbuene; Miltiadis Tsilimbaris; Uche S Uchendu; Kingsley N Ukwaja; Selen Begüm Uzun; Andrew J Vallely; Tommi J Vasankari; N Venketasubramanian; Francesco S Violante; Vasiliy Victorovich Vlassov; Stein Emil Vollset; Stephen Waller; Mitchell T Wallin; Linhong Wang; XiaoRong Wang; Yanping Wang; Scott Weichenthal; Elisabete Weiderpass; Robert G Weintraub; Ronny Westerman; Richard A White; James D Wilkinson; Thomas Neil Williams; Solomon Meseret Woldeyohannes; John Q Wong; Gelin Xu; Yang C Yang; Yuichiro Yano; Gokalp Kadri Yentur; Paul Yip; Naohiro Yonemoto; Seok-Jun Yoon; Mustafa Younis; Chuanhua Yu; Kim Yun Jin; Maysaa El Sayed Zaki; Yong Zhao; Yingfeng Zheng; Maigeng Zhou; Jun Zhu; Xiao Nong Zou; Alan D Lopez; Theo Vos Journal: Lancet Date: 2014-07-22 Impact factor: 79.321
Authors: Abel Kakuru; Michelle E Roh; Richard Kajubi; Teddy Ochieng; John Ategeka; Harriet Ochokoru; Miriam Nakalembe; Tamara D Clark; Theodore Ruel; Sarah G Staedke; Daniel Chandramohan; Diane V Havlir; Moses R Kamya; Grant Dorsey; Prasanna Jagannathan Journal: Malar J Date: 2020-12-03 Impact factor: 2.979
Authors: Sabine Gies; Stephen A Roberts; Salou Diallo; Olga M Lompo; Halidou Tinto; Bernard J Brabin Journal: Matern Child Nutr Date: 2020-11-25 Impact factor: 3.092