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Literature DB >> 32211718

An implantable multifunctional neural microprobe for simultaneous multi-analyte sensing and chemical delivery.

Bo Wang¹, Ximiao Wen, Yan Cao, Shan Huang, Hoa A Lam, Tingyi Leo Liu, Pei-Shan Chung, Harold G Monbouquette, Pei-Yu Chiou, Nigel T Maidment.

Abstract

A multifunctional chemical neural probe fabrication process exploiting PDMS thin-film transfer to incorporate a microfluidic channel onto a silicon-based microelectrode array (MEA) platform, and enzyme microstamping to provide multi-analyte detection is described. The Si/PDMS hybrid chemtrode, modified with a nano-based on-probe IrOx reference electrode, was validated in brain phantoms and in rat brain.

Entities: Chemical Disease Gene Species

Year: 2020 PMID： 32211718 PMCID： PMC7192313 DOI： 10.1039/d0lc00021c

Source DB: PubMed Journal: Lab Chip ISSN： 1473-0189 Impact factor: 6.799

27 in total

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Journal: Colloids Surf B Biointerfaces Date: 2006-10-12 Impact factor: 5.268

3. Selective detection of extracellular glutamate in brain tissue using microelectrode arrays coated with over-oxidized polypyrrole.

Authors: Eric Walker; Jianjun Wang; Naser Hamdi; Harold G Monbouquette; Nigel T Maidment
Journal: Analyst Date: 2007-09-19 Impact factor: 4.616

4. Fabrication of 3D high aspect ratio PDMS microfluidic networks with a hybrid stamp.

Authors: Yu-Chun Kung; Kuo-Wei Huang; Yu-Jui Fan; Pei-Yu Chiou
Journal: Lab Chip Date: 2015-04-21 Impact factor: 6.799

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Journal: Neuropsychopharmacology Date: 1999-03 Impact factor: 7.853

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Authors: Sang Ho Ye; Junji Watanabe; Yasuhiko Iwasaki; Kazuhiko Ishihara
Journal: Biomaterials Date: 2003-10 Impact factor: 12.479

7. Electrochemically deposited iridium oxide reference electrode integrated with an electroenzymatic glutamate sensor on a multi-electrode array microprobe.

Authors: Vanessa M Tolosa; Kate M Wassum; Nigel T Maidment; Harold G Monbouquette
Journal: Biosens Bioelectron Date: 2012-11-06 Impact factor: 10.618

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Authors: S A Marzouk; S Ufer; R P Buck; T A Johnson; L A Dunlap; W E Cascio
Journal: Anal Chem Date: 1998-12-01 Impact factor: 6.986

9. Implantable Microprobe with Arrayed Microsensors for Combined Amperometric Monitoring of the Neurotransmitters, Glutamate and Dopamine.

Authors: Tina T-C Tseng; Harold G Monbouquette
Journal: J Electroanal Chem (Lausanne) Date: 2012-07-25 Impact factor: 4.464