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Literature DB >> 32200648

Harnessing the power of microscopy images to accelerate drug discovery: what are the possibilities?

Justin Boyd¹, Myles Fennell², Anne Carpenter³.

Abstract

Entities: Chemical Disease Gene Species

Mesh：

Year: 2020 PMID： 32200648 PMCID： PMC7521136 DOI： 10.1080/17460441.2020.1743675

Source DB: PubMed Journal: Expert Opin Drug Discov ISSN： 1746-0441 Impact factor: 6.098

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27 in total

1. Integrating high-content screening and ligand-target prediction to identify mechanism of action.

Authors: Daniel W Young; Andreas Bender; Jonathan Hoyt; Elizabeth McWhinnie; Gung-Wei Chirn; Charles Y Tao; John A Tallarico; Mark Labow; Jeremy L Jenkins; Timothy J Mitchison; Yan Feng
Journal: Nat Chem Biol Date: 2007-12-09 Impact factor: 15.040

Review 2. High-Throughput Imaging for the Discovery of Cellular Mechanisms of Disease.

Authors: Gianluca Pegoraro; Tom Misteli
Journal: Trends Genet Date: 2017-07-18 Impact factor: 11.639

3. Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling.

Authors: Mathias J Wawer; Kejie Li; Sigrun M Gustafsdottir; Vebjorn Ljosa; Nicole E Bodycombe; Melissa A Marton; Katherine L Sokolnicki; Mark-Anthony Bray; Melissa M Kemp; Ellen Winchester; Bradley Taylor; George B Grant; C Suk-Yee Hon; Jeremy R Duvall; J Anthony Wilson; Joshua A Bittker; Vlado Dančík; Rajiv Narayan; Aravind Subramanian; Wendy Winckler; Todd R Golub; Anne E Carpenter; Alykhan F Shamji; Stuart L Schreiber; Paul A Clemons
Journal: Proc Natl Acad Sci U S A Date: 2014-07-14 Impact factor: 11.205

Review 4. High-Content Screening for Quantitative Cell Biology.

Authors: Mojca Mattiazzi Usaj; Erin B Styles; Adrian J Verster; Helena Friesen; Charles Boone; Brenda J Andrews
Journal: Trends Cell Biol Date: 2016-04-22 Impact factor: 20.808

Review 5. Applications in image-based profiling of perturbations.

Authors: Juan C Caicedo; Shantanu Singh; Anne E Carpenter
Journal: Curr Opin Biotechnol Date: 2016-04-17 Impact factor: 9.740

6. Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery.

Authors: Jaak Simm; Günter Klambauer; Adam Arany; Marvin Steijaert; Jörg Kurt Wegner; Emmanuel Gustin; Vladimir Chupakhin; Yolanda T Chong; Jorge Vialard; Peter Buijnsters; Ingrid Velter; Alexander Vapirev; Shantanu Singh; Anne E Carpenter; Roel Wuyts; Sepp Hochreiter; Yves Moreau; Hugo Ceulemans
Journal: Cell Chem Biol Date: 2018-03-01 Impact factor: 8.116

7. Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation.

Authors: Christopher C Gibson; Weiquan Zhu; Chadwick T Davis; Jay A Bowman-Kirigin; Aubrey C Chan; Jing Ling; Ashley E Walker; Luca Goitre; Simona Delle Monache; Saverio Francesco Retta; Yan-Ting E Shiu; Allie H Grossmann; Kirk R Thomas; Anthony J Donato; Lisa A Lesniewski; Kevin J Whitehead; Dean Y Li
Journal: Circulation Date: 2014-12-08 Impact factor: 29.690

8. High-Throughput Surface Liquid Absorption and Secretion Assays to Identify F508del CFTR Correctors Using Patient Primary Airway Epithelial Cultures.

Authors: Allison Berg; Shawn Hallowell; Mark Tibbetts; Chad Beasley; Tracy Brown-Phillips; Anita Healy; Leslie Pustilnik; Regis Doyonnas; Marko Pregel
Journal: SLAS Discov Date: 2019-05-20 Impact factor: 3.341