Literature DB >> 32189324

Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for CYP2C9 and Nonsteroidal Anti-Inflammatory Drugs.

Katherine N Theken1, Craig R Lee2, Li Gong3, Kelly E Caudle4, Christine M Formea5,6, Andrea Gaedigk7,8, Teri E Klein3, José A G Agúndez9, Tilo Grosser1.   

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used analgesics due to their lack of addictive potential. However, NSAIDs have the potential to cause serious gastrointestinal, renal, and cardiovascular adverse events. CYP2C9 polymorphisms influence metabolism and clearance of several drugs in this class, thereby affecting drug exposure and potentially safety. We summarize evidence from the published literature supporting these associations and provide therapeutic recommendations for NSAIDs based on CYP2C9 genotype (updates at www.cpicpgx.org).
© 2020 The Authors Clinical Pharmacology & Therapeutics © 2020 American Society for Clinical Pharmacology and Therapeutics.

Entities:  

Year:  2020        PMID： 32189324     DOI： 10.1002/cpt.1830

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  43 in total

1.  Sources of Interindividual Variability.

Authors:  Yvonne S Lin; Kenneth E Thummel; Brice D Thompson; Rheem A Totah; Christi W Cho
Journal:  Methods Mol Biol       Date:  2021

2.  Efficacy and Safety of Ibuprofen Plus Paracetamol in a Fixed-Dose Combination for Acute Postoperative Pain in Adults: Meta-Analysis and a Trial Sequential Analysis.

Authors:  Dina Abushanab; Daoud Al-Badriyeh
Journal:  CNS Drugs       Date:  2021-01-11       Impact factor: 5.749

3.  Physiologically based pharmacokinetic (PBPK) modeling of piroxicam with regard to CYP2C9 genetic polymorphism.

Authors:  Chang-Keun Cho; Pureum Kang; Hye-Jung Park; Eunvin Ko; Chou Yen Mu; Yun Jeong Lee; Chang-Ik Choi; Hyung Sik Kim; Choon-Gon Jang; Jung-Woo Bae; Seok-Yong Lee
Journal:  Arch Pharm Res       Date:  2022-05-31       Impact factor: 4.946

Review 4.  Keeping pace with CYP2D6 haplotype discovery: innovative methods to assign function.

Authors:  Karen E Brown; Jack W Staples; Erica L Woodahl
Journal:  Pharmacogenomics       Date:  2022-01-27       Impact factor: 2.533

Review 5.  Pharmacogenetics and Precision Medicine Approaches for the Improvement of COVID-19 Therapies.

Authors:  Mohitosh Biswas; Nares Sawajan; Thanyada Rungrotmongkol; Kamonpan Sanachai; Maliheh Ershadian; Chonlaphat Sukasem
Journal:  Front Pharmacol       Date:  2022-02-18       Impact factor: 5.810

Review 6.  Perioperative Pain Management and Opioid Stewardship: A Practical Guide.

Authors:  Sara J Hyland; Kara K Brockhaus; William R Vincent; Nicole Z Spence; Michelle M Lucki; Michael J Howkins; Robert K Cleary
Journal:  Healthcare (Basel)       Date:  2021-03-16

7.  Pharmacogenomics in cancer supportive care: key issues and future directions.

Authors:  Jai N Patel; Ian Olver; Fred Ashbury
Journal:  Support Care Cancer       Date:  2021-08-01       Impact factor: 3.603

8.  Opportunities for pharmacogenomics-guided supportive care in cancer.

Authors:  Jai N Patel
Journal:  Support Care Cancer       Date:  2021-02       Impact factor: 3.603

9.  Interaction between Omeprazole and Gliclazide in Relation to CYP2C19 Phenotype.

Authors:  Tanja Dujic; Sandra Cvijic; Amar Elezovic; Tamer Bego; Selma Imamovic Kadric; Maja Malenica; Alisa Elezovic; Ewan R Pearson; Aida Kulo
Journal:  J Pers Med       Date:  2021-05-03

10.  CYP2C19 Phenotype and Body Weight-Guided Voriconazole Initial Dose in Infants and Children after Hematopoietic Cell Transplantation.

Authors:  Takuto Takahashi; Maryam A Mohamud; Angela R Smith; Pamala A Jacobson; Mutaz M Jaber; Abeer F Alharbi; James Fisher; Mark N Kirstein
Journal:  Antimicrob Agents Chemother       Date:  2021-08-17       Impact factor: 5.191
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