Carsten Oliver Schmidt1, Klaus-Peter Günther2, Jens Goronzy2, Katinka Albrecht3, Jean-François Chenot4, Johanna Callhoff3, Adrian Richter4, Richard Kasch5, Wolfgang Ahrens6, Heiko Becher7, Klaus Berger8, Hermann Brenner9, Beate Fischer10, Claus-Werner Franzke11, Wolfgang Hoffmann4, Bernd Holleczek12, Lina Jaeschke13, Carsten Jenning4, Karl-Heinz Jöckel14, Rudolf Kaaks9, Thomas Keil15,16,17, Alexander Kluttig18, Gérard Krause19, Oliver Kuß20, Michael Leitzmann10, Wolfgang Lieb21, Jakob Linseisen22,23, Markus Löffler24,25, Claudia Meinke-Franze4, Christa Meisinger22,23, Karin B Michels11, Rafael Mikolajczyk18, Nadia Obi7, Annette Peters23, Tobias Pischon13,26,27,17,28, Tamara Schikowski29, Sabine Schipf4, Christof Specker25, Henry Völzke4, Kerstin Wirkner24,30, Angela Zink3,31, Oliver Sander32. 1. Institut für Community Medicine - SHIP-KEF, Universitätsmedizin Greifswald, Walther-Rathenau-Str. 48, 17475, Greifswald, Deutschland. carsten.schmidt@uni-greifswald.de. 2. Universitätsklinikum Dresden, Dresden, Deutschland. 3. Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Deutschland. 4. Institut für Community Medicine - SHIP-KEF, Universitätsmedizin Greifswald, Walther-Rathenau-Str. 48, 17475, Greifswald, Deutschland. 5. Klinik und Poliklinik für Orthopädie und Chirurgische Orthopädie, Universitätsmedizin Greifswald, Greifswald, Deutschland. 6. Leibniz-Institut für Präventionsforschung und Epidemiologie - BIPS, Bremen, Deutschland. 7. Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland. 8. Westfälische Wilhelms-Universität Münster, Münster, Deutschland. 9. Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Deutschland. 10. Fakultät für Medizin, Universität Regensburg (UR), Regensburg, Deutschland. 11. Institut für Prävention und Tumorepidemiologie, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Freiburg, Deutschland. 12. Ministerium für Soziales Gesundheit Frauen und Familie - Saarland, Saarbrücken, Deutschland. 13. Forschergruppe Molekulare Epidemiologie, Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (MDC), Berlin, Deutschland. 14. Universitätsklinikum Essen, Essen, Deutschland. 15. Institut für Sozialmedizin, Epidemiologie und Gesundheitsökonomie, Charité - Universitätsmedizin Berlin, Berlin, Deutschland. 16. Institut für Klinische Epidemiologie und Biometrie, Universität Würzburg, Würzburg, Deutschland. 17. Landesinstitut für Gesundheit, Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit, Bad Kissingen, Deutschland. 18. Martin-Luther-Universität Halle-Wittenberg, Halle (Saale), Deutschland. 19. Helmholtz-Zentrum für Infektionsforschung (HZI), Braunschweig, Deutschland. 20. Institut für Biometrie und Epidemiologie, Deutsches Diabetes-Zentrum (DDZ), Leibniz-Zentrum für Diabetes-Forschung an der Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Deutschland. 21. Christian-Albrechts-Universität Kiel, Kiel, Deutschland. 22. Lehrstuhl für Epidemiologie, am UNIKA-T, LMU München, Augsburg, Deutschland. 23. SFG Klinische Epidemiologie, Helmholtz Zentrum München, Neuherberg, Deutschland. 24. Institut für Medizinische Informatik, Statistik, und Epidemiologie (IMISE), Universität Leipzig, Leipzig, Deutschland. 25. Klinik für Rheumatologie & Klinische Immunologie, Evang. Kliniken Essen-Mitte, Essen, Deutschland. 26. Partnerstandort Berlin, Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), Berlin, Deutschland. 27. MDC/BIH Biobank, Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (MDC) und Berlin Institute of Health (BIH), Berlin, Deutschland. 28. Charité - Universitätsmedizin Berlin, Berlin, Deutschland. 29. IUF Leibniz-Institut für umweltmedizinische Forschung gGmbH, Düsseldorf, Deutschland. 30. Leipziger Forschungszentrum für Zivilisationserkrankungen (LIFE), Universität Leipzig, Leipzig, Deutschland. 31. Klinik für Rheumatologie und Klinische Immunologie, Charité Universitätsmedizin Berlin, Berlin, Deutschland. 32. Poliklinik und Funktionsbereich für Rheumatologie, Heinrich-Heine-Universität, Düsseldorf, Deutschland.
Abstract
BACKGROUND: Musculoskeletal diseases and symptoms are very common in the general population. They lead to high healthcare costs and pose a significant burden to the national economy. OBJECTIVES: Based on data from the population-based German National Cohort (GNC), frequencies of musculoskeletal symptoms and diseases are reported, including back pain, osteoporosis, osteoarthritis, and arthritis. MATERIALS AND METHODS: Data were collected from March 2014 to March 2017 in adults aged 20-75 years during the first half of the baseline survey of the GNC. The sample comprised 101,779 interviewed subjects, including 9370 subjects who underwent clinical musculoskeletal examinations. The interview included questions about specific musculoskeletal disorders. A clinical examination of the hand provided information about palpable swollen joints and pressure-sensitive joints. Resting pain of the knees and hips was also assessed by a clinical examination. Frequencies were standardized to the German standard population of the year 2011. RESULTS: Having ever been diagnosed with recurrent back pain (22.5%) or osteoarthritis (20.6%) were the most common complaints reported in the interview; osteoporosis (2.9%) and rheumatoid arthritis (1.9%) were stated more seldom. According to the hand examination, 6.0% of all participants experienced pain in at least one finger joint. Resting pain was present in at least one knee among 8.2% and in at least one hip among 5.1% of the participants as assessed during the clinical examination. Women were more likely to report musculoskeletal disorders and symptoms than men. The proportion of adults affected by musculoskeletal diseases increased strongly with age. CONCLUSION: Musculoskeletal disorders and symptoms occur frequently. The burden of complaints and diagnoses is comparable to previous population-based surveys.
BACKGROUND: Musculoskeletal diseases and symptoms are very common in the general population. They lead to high healthcare costs and pose a significant burden to the national economy. OBJECTIVES: Based on data from the population-based German National Cohort (GNC), frequencies of musculoskeletal symptoms and diseases are reported, including back pain, osteoporosis, osteoarthritis, and arthritis. MATERIALS AND METHODS: Data were collected from March 2014 to March 2017 in adults aged 20-75 years during the first half of the baseline survey of the GNC. The sample comprised 101,779 interviewed subjects, including 9370 subjects who underwent clinical musculoskeletal examinations. The interview included questions about specific musculoskeletal disorders. A clinical examination of the hand provided information about palpable swollen joints and pressure-sensitive joints. Resting pain of the knees and hips was also assessed by a clinical examination. Frequencies were standardized to the German standard population of the year 2011. RESULTS: Having ever been diagnosed with recurrent back pain (22.5%) or osteoarthritis (20.6%) were the most common complaints reported in the interview; osteoporosis (2.9%) and rheumatoid arthritis (1.9%) were stated more seldom. According to the hand examination, 6.0% of all participants experienced pain in at least one finger joint. Resting pain was present in at least one knee among 8.2% and in at least one hip among 5.1% of the participants as assessed during the clinical examination. Women were more likely to report musculoskeletal disorders and symptoms than men. The proportion of adults affected by musculoskeletal diseases increased strongly with age. CONCLUSION: Musculoskeletal disorders and symptoms occur frequently. The burden of complaints and diagnoses is comparable to previous population-based surveys.
Entities:
Keywords:
Arthritis; Back pain; General population; Musculoskeletal disorders; Osteoarthritis; Osteoporosis
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