Stephany Jaramillo1, Katharyn L Flickinger2, Melissa Repine3, Maria Pacella-LaBarbara4, Clifton W Callaway5, Allison Koller6, Kevin Cullison7, Jon C Rittenberger8. 1. Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States. Electronic address: Stephany.jaramillo@hotmail.com. 2. Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States. Electronic address: holquistkl@upmc.edu. 3. Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States. Electronic address: mcmimj2@upm.edu. 4. Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States. Electronic address: pacellam@upmc.edu. 5. Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States. Electronic address: callawaycw@upmc.edu. 6. Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States. Electronic address: kollerac@upmc.edu. 7. Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States. Electronic address: cullisonkm@upmc.edu. 8. Department of Emergency Medicine, Guthrie Medical Group, Sayre, PA, United States. Electronic address: Jon.Rittenberger@guthrie.org.
Abstract
BACKGROUND: Long-term assessment of global functional outcomes in cardiac arrest (CA) survivors allows for evaluation of acute care practices and referral to rehabilitation services. Given that many post-CA patients are lost to follow-up (LTFU), we explored whether these patients are systematically different from those who complete follow-up based on demographic, resuscitation and outcome characteristics. METHODS: We conducted a prospective cohort study of 168 English-speaking CA survivors between 9/25/2016 and 5/31/2018. We measured demographic data and global functional outcomes using Modified Rankin Scale (mRS), and Cerebral Performance Category (CPC) in-person at hospital discharge, and via telephone at 3-, 6-months, and 1-year. We compared patients LTFU (e.g., failure to contact or refused to follow-up) with those contacted. Patients who were hospitalized, in a rehabilitation facility, missed by the research team, or dead were considered not eligible for follow-up. RESULTS: Of the 116 patients eligible for follow-up at 3-months, the majority completed follow-up (n = 69; 59.5%) and 47 (40.5%) were LTFU. Conversely, at 6-months and 1-year, fewer subjects were assessed (42% and 47%) compared to those who were LTFU (58% and 53%), respectively. At 3-months, LTFU patients were younger, unmarried, and had longer ICU stay. At 6-months and 1-year, LTFU patients were primarily male, had a non-shockable primary rhythm, and non-cardiac arrest etiologies. CONCLUSIONS: Over one-third of patients are LTFU during the first year after CA, and differences emerged for demographics and characteristics of the event. Future research should account for the informative, non-random distribution of patients LTFU.
BACKGROUND: Long-term assessment of global functional outcomes in cardiac arrest (CA) survivors allows for evaluation of acute care practices and referral to rehabilitation services. Given that many post-CA patients are lost to follow-up (LTFU), we explored whether these patients are systematically different from those who complete follow-up based on demographic, resuscitation and outcome characteristics. METHODS: We conducted a prospective cohort study of 168 English-speaking CA survivors between 9/25/2016 and 5/31/2018. We measured demographic data and global functional outcomes using Modified Rankin Scale (mRS), and Cerebral Performance Category (CPC) in-person at hospital discharge, and via telephone at 3-, 6-months, and 1-year. We compared patients LTFU (e.g., failure to contact or refused to follow-up) with those contacted. Patients who were hospitalized, in a rehabilitation facility, missed by the research team, or dead were considered not eligible for follow-up. RESULTS: Of the 116 patients eligible for follow-up at 3-months, the majority completed follow-up (n = 69; 59.5%) and 47 (40.5%) were LTFU. Conversely, at 6-months and 1-year, fewer subjects were assessed (42% and 47%) compared to those who were LTFU (58% and 53%), respectively. At 3-months, LTFU patients were younger, unmarried, and had longer ICU stay. At 6-months and 1-year, LTFU patients were primarily male, had a non-shockable primary rhythm, and non-cardiac arrest etiologies. CONCLUSIONS: Over one-third of patients are LTFU during the first year after CA, and differences emerged for demographics and characteristics of the event. Future research should account for the informative, non-random distribution of patients LTFU.
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Authors: Katharyn L Flickinger; Stephany Jaramillo; Melissa J Repine; Allison C Koller; Margo Holm; Elizabeth Skidmore; Clif Callaway; Jon C Rittenberger Journal: Resusc Plus Date: 2021-12-06