Literature DB >> 32166376

Clinical characteristics of pediatric hidradenitis suppurativa: a cross-sectional multicenter study of 140 patients.

Peter Theut Riis1,2, Ditte Marie Saunte3,4, Viktoria Sigsgaard3,4, Axel Patrice Villani5,6, Philippe Guillem5, José C Pascual7, Naomi N Kappe8, Annika M J D Vanlaerhoven8, Hessel H van der Zee8, Errol P Prens8, Moetaz El-Domyati9, Hossam Abdel-Wahab9, Nayera Moftah10, Rania Abdelghani10,11, Eugenia Agut-Busquet12,13, Jorge Romaní14, Carol Hlela15, Lerinza van den Worm15, Vincenzo Bettoli16, Giada Calamo16, Mehmet Ali Gürer17, Burcu Beksaç17, Lukasz Matusiak18, Amelia Glowaczewska18, Jacek C Szepietowski18, Lennart Emtestam19, Jan Lapins19, Hassan Riad Kottb20, Mohammad Fatani21, Lisa Weibel22,23, Martin Theiler22,23, Maïa Delage-Toriel24, Thi Thanh Hong Lam24, Aude Nassif24, Pierre-Andre Becherel25, Mateja Dolenc-Voljc26, Nejib Doss27, Dorra Bouazzi3,4, Farida Benhadou28, Veronique Del Marmol28, Gregor B E Jemec3,4.   

Abstract

Hidradenitis suppurativa (HS) rarely affects pediatric patients. The literature on pediatric HS patients is scarce. This is a cross-sectional study based on case note review or interviews and clinical examination of 140 pediatric patients undergoing secondary or tertiary level care. Patients were predominantly female (75.5%, n = 105) with a median age of 16. 39% reported 1st-degree relative with HS. Median BMI percentile was 88, and 11% were smokers (n = 15). Median modified Sartorius score was 8.5. Notable comorbidities found were acne (32.8%, n = 45), hirsutism (19.3%, n = 27), and pilonidal cysts (16.4%, n = 23). Resorcinol (n = 27) and clindamycin (n = 25) were the most frequently used topical treatments. Patients were treated with tetracycline (n = 32), or oral clindamycin and rifampicin in combination (n = 29). Surgical excision was performed in 18 patients, deroofing in five and incision in seven patients. Obesity seemed to be prominent in the pediatric population and correlated to parent BMI, suggesting a potential for preventive measures for the family. Disease management appeared to be similar to that of adult HS, bearing in mind that the younger the patient, the milder the disease in majority of cases.

Entities:  

Keywords:  Acne inversa; Children; Hidradenitis suppurativa; Pediatric

Mesh:

Substances:

Year:  2020        PMID: 32166376     DOI: 10.1007/s00403-020-02053-6

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN: 0340-3696            Impact factor:   3.017


  52 in total

1.  Development and evaluation of a Global Acne Severity Scale (GEA Scale) suitable for France and Europe.

Authors:  B Dréno; F Poli; H Pawin; C Beylot; M Faure; M Chivot; N Auffret; D Moyse; F Ballanger; J Revuz
Journal:  J Eur Acad Dermatol Venereol       Date:  2011-01       Impact factor: 6.166

Review 2.  The Handicap of Hidradenitis Suppurativa.

Authors:  Inge Elizabeth Deckers; Alexa Boer Kimball
Journal:  Dermatol Clin       Date:  2015-09-14       Impact factor: 3.478

3.  Hidradenitis suppurativa-acne inversa: a relevant dermatosis in paediatric patients.

Authors:  V Bettoli; M Ricci; S Zauli; A Virgili
Journal:  Br J Dermatol       Date:  2015-08-31       Impact factor: 9.302

4.  Correlation of early-onset hidradenitis suppurativa with stronger genetic susceptibility and more widespread involvement.

Authors:  Inge E Deckers; Hessel H van der Zee; Jurr Boer; Errol P Prens
Journal:  J Am Acad Dermatol       Date:  2015-01-10       Impact factor: 11.527

5.  Hidradenitis suppurativa in children: The Henry Ford experience.

Authors:  Taylor L Braunberger; Cynthia L Nicholson; Lauren Gold; Amanda F Nahhas; Gordon Jacobsen; Angela Parks-Miller; Iltefat H Hamzavi
Journal:  Pediatr Dermatol       Date:  2018-03-25       Impact factor: 1.588

6.  Links between the organization of the family home environment and child obesity: a systematic review.

Authors:  C R Bates; J Buscemi; L M Nicholson; M Cory; A Jagpal; A M Bohnert
Journal:  Obes Rev       Date:  2018-03-08       Impact factor: 9.213

Review 7.  Idiopathic hirsutism.

Authors:  R Azziz; E Carmina; M E Sawaya
Journal:  Endocr Rev       Date:  2000-08       Impact factor: 19.871

8.  Psychosocial impact of hidradenitis suppurativa: a qualitative study.

Authors:  Solveig Esmann; Gregor B E Jemec
Journal:  Acta Derm Venereol       Date:  2011-05       Impact factor: 4.437

9.  Clinical characteristics of a series of 302 French patients with hidradenitis suppurativa, with an analysis of factors associated with disease severity.

Authors:  Florence Canoui-Poitrine; Jean E Revuz; Pierre Wolkenstein; Cédric Viallette; Germaine Gabison; Florence Pouget; Florence Poli; Ousmane Faye; Sylvie Bastuji-Garin
Journal:  J Am Acad Dermatol       Date:  2009-04-29       Impact factor: 11.527

Review 10.  Pilonidal sinus disease.

Authors:  V de Parades; D Bouchard; M Janier; A Berger
Journal:  J Visc Surg       Date:  2013-08-01       Impact factor: 2.043

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  2 in total

1.  Physical and psychosocial comorbidities of pediatric hidradenitis suppurativa: A retrospective analysis.

Authors:  Justine R Seivright; Erin Collier; Tristan Grogan; Marcia Hogeling; Vivian Y Shi; Jennifer L Hsiao
Journal:  Pediatr Dermatol       Date:  2021-08-31       Impact factor: 1.997

2.  Biologic Use in Pediatric Patients With Hidradenitis Suppurativa: A Systematic Review.

Authors:  Muskaan Sachdeva; Patrick Kim; Asfandyar Mufti; Khalad Maliyar; Cathryn Sibbald; Afsaneh Alavi
Journal:  J Cutan Med Surg       Date:  2021-09-29       Impact factor: 2.092

  2 in total

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