Literature DB >> 32158053

The Benefits of Omega-3 Fats for Stabilizing and Remodeling Atherosclerosis.

James J DiNicolantonio1, James H O'Keefe1.   

Abstract

The majority of acute coronary syndromes are caused by the rupture of plaques rendered vulnerable by oxidized lipids, inflammation, and a thin fibrous cap with reduced collagen and smooth muscle cell content.2 Thus, stabilizing and reversing vulnerable atherosclerotic plaques can help to prevent cardiovascular events. In this regard, long-chain omega-3 fatty acids have a plethora of data for stabilizing vulnerable atherosclerotic plaques as well as reversing atherosclerosis. This review paper will summarize the observational data as well as animal and human studies supporting such a role and further discuss the current controversies around omega-3 supplementation. Copyright 2020 by the Missouri State Medical Association.

Entities:  

Year:  2020        PMID： 32158053      PMCID： PMC7023944     

Source DB:  PubMed          Journal:  Mo Med        ISSN： 0026-6620


  34 in total

1.  Genetic strategies to elucidate the roles of matrix metalloproteinases in atherosclerotic plaque growth and stability.

Authors:  Andrew C Newby; Jason L Johnson
Journal:  Circ Res       Date:  2005-11-11       Impact factor: 17.367

2.  The big ones that got away: omega-3 meta-analysis flawed by excluding the biggest fish oil trials.

Authors:  James J DiNicolantonio; James H O'Keefe; Carl J Lavie
Journal:  Arch Intern Med       Date:  2012-10-08

3.  Atherosclerosis and omega-3 fatty acids in the populations of a fishing village and a farming village in Japan.

Authors:  T Yamada; J P Strong; T Ishii; T Ueno; M Koyama; H Wagayama; A Shimizu; T Sakai; G T Malcom; M A Guzman
Journal:  Atherosclerosis       Date:  2000-12       Impact factor: 5.162

4.  Impact of omega-3 polyunsaturated fatty acids on coronary plaque instability: an integrated backscatter intravascular ultrasound study.

Authors:  Tetsuya Amano; Tatsuaki Matsubara; Tadayuki Uetani; Masataka Kato; Bunichi Kato; Tomohiro Yoshida; Ken Harada; Soichiro Kumagai; Ayako Kunimura; Yusaku Shinbo; Katsuhide Kitagawa; Hideki Ishii; Toyoaki Murohara
Journal:  Atherosclerosis       Date:  2011-06-01       Impact factor: 5.162

5.  Endogenously decreasing tissue n-6/n-3 fatty acid ratio reduces atherosclerotic lesions in apolipoprotein E-deficient mice by inhibiting systemic and vascular inflammation.

Authors:  Jian-Bo Wan; Li-Li Huang; Rong Rong; Rui Tan; Jingdong Wang; Jing X Kang
Journal:  Arterioscler Thromb Vasc Biol       Date:  2010-08-12       Impact factor: 8.311

6.  Eicosapentaenoic acid reduces the progression of carotid intima-media thickness in patients with type 2 diabetes.

Authors:  Tomoya Mita; Hirotaka Watada; Takeshi Ogihara; Takashi Nomiyama; Osamu Ogawa; Junichiro Kinoshita; Tomoaki Shimizu; Takahisa Hirose; Yasushi Tanaka; Ryuzo Kawamori
Journal:  Atherosclerosis       Date:  2006-04-17       Impact factor: 5.162

7.  Orally administered eicosapentaenoic acid reduces and stabilizes atherosclerotic lesions in ApoE-deficient mice.

Authors:  Miwa Matsumoto; Masataka Sata; Daiju Fukuda; Kimie Tanaka; Masaaki Soma; Yasunobu Hirata; Ryozo Nagai
Journal:  Atherosclerosis       Date:  2007-09-04       Impact factor: 5.162

8.  Dietary omega-3, omega-6, and omega-9 unsaturated fatty acids and growth factor and cytokine gene expression in unstimulated and stimulated monocytes. A randomized volunteer study.

Authors:  K H Baumann; F Hessel; I Larass; T Müller; P Angerer; R Kiefl; C von Schacky
Journal:  Arterioscler Thromb Vasc Biol       Date:  1999-01       Impact factor: 8.311

9.  Plasma phospholipid EPA and DHA in relation to atherosclerosis in 61-year-old men.

Authors:  Helen M Lindqvist; Ann-Sofie Sandberg; Björn Fagerberg; Johannes Hulthe
Journal:  Atherosclerosis       Date:  2008-12-30       Impact factor: 5.162

10.  Dietary eicosapentaenoic acid and docosahexaenoic acid from fish oil. Their incorporation into advanced human atherosclerotic plaques.

Authors:  J H Rapp; W E Connor; D S Lin; J M Porter
Journal:  Arterioscler Thromb       Date:  1991 Jul-Aug
View more
  2 in total

1.  Comparative study of the ameliorative effects of omega-3 versus selenium on etoposide-induced changes in Sertoli cells and ectoplasmic specialization of adult rat testes: immunohistochemical and electron microscopic study.

Authors:  Yomna F Hassan; Hanaa A Khalaf; Nesreen M Omar; Zeinab A Sakkara; Amal M Moustafa
Journal:  J Mol Histol       Date:  2022-02-03       Impact factor: 2.611

Review 2.  Immune and Inflammation in Acute Coronary Syndrome: Molecular Mechanisms and Therapeutic Implications.

Authors:  Haiming Wang; Zifan Liu; Junjie Shao; Lejian Lin; Min Jiang; Lin Wang; Xuechun Lu; Haomin Zhang; Yundai Chen; Ran Zhang
Journal:  J Immunol Res       Date:  2020-08-18       Impact factor: 4.818
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.