| Literature DB >> 32151218 |
Daniel M Rolston1,2, Timmy Li1, Casey Owens2, Ghania Haddad2, Timothy J Palmieri1,2, Veronika Blinder1, Jennifer L Wolff1, Michael Cassara1,2, Qiuping Zhou1,2, Lance B Becker1,2.
Abstract
Background Outcomes in cardiac arrest remain suboptimal. Mechanical cardiopulmonary resuscitation (CPR) has not demonstrated clear clinical benefit; however, video review provides the capability to monitor CPR quality and provide constructive feedback to individuals and teams to improve their performance. The aim of our study was to evaluate cardiac arrest outcomes before and after initiation of a mechanical, team-focused, video-reviewed CPR intervention. Methods and Results In 2018, our emergency department began using mechanical CPR; a new team-focused strategy with nurse-led Advanced Cardiovascular Life Support; and biweekly, multidisciplinary video review of cardiac arrests. A revised approach to resuscitation was generated from a performance improvement session, and in situ simulation was used to disseminate our approach. The primary outcome of this study was the return of spontaneous circulation rate before and after our mechanical, team-focused, video-reviewed CPR intervention. Secondary outcomes included survival to admission and discharge. Multivariable logistic regression modeling was used. The pre- and postintervention groups were similar at baseline. A total of 248 patients were included in our study (97 before and 151 after mechanical, team-focused, video-reviewed CPR). Return of spontaneous circulation was higher in the intervention group (41% versus 26%; P=0.014). There were nonsignificant increases in survival to admission (26% versus 20%; P=0.257) and survival to discharge (7% versus 3%; P=0.163). After controlling for covariates, the odds of return of spontaneous circulation remained higher after the intervention (odds ratio, 2.11; 95% CI, 1.14-3.89). Conclusions Implementation of our mechanical, team-focused, video-reviewed CPR intervention for cardiac arrest patients in our emergency department improved return of spontaneous circulation rates. Survival to hospital admission and discharge did not improve.Entities:
Keywords: cardiac arrest; cardiopulmonary resuscitation; emergency department; high performance; mechanical chest compressions; quality improvement; team‐based care
Mesh:
Year: 2020 PMID: 32151218 PMCID: PMC7335530 DOI: 10.1161/JAHA.119.014420
Source DB: PubMed Journal: J Am Heart Assoc ISSN: 2047-9980 Impact factor: 5.501
Figure 1Study sample flowchart.
Patients who had prehospital
Figure 2Team‐focused mechanical cardiac arrest diagram.
Figure 3Cardiac arrest video review scorecard. ACLS indicates Advanced Cardiovascular Life Support; AED, automated external defibrillator; BVM, bag‐valve‐mask; CPR, cardiopulmonary resuscitation; ED, emergency department; EMS, emergency medical services; ET, endotracheal; ETCO 2, end‐tidal carbon dioxide; IO, intraosseous; IV, intravenous; LUCAS, Lund University Cardiopulmonary Assist System; PA, physician assistant; and PEA, pulseless electrical activity.
Characteristics of the Study Sample Stratified by Time Period
| Variable | Total Sample (n=248) | Before (n=97) | After (n=151) |
|
|---|---|---|---|---|
| Age, y | 0.286 | |||
| Median (IQR) | 80 (66–89) | 83 (67–90) | 79 (65–88) | |
| Sex | 0.868 | |||
| Male, n (%) | 139 (56.1) | 55 (56.7) | 84 (55.6) | |
| Female, n (%) | 109 (44.0) | 42 (43.3) | 67 (44.4) | |
| Race | 0.192 | |||
| White, n (%) | 159 (64.1) | 67 (69.1) | 92 (60.9) | |
| Nonwhite, n (%) | 89 (35.9) | 30 (30.9) | 59 (39.1) | |
| Ethnicity | 0.942 | |||
| Hispanic or Latino, n (%) | 15 (6.1) | 6 (6.2) | 9 (6.0) | |
| Not Hispanic or Latino, n (%) | 233 (94.0) | 91 (93.8) | 142 (94.0) | |
| Cardiac arrest location | 0.674 | |||
| Out‐of‐hospital, n (%) | 183 (73.8) | 73 (75.3) | 110 (72.9) | |
| In‐hospital, n (%) | 65 (26.2) | 24 (24.7) | 41 (27.2) | |
| First cardiac rhythm | 0.764 | |||
| Asystole, n (%) | 110 (44.4) | 45 (46.4) | 65 (43.1) | |
| Pulseless electrical activity, n (%) | 72 (29.0) | 25 (25.8) | 47 (31.1) | |
| Ventricular fibrillation/tachycardia, n (%) | 37 (14.9) | 14 (14.4) | 23 (15.2) | |
| Unknown/not documented, n (%) | 29 (11.7) | 13 (13.4) | 16 (10.6) | |
| Cardiac arrest witnessed by | 0.402 | |||
| Bystander, n (%) | 64 (25.8) | 30 (30.9) | 34 (22.5) | |
| EMS, n (%) | 25 (10.1) | 11 (11.3) | 14 (9.3) | |
| ED staff, n (%) | 65 (26.2) | 24 (24.7) | 41 (27.2) | |
| Unwitnessed, n (%) | 76 (30.7) | 24 (24.7) | 52 (34.4) | |
| Unknown, n (%) | 18 (7.3) | 8 (8.3) | 10 (6.6) | |
| CPR initiated by | 0.871 | |||
| Bystander, n (%) | 43 (17.3) | 16 (16.5) | 27 (17.9) | |
| EMS/police/fire, n (%) | 127 (51.2) | 50 (51.6) | 77 (51.0) | |
| ED staff, n (%) | 66 (26.6) | 25 (25.8) | 41 (27.2) | |
| Unknown, n (%) | 12 (4.8) | 6 (6.2) | 6 (4.0) | |
| First defibrillation by | 0.032 | |||
| Bystander or first responder, n (%) | 16 (6.5) | 10 (10.3) | 6 (4.0) | |
| EMS, n (%) | 39 (15.7) | 16 (16.5) | 23 (15.2) | |
| ED staff, n (%) | 18 (7.3) | 4 (4.1) | 14 (9.3) | |
| Not defibrillated, n (%) | 109 (44.0) | 35 (36.1 | 74 (49.0) | |
| Unknown/not documented, n (%) | 66 (26.6) | 32 (33.0 | 34 (22.5) | |
| Independent living | 0.003 | |||
| Yes, n (%) | 107 (43.2) | 36 (37.1) | 71 (47.0) | |
| No, n (%) | 85 (34.3) | 28 (28.9) | 57 (37.8) | |
| Unknown, n (%) | 56 (22.6) | 33 (34.0) | 23 (15.2) | |
| EMS dispatch to ED arrival time | 0.640 | |||
| Median min (IQR) | 41 (33–52) | 43 (31–53) | 41 (34–52) |
P‐values derived from Wilcoxon rank‐sum test for age and chi‐square or Fisher's exact tests where appropriate for all other categorical variables. ED indicates emergency department; EMS, emergency medical services; IQR, interquartile range; and MTV‐CPR, mechanical, team‐focused, video‐reviewed cardiopulmonary resuscitation.
Outcomes of Cardiac Arrest Resuscitation by Time Period
| Outcomes | Before MTV‐CPR (n=97) | After MTV‐CPR (n=151) |
|
|---|---|---|---|
| ROSC achieved, n (%) | 25 (25.8) | 62 (41.1) | 0.014 |
| OHCA, n (%) | 16 (21.9) | 38 (34.6) | 0.016 |
| IHCA, n (%) | 9 (37.5) | 24 (58.5) | |
| Survival to admission, n (%) | 19 (19.6) | 39 (25.8) | 0.257 |
| Survival to discharge, n (%) | 3 (3.1) | 11 (7.3) | 0.163 |
IHCA indicates in‐hospital cardiac arrest; MTV‐CPR, mechanical, team‐focused, video‐reviewed cardiopulmonary resuscitation; OHCA, out‐of‐hospital cardiac arrest; and ROSC, return of spontaneous circulation.
P value derived from chi‐square test.
P value derived from Cochran‐Mantel‐Haenszel test for general association.
Multivariable Logistic Regression Models on Outcomes Associated With MTV‐CPR Intervention
| Outcomes | Adjusted Odds Ratio | 95% CI |
|---|---|---|
| ROSC achieved | 2.11 | (1.14–3.89) |
| Survival to admission | 1.29 | (0.65–2.54) |
| Survival to discharge | 2.58 | (0.66–10.10) |
MTV‐CPR indicates mechanical, team‐focused, video‐reviewed cardiopulmonary resuscitation; ROSC, return of spontaneous circulation.
Model adjusted for age, sex, initial cardiac rhythm, and witnessed status. Hosmer–Lemeshow goodness‐of‐fit test P value: 0.703.
Model adjusted for age, sex, initial cardiac rhythm, and witnessed status. Hosmer–Lemeshow goodness‐of‐fit test P value: 0.516.
Model adjusted for age, sex, race, and location of cardiac arrest. Hosmer–Lemeshow goodness‐of‐fit test P‐value: 0.857.