Nancy H Liu1,2, Chaorong Wu3, Eliseo J Pérez-Stable4, Ricardo F Muñoz5,2. 1. Department of Psychology, University of California, Berkeley, Berkeley, CA. 2. Department of Psychiatry, Zuckerberg San Francisco General Hospital, University of California, San Francisco, San Francisco, CA. 3. Institute for Clinical and Translational Science, University of Iowa Hospitals and Clinics, Iowa City, IA. 4. Division of Intramural Research, National Heart, Lung, and Blood Institute, and National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD. 5. Department of Psychology, Palo Alto University, Palo Alto, CA.
Abstract
INTRODUCTION: We use multilevel modeling to parse out the effects of time-varying smoking abstinence and baseline depression (history and severity) on depression severity over 1 year. AIMS AND METHODS: Participants were 1000 smokers recruited worldwide for an online randomized controlled tobacco cessation trial. We examined whether changes in depression severity over time were associated with self-reported 7-day point prevalence smoking status assessed at 1-, 3-, 6-, and 12-month follow-up (FU) using baseline major depressive episode (MDE) history and baseline depression severity as time-invariant covariates. We present depression severity means and smoking abstinence at each FU. RESULTS: Regardless of concurrent abstinence status, baseline MDE history was significantly related to depression severity over time: those reporting a past MDE had worse depressive symptoms over time compared with those reporting no MDE history. Baseline depression severity interacted significantly with time-varying abstinence status: for every 1-unit increase in baseline scores on the Center for Epidemiological Studies-Depression Scale (CES-D), individuals who were smoking at FU reported CES-D scores that were 0.17 points higher than those who were abstinent. In this context, nicotine dependence, gender, age, or marital status did not affect depression severity. CONCLUSIONS: In the context of cessation, having an MDE history plays a significant role in the trajectory of depression severity over the course of 1 year, regardless of abstinence status. Abstinence is related to lower depressive symptoms at each FU, and this effect was stronger at higher levels of baseline depression severity. IMPLICATIONS: This study indicates that depressive symptoms are not exacerbated among individuals who are quitting smoking at 1-, 3-, 6-, and 12-month FUs. Depression severity is worse with a baseline history of MDE. Further, those with high baseline depression severity who continue smoking have worse depressive symptoms throughout a 1-year period compared with their abstinent counterparts. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco 2020.
RCT Entities:
INTRODUCTION: We use multilevel modeling to parse out the effects of time-varying smoking abstinence and baseline depression (history and severity) on depression severity over 1 year. AIMS AND METHODS: Participants were 1000 smokers recruited worldwide for an online randomized controlled tobacco cessation trial. We examined whether changes in depression severity over time were associated with self-reported 7-day point prevalence smoking status assessed at 1-, 3-, 6-, and 12-month follow-up (FU) using baseline major depressive episode (MDE) history and baseline depression severity as time-invariant covariates. We present depression severity means and smoking abstinence at each FU. RESULTS: Regardless of concurrent abstinence status, baseline MDE history was significantly related to depression severity over time: those reporting a past MDE had worse depressive symptoms over time compared with those reporting no MDE history. Baseline depression severity interacted significantly with time-varying abstinence status: for every 1-unit increase in baseline scores on the Center for Epidemiological Studies-Depression Scale (CES-D), individuals who were smoking at FU reported CES-D scores that were 0.17 points higher than those who were abstinent. In this context, nicotine dependence, gender, age, or marital status did not affect depression severity. CONCLUSIONS: In the context of cessation, having an MDE history plays a significant role in the trajectory of depression severity over the course of 1 year, regardless of abstinence status. Abstinence is related to lower depressive symptoms at each FU, and this effect was stronger at higher levels of baseline depression severity. IMPLICATIONS: This study indicates that depressive symptoms are not exacerbated among individuals who are quitting smoking at 1-, 3-, 6-, and 12-month FUs. Depression severity is worse with a baseline history of MDE. Further, those with high baseline depression severity who continue smoking have worse depressive symptoms throughout a 1-year period compared with their abstinent counterparts. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco 2020.
Authors: Ricardo F Muñoz; Alinne Z Barrera; Kevin Delucchi; Carlos Penilla; Leandro D Torres; Eliseo J Pérez-Stable Journal: Nicotine Tob Res Date: 2009-07-29 Impact factor: 4.244
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Authors: Christopher W Kahler; Richard A Brown; Susan E Ramsey; Raymond Niaura; David B Abrams; Michael G Goldstein; Timothy I Mueller; Ivan W Miller Journal: J Abnorm Psychol Date: 2002-11
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Authors: Sotiria V Anastasopoulou; Konstantinos S Bonotis; Chrissi Hatzoglou; Konstantinos C Dafopoulos; Konstantinos I Gourgoulianis Journal: Womens Health Rep (New Rochelle) Date: 2022-02-10