Literature DB >> 32147780

Management of the Failed OCD.

Crystal A Perkins1, S Clifton Willimon2.   

Abstract

PURPOSE OF THE REVIEW: Osteochondritis dissecans (OCD) is a pathologic condition of subchondral bone most frequently occurring in the medial femoral condyle of the knee in children and adolescents. Salvage techniques are necessary when either nonoperative or typical operative treatments fail, or the OCD presents in an unsalvageable state. The purpose of this review is to describe the evaluation and management of failed OCDs. RECENT
FINDINGS: Thorough preoperative planning is essential to the treatment of failed OCDs. Radiographs and advanced imaging such as MRI and CT allow for a detailed assessment of subchondral bone and cartilage. Long-leg alignment radiographs are critical to assess for malalignment which may increase the contact forces on the affected condyle. Malalignment can be corrected with hemiepiphysiodesis or an osteotomy depending on the skeletal maturity of the patient. Osteochondral allografts and autologous chondrocyte implantation treat the defect in both bone and cartilage or solely cartilage and have good short to moderate term outcomes, particularly as compared to the inferior outcomes of microfracture of larger OCDs. Osteochondritis dissecans of the knee that fails to heal with initial operative measures can result in a large defect of bone and cartilage in the knee of adolescents. Treatment of the bone and cartilage defect can be accomplished with either osteochondral allograft transplantation or matrix-assisted autologous chondrocyte implantation can be performed with good outcomes. Assessment and correction of lower extremity malalignment is a critical component of treatment. Durable long-term solutions are necessary for the treatment of these difficult lesions.

Entities:  

Keywords:  Autologous chondrocyte implantation; Cartilage; Osteochondral allograft; Osteochondritis dissecans

Year:  2020        PMID: 32147780      PMCID: PMC7174455          DOI: 10.1007/s12178-020-09611-5

Source DB:  PubMed          Journal:  Curr Rev Musculoskelet Med        ISSN: 1935-9748


  48 in total

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Authors:  D M Eastwood; A P Sanghrajka
Journal:  J Bone Joint Surg Br       Date:  2011-01

2.  The shorthand bone age assessment: a simpler alternative to current methods.

Authors:  Benton E Heyworth; Daniel A Osei; Peter D Fabricant; Robert Schneider; Shevaun M Doyle; Daniel W Green; Roger F Widmann; Stephen Lyman; Stephen W Burke; David M Scher
Journal:  J Pediatr Orthop       Date:  2013 Jul-Aug       Impact factor: 2.324

3.  American Academy of Orthopaedic Surgeons clinical practice guideline on: the diagnosis and treatment of osteochondritis dissecans.

Authors:  Henry G Chambers; Kevin G Shea; Allen F Anderson; Tommy J Jojo Brunelle; James L Carey; Theodore J Ganley; Mark Paterno; Jennifer M Weiss; James O Sanders; William C Watters; Michael J Goldberg; Michael W Keith; Charles M Turkelson; Janet L Wies; Laura Raymond; Kevin M Boyer; Kristin Hitchcock; Patrick Sluka; Catherine Boone; Nilay Patel
Journal:  J Bone Joint Surg Am       Date:  2012-07-18       Impact factor: 5.284

4.  Lower patient-reported function at 2 years is associated with elevated knee cartilage T1rho and T2 relaxation times at 5 years in young athletes after ACL reconstruction.

Authors:  Matthew P Ithurburn; Andrew M Zbojniewicz; Staci Thomas; Kevin D Evans; Michael L Pennell; Robert A Magnussen; Mark V Paterno; Laura C Schmitt
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2018-11-16       Impact factor: 4.342

5.  Matrix-Applied Characterized Autologous Cultured Chondrocytes Versus Microfracture: Five-Year Follow-up of a Prospective Randomized Trial.

Authors:  Mats Brittberg; David Recker; John Ilgenfritz; Daniel B F Saris
Journal:  Am J Sports Med       Date:  2018-03-22       Impact factor: 6.202

6.  Percutaneous epiphysiodesis using transphyseal screws (PETS): prospective case study and review.

Authors:  Fred Nouth; Leonard A Kuo
Journal:  J Pediatr Orthop       Date:  2004 Nov-Dec       Impact factor: 2.324

7.  Autologous chondrocyte implantation versus matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: a prospective, randomised study.

Authors:  W Bartlett; J A Skinner; C R Gooding; R W J Carrington; A M Flanagan; T W R Briggs; G Bentley
Journal:  J Bone Joint Surg Br       Date:  2005-05

8.  Analysis of cartilage tissue on a cellular level in fresh osteochondral allograft retrievals.

Authors:  Seth K Williams; David Amiel; Scott T Ball; R Todd Allen; William L Tontz; Bryan C Emmerson; Neil M Badlani; Shawn C Emery; Parviz Haghighi; William D Bugbee
Journal:  Am J Sports Med       Date:  2007-08-27       Impact factor: 6.202

9.  Matrix-induced autologous chondrocyte implantation versus microfracture in the treatment of cartilage defects of the knee: a 2-year randomised study.

Authors:  Erhan Basad; Bernd Ishaque; Georg Bachmann; Henning Stürz; Jürgen Steinmeyer
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-04       Impact factor: 4.342

10.  T1rho mapping of entire femoral cartilage using depth- and angle-dependent analysis.

Authors:  Taiki Nozaki; Yasuhito Kaneko; Hon J Yu; Kayleigh Kaneshiro; Ran Schwarzkopf; Takeshi Hara; Hiroshi Yoshioka
Journal:  Eur Radiol       Date:  2015-09-22       Impact factor: 5.315

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  2 in total

Review 1.  Osteochondral tissue engineering: Perspectives for clinical application and preclinical development.

Authors:  Chengchong Ai; Yee Han Dave Lee; Xuan Hao Tan; Si Heng Sharon Tan; James Hoi Po Hui; James Cho-Hong Goh
Journal:  J Orthop Translat       Date:  2021-10-11       Impact factor: 5.191

2.  Sandwich Technique for Large Osteochondral Lesions of the Knee.

Authors:  C Holwein; P M Jungmann; J Suchowierski; A S Gersing; K Wörtler; P U Brucker; P Angele; A B Imhoff; S Vogt
Journal:  Cartilage       Date:  2022 Jul-Sep       Impact factor: 3.117

  2 in total

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