Literature DB >> 32144601

Poor Knowledge of Personal and Familial Colorectal Cancer Risk and Screening Recommendations Associated with Advanced Colorectal Polyps.

Swati G Patel1,2, Dennis J Ahnen3, Amitha Gumidyala3,4, Jeannine Espinoza3, Andrew Nicklawsky3, Junxiao Hu3, Derek Smith3, Jan Lowery3, Gregory Austin3, Myles Cockburn3,5.   

Abstract

BACKGROUND AND AIMS: Advanced colorectal polyps (adenoma or sessile serrated polyp ≥ 1 cm, adenoma with villous features, adenoma with high-grade dysplasia, or any sessile serrated polyps with dysplasia) are associated with an increased risk of future advanced colorectal neoplasia and confer an increased risk of advanced neoplasia to first-degree family members. Professional societies therefore recommend more intensive surveillance of these polyps and earlier screening for first-degree relatives. The aim of this study was to assess knowledge of personal and familial risk and recommendations among patients with advanced colorectal polyps and identify predictors of knowledge.
METHODS: An online survey was designed to assess the domains of knowledge and risk perception regarding personal and familial colorectal cancer risk and screening recommendations. After expert review and pilot testing, the 37-item survey was electronically sent to all patients diagnosed with an advanced colon or rectal polyp under the age of 60. Patient report of polyp findings was compared to documented findings in the medical record. Univariable and multivariable regressions were performed to evaluate predictors of knowledge.
RESULTS: One hundred thirty-seven out of 344 (39.8%) eligible patients responded to the survey. 28.5% of participants reported that the polyp they had removed was precancerous. 54.8% of participants reported that they have a higher risk of CRC, and 65.2% reported that they should be undergoing colonoscopy surveillance in 3 years or less. 40.1% reported that their first-degree family members are at increased CRC risk, and 38.0% reported that first-degree family members should get earlier screening. Participants reported their endoscopists as their top source of information about risk and recommendations, though only 7.3% of endoscopists made recommendations for family members. Female gender and higher income were predictors of accurate knowledge, as endoscopist was the main source of knowledge.
CONCLUSIONS: Patients with advanced colorectal polyps have poor knowledge of personal and familial CRC risk and recommendations. Endoscopists who remove advanced polyps are in an ideal position to educate their patients about their personal risk and the risk and recommendations for first-degree family members.

Entities:  

Keywords:  Adenoma; Colorectal cancer; Family history; Screening; Serrated polyp; Surveillance

Year:  2020        PMID: 32144601      PMCID: PMC7513555          DOI: 10.1007/s10620-020-06167-9

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  15 in total

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Review 2.  Individual-level factors in colorectal cancer screening: a review of the literature on the relation of individual-level health behavior constructs and screening behavior.

Authors:  Marc T Kiviniemi; Alyssa Bennett; Marie Zaiter; James R Marshall
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4.  A randomized trial to increase colonoscopy screening in members of high-risk families in the colorectal cancer family registry and cancer genetics network.

Authors:  Jan T Lowery; Nora Horick; Anita Y Kinney; Dianne M Finkelstein; Kathleen Garrett; Robert W Haile; Noralane M Lindor; Polly A Newcomb; Robert S Sandler; Carol Burke; Deirdre A Hill; Dennis J Ahnen
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5.  Measuring perceptions of breast cancer risk.

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6.  Colorectal Cancer Screening: Recommendations for Physicians and Patients From the U.S. Multi-Society Task Force on Colorectal Cancer.

Authors:  Douglas K Rex; C Richard Boland; Jason A Dominitz; Francis M Giardiello; David A Johnson; Tonya Kaltenbach; Theodore R Levin; David Lieberman; Douglas J Robertson
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7.  Patient Beliefs About Colon Cancer Screening.

Authors:  John W Ely; Barcey T Levy; Jeanette Daly; Yinghui Xu
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8.  Deficiencies in knowledge and familial risk communication among colorectal adenoma patients.

Authors:  Paul C Schroy; Subodh K Lal; Sheila Wilson; Timothy Heeren; Francis A Farraye
Journal:  J Clin Gastroenterol       Date:  2005-04       Impact factor: 3.062

9.  Colonoscopic screening of first-degree relatives of patients with large adenomas: increased risk of colorectal tumors.

Authors:  Vanessa Cottet; Alexandre Pariente; Bernard Nalet; Jacques Lafon; Chantal Milan; Sylviane Olschwang; Catherine Bonaiti-Pellié; Jean Faivre; Claire Bonithon-Kopp
Journal:  Gastroenterology       Date:  2007-07-25       Impact factor: 22.682

Review 10.  Relative and absolute risk of colorectal cancer for individuals with a family history: a meta-analysis.

Authors:  Adam S Butterworth; Julian P T Higgins; Paul Pharoah
Journal:  Eur J Cancer       Date:  2005-12-09       Impact factor: 9.162

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  2 in total

Review 1.  Increased Risk of Colorectal Cancer Tied to Advanced Colorectal Polyps: An Untapped Opportunity to Screen First-Degree Relatives and Decrease Cancer Burden.

Authors:  Jennifer M Kolb; Christine L Molmenti; Swati G Patel; David A Lieberman; Dennis J Ahnen
Journal:  Am J Gastroenterol       Date:  2020-07       Impact factor: 12.045

2.  Early-Age Onset Colorectal Neoplasia in Average-Risk Individuals Undergoing Screening Colonoscopy: A Systematic Review and Meta-Analysis.

Authors:  Jennifer M Kolb; Junxiao Hu; Kristen DeSanto; Dexiang Gao; Siddharth Singh; Thomas Imperiale; David A Lieberman; C Richard Boland; Swati G Patel
Journal:  Gastroenterology       Date:  2021-06-10       Impact factor: 33.883

  2 in total

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