Literature DB >> 321243

Demonstration of a tryptaminergic mechanism in the rat beta-cell.

O Pulido, A de Bold, M de Bold, S Bencome.   

Abstract

Yellow 5-HT fluorescence has been histochemically demonstrated in rat pancreatic islet cells in animals injected with L-5-HTP with or without pretreatment with the monoaminoxidase inhibitor nialamide. This fluorescence was not observed after inhibition of the aromatic amino acid decarobxylase. The results strongly suggest the presence of a tryptaminergic mechanism in the rat islet cells.

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Year:  1977        PMID： 321243     DOI： 10.1007/bf02124105

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  The neural crest and the origin of the insulin-producing and other gastrointestinal hormone-producing cells.

Authors:  R L Pictet; L B Rall; P Phelps; W J Rutter
Journal:  Science       Date:  1976-01-16       Impact factor: 47.728

Review 2.  Neuroendocrine embryology and the APUD concept.

Authors:  A G Pearse; T T Takor
Journal:  Clin Endocrinol (Oxf)       Date:  1976       Impact factor: 3.478

3.  Amino acid conversion into 5-hydroxytryptamine in pancreatic beta-cells.

Authors:  E Gylfe; B Hellman; J Sehlin; I B Taljedal
Journal:  Endocrinology       Date:  1973-10       Impact factor: 4.736

4.  Catechol- and indolamines in some endocrine cell systems. An autoradiographical, histochemical and radioimmunological study.

Authors:  H Tjälve
Journal:  Acta Physiol Scand Suppl       Date:  1971

5.  The occurrence of biogenic monoamines in the mammalian endocrine pancreas.

Authors:  L Cegrell
Journal:  Acta Physiol Scand Suppl       Date:  1968

6.  Uptake of DOPA and 5-HTP in pancreatic islets and parafollicular cells studied by combined autoradiographic and fluorescence microscopic techniques.

Authors:  H Tjälve; P Slanina
Journal:  Z Zellforsch Mikrosk Anat       Date:  1971

Review 7.  The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept.

Authors:  A G Pearse
Journal:  J Histochem Cytochem       Date:  1969-05       Impact factor: 2.479

8.  Insulin release and glucose changes induced by serotonin.

Authors:  J J Gagliardino; L M Zieher; F C Iturriza; R E Hernández; R R Rodríguez
Journal:  Horm Metab Res       Date:  1971-05       Impact factor: 2.936

9.  Monoamines in the pancreatic islets of the mouse. Subcellular localization of 5-hydroxytryptamine by electron microscopic autoradiography.

Authors:  R Ekholm; L E Ericson; I Lundquist
Journal:  Diabetologia       Date:  1971-10       Impact factor: 10.122
  9 in total
  1 in total

1.  Intracellular pancreatic B cell serotonin and the dynamics of insulin release.

Authors:  O M Pulido; S A Bencosme; M L de Bold; A J de Bold
Journal:  Diabetologia       Date:  1978-09       Impact factor: 10.122
  1 in total

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