Literature DB >> 3211703

Clinical effects and pharmacokinetics of articainic acid in one volunteer after intravenous administration.

G E Van Oss1, T B Vree, A M Baars, E F Termond, L H Booij.   

Abstract

Articainic acid, a major metabolite of articaine, was administered to a volunteer. Since the renewed interest in the utilization of articaine in epidural anaesthesia, it has been important to assess the clinical effects of this metabolite. It was noted that articainic acid had no effect on EEG, ECG, blood pressure and heart rate. Pharmacokinetic parameters are given.

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Year:  1988        PMID： 3211703     DOI： 10.1007/bf02219670

Source DB:  PubMed          Journal:  Pharm Weekbl Sci        ISSN： 0167-6555


  2 in total

1.  [Epidural anesthesia with carticaine in cesarean section. A comparison with bupivacaine].

Authors:  L Kaukinen; S Kaukinen; S Kärkkäinen
Journal:  Reg Anaesth       Date:  1986-07

2.  High-performance liquid chromatography and preliminary pharmacokinetics of articaine and its 2-carboxy metabolite in human serum and urine.

Authors:  T B Vree; A M Baars; G E van Oss; L H Booij
Journal:  J Chromatogr       Date:  1988-02-26
  2 in total
  3 in total

Review 1.  [Toxicology of local anesthetics. Clinical, therapeutic and pathological mechanisms].

Authors:  W Zink; B M Graf
Journal:  Anaesthesist       Date:  2003-12       Impact factor: 1.041

2.  Comparison of the effects and disposition kinetics of articaine and lidocaine in 20 patients undergoing intravenous regional anaesthesia during day case surgery.

Authors:  M A Simon; T B Vree; M J Gielen; L H Booij
Journal:  Pharm World Sci       Date:  1998-04

Review 3.  Clinical pharmacokinetics of articaine.

Authors:  R Oertel; R Rahn; W Kirch
Journal:  Clin Pharmacokinet       Date:  1997-12       Impact factor: 6.447
  3 in total

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