| Literature DB >> 32115627 |
Kyu Han Lee1, Birgit Nikolay2, Hossain M S Sazzad3,4, M Jahangir Hossain3,5, A K M Dawlat Khan3, Mahmudur Rahman3,6, Syed Moinuddin Satter3, Stuart T Nichol7, John D Klena7, Juliet R C Pulliam8, A Marm Kilpatrick9, Sharmin Sultana6, Sayma Afroj3, Peter Daszak10, Stephen Luby11, Simon Cauchemez2, Henrik Salje2, Emily S Gurley1.
Abstract
Contact patterns play a key role in disease transmission, and variation in contacts during the course of illness can influence transmission, particularly when accompanied by changes in host infectiousness. We used surveys among 1642 contacts of 94 Nipah virus case patients in Bangladesh to determine how contact patterns (physical and with bodily fluids) changed as disease progressed in severity. The number of contacts increased with severity and, for case patients who died, peaked on the day of death. Given transmission has only been observed among fatal cases of Nipah virus infection, our findings suggest that changes in contact patterns during illness contribute to risk of infection.Entities:
Keywords: Nipah virus; infectious disease transmission; social behavior
Mesh：
Year: 2020 PMID： 32115627 PMCID： PMC7336571 DOI： 10.1093/infdis/jiaa091
Source DB: PubMed Journal: J Infect Dis ISSN： 0022-1899 Impact factor: 5.226