Literature DB >> 321126

Effect of alloxan on rat pancreatic polypeptide (PP) cells.

F Sundler, R Håkanson, I Lundquist, L I Larsson.   

Abstract

Injection of alloxan caused an almost total disappearance of insulin cells in the rat pancreas. Planimetric analysis revealed a 50 per cent reduction of the mean islet volume. The number of immunoreactive pancreatic polypeptide (PP) cells per sectioned islet was significantly increased, and the PP cell volume per islet doubled. Assuming an unchanged number of islets, the results indicate an increase in total PP cell mass following alloxan administration.

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Year:  1977        PMID： 321126     DOI： 10.1007/bf00218695

Source DB:  PubMed          Journal:  Cell Tissue Res        ISSN： 0302-766X            Impact factor:   5.249


  9 in total

1.  Distribution and properties of glucagon immunoreactivity in the digestive tract of various mammals: an immunohistochemical and immunochemical study.

Authors:  L I Larsson; J Holst; R Håkanson; F Sundler
Journal:  Histochemistry       Date:  1975-09-29

2.  [INFLUENCE OF ALLOXAN ADMINSITRATION AND HYPOPHYSECTOMY ON THE PANCREATIC ISLETS OF THE RAT].

Authors:  K KOBAYASHI; Y TAKAHASHI; T JOHSHITA
Journal:  Arch Histol Jpn       Date:  1964-12

3.  Long-term changes of the alpha1 and alpha2 cells in the islets of Langerhans of rats with alloxan diabetes.

Authors:  B HELLMAN; B PETERSSON
Journal:  Endocrinology       Date:  1963-02       Impact factor: 4.736

4.  An improved glucose-oxidase method for determining blood, C.S.F. and urine glucose levels.

Authors:  V MARKS
Journal:  Clin Chim Acta       Date:  1959-05       Impact factor: 3.786

5.  Comparison of streptozotocin and alloxan-induced diabetes in the rat, including volumetric quantitation of the pancreatic islets.

Authors:  V Hoftiezer; A M Carpenter
Journal:  Diabetologia       Date:  1973-06       Impact factor: 10.122

6.  Immunohistochemical localization of human pancreatic polypeptide (HPP) to a population of islet cells.

Authors:  L I Larsson; F Sundler; R Håkanson
Journal:  Cell Tissue Res       Date:  1975       Impact factor: 5.249

7.  Pancreatic polypeptide - a postulated new hormone: identification of its cellular storage site by light and electron microscopic immunocytochemistry.

Authors:  L I Larsson; F Sundler; R Håkanson
Journal:  Diabetologia       Date:  1976-07       Impact factor: 10.122

8.  [Activity of somatostatin-containing cells of the Ilets of Langerhans in experimental diabetes].

Authors:  L Orci; D Baetens; C Rufener; M Amherdt; M Ravazzola; P Studer; F Malaisse-Lagae; R H Unger
Journal:  C R Acad Hebd Seances Acad Sci D       Date:  1975-12-15

9.  Hypertrophy and hyperplasia of somatostatin-containing D-cells in diabetes.

Authors:  L Orci; D Baetens; C Rufener; M Amherdt; M Ravazzola; P Studer; F Malaisse-Lagae; R H Unger
Journal:  Proc Natl Acad Sci U S A       Date:  1976-04       Impact factor: 11.205
  9 in total
  11 in total

1.  Two distinct types of islet abnormalities associated with endocrine pancreatic tumours.

Authors:  L I Larsson
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1977-11-25

2.  Virus-induced diabetes in mice: a quantitative evaluation of islet cell population by immunofluorescence technique.

Authors:  Y Stefan; F Malaisse-Lagae; J W Yoon; A L Notkins; L Orci
Journal:  Diabetologia       Date:  1978-11       Impact factor: 10.122

3.  An immunocytochemical and morphometric study of the rat pancreatic islets.

Authors:  A A Elayat; M M el-Naggar; M Tahir
Journal:  J Anat       Date:  1995-06       Impact factor: 2.610

4.  Regional distribution of pancreatic polypeptide cells in the 21-day fetal rat pancreas.

Authors:  J L Shevell; M R Schweisthal
Journal:  Experientia       Date:  1982-09-15

5.  Immunoreactivity of the endocrine pancreas. Evidence for the presence of cholecystokinin- pancreozymin within the A-cell.

Authors:  D Grube; V Maier; S Raptis; W Schlegel
Journal:  Histochemistry       Date:  1978-06-02

6.  Distribution, ontogeny and ultrastructure of pancreatic polypeptide (PP) cells in the pancreas and gut of the chicken.

Authors:  J Alumets; R Håkanson; F Sundler
Journal:  Cell Tissue Res       Date:  1978-12-12       Impact factor: 5.249

7.  Pancreatic beta cell mass PET imaging and quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in rodent models of diabetes.

Authors:  Tarun Singhal; Yu-Shin Ding; David Weinzimmer; Marc D Normandin; David Labaree; Jim Ropchan; Nabeel Nabulsi; Shu-fei Lin; Marc B Skaddan; Walter C Soeller; Yiyun Huang; Richard E Carson; Judith L Treadway; Gary W Cline
Journal:  Mol Imaging Biol       Date:  2010-09-08       Impact factor: 3.488

8.  Immunohistochemical identification and localization of pancreatic polypeptide cells in the pancreas and gastrointestinal tract of the human fetus and adult man.

Authors:  C Paulin; P M Dubois
Journal:  Cell Tissue Res       Date:  1978-04-17       Impact factor: 5.249

9.  Impaired response of pancreatic polypeptide to hypoglycaemia: an early sign of autonomic neuropathy in diabetics.

Authors:  T Krarup; T W Schwartz; J Hilsted; S Madsbad; O Verlaege; L Sestoft
Journal:  Br Med J       Date:  1979-12-15

10.  The duct-ligated pancreas transplant and its effect on the islet cellular composition of the host pancreas. A morphometric analysis.

Authors:  I B Brekke; J Alumets; F Sundler
Journal:  Cell Tissue Res       Date:  1983       Impact factor: 5.249
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