| Literature DB >> 32107514 |
A Xavier Kohll1, Philipp L Antkowiak1, Weida D Chen1, Bichlien H Nguyen2, Wendelin J Stark1, Luis Ceze3, Karin Strauss2, Robert N Grass1.
Abstract
Rapid aging tests (70 °C, 50% RH) of solid state DNA dried in the presence of various salt formulations, showed the strong stabilizing effect of calcium phosphate, calcium chloride and magnesium chloride, even at high DNA loadings (>20 wt%). A DNA-based digital information storage system utilizing the stabilizing effect of MgCl2 was tested by storing a DNA file, encoding 115 kB of digital data, and the successful readout of the file by sequencing after accelerated aging.Entities:
Year: 2020 PMID: 32107514 DOI: 10.1039/d0cc00222d
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222