Literature DB >> 32091449

Deprescribing Proton Pump Inhibitors in an Academic, Primary Care Clinic: Quality Improvement Project.

Naren Nallapeta1, Jessica L Reynolds2, Smita Bakhai3.   

Abstract

GOAL: The goal of this study was to reduce the percentage of inappropriately prescribed proton pump inhibitors (PPIs) in patients aged 50 and older from 80% (baseline) to 60% within 12 months in an academic, internal medicine clinic.
BACKGROUND: The use of PPIs has increased drastically worldwide. Internal medicine clinic patients had inappropriate use of PPIs for an average of 4 to 5 years. STUDY: A multidisciplinary quality improvement team used the Plan-Do-Study-Act Model of health care improvement and performed a root cause analysis to identify barriers to inappropriate use of PPIs. The outcome measure was the percentage of patients inappropriately prescribed PPI. Process measures were completion rates of PPI risk assessment and esophagogastroduodenoscopy. Interventions included the creation of customized electronic health record templates and education to providers and patients. Analysis was performed using monthly statistical process control charts.
RESULTS: The average rate of PPI discontinuation was 51.1% (n=92/180), which corresponds to 30.0% inappropriate PPI usage within 12 months. The mean PPI discontinuation rate in the 1-year prestudy, study and 6 months poststudy period was 2.0%, 32.0%, and 49.7%, respectively. The mean esophagogastroduodenoscopy completion rate was 49.8% from the baseline of <30%.
CONCLUSIONS: We achieved a statistically significant and sustainable reduction of inappropriate PPI use to 30% from the baseline rates of 80% and surpassed our goal within 12 months. This quality improvement was unique as no pharmacy personnel was utilized in this process. The multifaceted strategies in a safety-net internal medicine clinic resulted in successful deprescribing of PPI and can be replicated in other setting.

Entities:  

Mesh:

Substances:

Year:  2020        PMID: 32091449      PMCID: PMC7426248          DOI: 10.1097/MCG.0000000000001317

Source DB:  PubMed          Journal:  J Clin Gastroenterol        ISSN: 0192-0790            Impact factor:   3.174


  45 in total

1.  Inappropriate prescribing of proton pump inhibitors in older patients: effects of an educational strategy.

Authors:  Hanifat Hamzat; Hao Sun; Joanna C Ford; Joan Macleod; Roy L Soiza; Arduino A Mangoni
Journal:  Drugs Aging       Date:  2012-08-01       Impact factor: 3.923

2.  Meta-analysis: risk of fractures with acid-suppressing medication.

Authors:  Chun Shing Kwok; Jessica Ka-Yan Yeong; Yoon Kong Loke
Journal:  Bone       Date:  2010-12-23       Impact factor: 4.398

3.  Inappropriate prescribing of proton pump inhibitors in primary care.

Authors:  Bisanth Thushila Batuwitage; Jeremy G C Kingham; Nia Emma Morgan; Ruth Louise Bartlett
Journal:  Postgrad Med J       Date:  2007-01       Impact factor: 2.401

4.  Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline.

Authors:  Barbara Farrell; Kevin Pottie; Wade Thompson; Taline Boghossian; Lisa Pizzola; Farah Joy Rashid; Carlos Rojas-Fernandez; Kate Walsh; Vivian Welch; Paul Moayyedi
Journal:  Can Fam Physician       Date:  2017-05       Impact factor: 3.275

5.  Inappropriate prescribing of proton pump inhibitors in hospitalized patients.

Authors:  Mark Reid; Angela Keniston; J Christie Heller; Marshall Miller; Sofia Medvedev; Richard K Albert
Journal:  J Hosp Med       Date:  2011-12-21       Impact factor: 2.960

Review 6.  The Risks and Benefits of Long-term Use of Proton Pump Inhibitors: Expert Review and Best Practice Advice From the American Gastroenterological Association.

Authors:  Daniel E Freedberg; Lawrence S Kim; Yu-Xiao Yang
Journal:  Gastroenterology       Date:  2017-03       Impact factor: 22.682

7.  Proton pump inhibitor and histamine 2 receptor antagonist use and vitamin B12 deficiency.

Authors:  Jameson R Lam; Jennifer L Schneider; Wei Zhao; Douglas A Corley
Journal:  JAMA       Date:  2013-12-11       Impact factor: 56.272

8.  Four-year trends of inappropriate proton pump inhibitor use after hospital discharge.

Authors:  Frederick Leri; Mark Ayzenberg; Stephen J Voyce; Adam Klein; Leo Hartz; Raymond A Smego
Journal:  South Med J       Date:  2013-04       Impact factor: 0.954

Review 9.  Systematic review of the risk of enteric infection in patients taking acid suppression.

Authors:  Jennifer Leonard; John K Marshall; Paul Moayyedi
Journal:  Am J Gastroenterol       Date:  2007-05-17       Impact factor: 10.864

Review 10.  Pharmacology of proton pump inhibitors.

Authors:  Jai Moo Shin; George Sachs
Journal:  Curr Gastroenterol Rep       Date:  2008-12
View more
  3 in total

1.  Deprescribing Inappropriate Proton Pump Inhibitors in a Family Medicine Residency Practice Office.

Authors:  Andrew Lai; Amy Odom; Steven E Roskos; Julie P Phillips
Journal:  PRiMER       Date:  2021-11-02

2.  Patient Awareness of Reported Adverse Effects Associated with Proton Pump Inhibitors in a Medically Underserved Community.

Authors:  Brian White; Matthew Drew; John Gaughan; Sangita Phadtare
Journal:  Healthcare (Basel)       Date:  2020-11-19

3.  Effectiveness of a multi-faceted intervention to deprescribe proton pump inhibitors in primary care: protocol for a population-based, pragmatic, cluster-randomized controlled trial.

Authors:  Jérôme Nguyen-Soenen; Cédric Rat; Aurélie Gaultier; Solène Schirr-Bonnans; Philippe Tessier; Jean-Pascal Fournier
Journal:  BMC Health Serv Res       Date:  2022-02-17       Impact factor: 2.655

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.