Literature DB >> 34841218

Deprescribing Inappropriate Proton Pump Inhibitors in a Family Medicine Residency Practice Office.

Andrew Lai1, Amy Odom1, Steven E Roskos2, Julie P Phillips2.   

Abstract

INTRODUCTION: Proton pump inhibitors (PPIs) are often prescribed beyond their medically-approved duration of use. Long-term PPI use has been linked with numerous adverse effects and contributes to polypharmacy. This study sought to understand the effect of evidence-based education to resident and faculty physicians on deprescribing inappropriate PPIs. We hypothesized that this educational intervention would result in fewer inappropriate PPI prescriptions.
METHODS: We performed a chart review on all adult patients in a family medicine residency program practice, identifying those inappropriately taking PPIs. All physicians in the practice participated in an educational intervention regarding deprescribing inappropriate PPIs and were given frequent reminders to continue their deprescribing efforts. We reviewed charts at the end of the study to identify patients with successful deprescribing attempts.
RESULTS: Of the 187 patients prescribed inappropriate PPIs in the study, 100 remained on PPIs at the end of the study (46.6% success rate). There was a significant decrease in the number of patients inappropriately prescribed PPIs by each physician over the course of the study, from a mean of 17.0 (beginning) to 9.1 (end).
CONCLUSION: Physician education with reminders is an effective means of reducing the number of inappropriate PPIs prescribed in a family medicine residency practice. Future studies could investigate the effectiveness of educational interventions with other medication classes that are often prescribed inappropriately.
© 2021 by the Society of Teachers of Family Medicine.

Entities:  

Year:  2021        PMID: 34841218      PMCID: PMC8612589          DOI: 10.22454/PRiMER.2021.290175

Source DB:  PubMed          Journal:  PRiMER        ISSN: 2575-7873


  21 in total

1.  PPI use in patients commenced on clopidogrel: a retrospective cross-sectional evaluation.

Authors:  M Luinstra; M Naunton; G M Peterson; L Bereznicki
Journal:  J Clin Pharm Ther       Date:  2010-04       Impact factor: 2.512

2.  Risk of Clostridium difficile infection with acid suppressing drugs and antibiotics: meta-analysis.

Authors:  Chun Shing Kwok; Aaron Kobina Arthur; Chukwudubem Ifeanyichukwu Anibueze; Sonal Singh; Rodrigo Cavallazzi; Yoon Kong Loke
Journal:  Am J Gastroenterol       Date:  2012-04-24       Impact factor: 10.864

3.  Meta-analysis: proton pump inhibitor use and the risk of community-acquired pneumonia.

Authors:  J Johnstone; K Nerenberg; M Loeb
Journal:  Aliment Pharmacol Ther       Date:  2010-03-04       Impact factor: 8.171

Review 4.  Proton pump inhibitors linked to hypomagnesemia: a systematic review and meta-analysis of observational studies.

Authors:  Wisit Cheungpasitporn; Charat Thongprayoon; Wonngarm Kittanamongkolchai; Narat Srivali; Peter J Edmonds; Patompong Ungprasert; Oisin A O'Corragain; Sira Korpaisarn; Stephen B Erickson
Journal:  Ren Fail       Date:  2015-06-25       Impact factor: 2.606

5.  Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease.

Authors:  Benjamin Lazarus; Yuan Chen; Francis P Wilson; Yingying Sang; Alex R Chang; Josef Coresh; Morgan E Grams
Journal:  JAMA Intern Med       Date:  2016-02       Impact factor: 21.873

6.  Deprescribing in a family health team: a study of chronic proton pump inhibitor use.

Authors:  Kate Walsh; Debbie Kwan; Patricia Marr; Christine Papoushek; W Kirk Lyon
Journal:  J Prim Health Care       Date:  2016-06

7.  Proton-pump inhibitors and risk of fractures: an update meta-analysis.

Authors:  B Zhou; Y Huang; H Li; W Sun; J Liu
Journal:  Osteoporos Int       Date:  2016-01       Impact factor: 4.507

8.  Successful deprescribing of unnecessary proton pump inhibitors in a primary care clinic.

Authors:  Danielle R Odenthal; Ann M Philbrick; Ila M Harris
Journal:  J Am Pharm Assoc (2003)       Date:  2019-10-07

9.  Proton pump inhibitor and histamine 2 receptor antagonist use and vitamin B12 deficiency.

Authors:  Jameson R Lam; Jennifer L Schneider; Wei Zhao; Douglas A Corley
Journal:  JAMA       Date:  2013-12-11       Impact factor: 56.272

10.  Association of Proton Pump Inhibitors With Risk of Dementia: A Pharmacoepidemiological Claims Data Analysis.

Authors:  Willy Gomm; Klaus von Holt; Friederike Thomé; Karl Broich; Wolfgang Maier; Anne Fink; Gabriele Doblhammer; Britta Haenisch
Journal:  JAMA Neurol       Date:  2016-04       Impact factor: 18.302

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