Literature DB >> 32088191

The role and function of long non-coding RNAs in osteoarthritis.

Mitra Abbasifard1, Zahra Kamiab2, Zahra Bagheri-Hosseinabadi3, Iman Sadeghi4.   

Abstract

Osteoarthiritis (OA) is the most prevalent disease of articulating joints in human that frequently results in joint pain, movement limitations, inflammation, and progressive degradation of articular cartilage. The etiology of OA is not completely clear and there is no full treatment for this disease. Molecular investigations have revealed the involvement of non-coding RNAs such as Long non-coding RNAs (lncRNAs) in OA pathogenesis. LncRNAs play roles in multiple cellular and biological processes. Moreover, numerous lncRNAs are differentially expressed in human OA cartilage. In this review, we underlie the increasing evidence for the critical role of lncRNAs in OA pathogenesis reviewing the latest researches.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Joint disease; Long non-coding RNA; OA; Osteoarthritis; lncRNA

Year:  2020        PMID： 32088191     DOI： 10.1016/j.yexmp.2020.104407

Source DB:  PubMed          Journal:  Exp Mol Pathol        ISSN： 0014-4800            Impact factor:   3.362


  7 in total

1.  Effects of interleukin 1β on long noncoding RNA and mRNA expression profiles of human synovial fluid derived mesenchymal stem cells.

Authors:  Yang-Peng Sun; Yun-Yang Lu; Jianyu Chen; Jia-Hao Bao; Hong Zhang; Jia-Dong Sun; Wen-Ting Liao
Journal:  Sci Rep       Date:  2022-05-19       Impact factor: 4.996

2.  Osteopontin-induced lncRNA HOTAIR expression is involved in osteoarthritis by regulating cell proliferation.

Authors:  Quanzhi Liang; Ailijiang Asila; Yingjie Deng; Jun Liao; Zhenfeng Liu; Rui Fang
Journal:  BMC Geriatr       Date:  2021-01-14       Impact factor: 3.921

Review 3.  Circular RNAs in osteoarthritis: indispensable regulators and novel strategies in clinical implications.

Authors:  Wenchao Zhang; Lin Qi; Ruiqi Chen; Jieyu He; Zhongyue Liu; Wanchun Wang; Chao Tu; Zhihong Li
Journal:  Arthritis Res Ther       Date:  2021-01-12       Impact factor: 5.156

4.  Effect Of XBP1 Deficiency In Cartilage On The Regulatory Network Of LncRNA/circRNA-miRNA-mRNA.

Authors:  Xiaoli Li; Yuyou Yang; Li Liang; Mengtian Fan; Xingyue Li; Naibo Feng; Yiming Pan; Qiaoyan Tan; Qingbo Xu; Yangli Xie; Fengjin Guo
Journal:  Int J Biol Sci       Date:  2022-01-01       Impact factor: 6.580

Review 5.  Z-DNA-Containing Long Terminal Repeats of Human Endogenous Retrovirus Families Provide Alternative Promoters for Human Functional Genes.

Authors:  Du Hyeong Lee; Woo Hyeon Bae; Hongseok Ha; Eun Gyung Park; Yun Ju Lee; Woo Ryung Kim; Heui-Soo Kim
Journal:  Mol Cells       Date:  2022-08-05       Impact factor: 4.250

6.  Multi-omics molecular biomarkers and database of osteoarthritis.

Authors:  Jianhua Li; Xiaotian Yang; Qinjie Chu; Lingjuan Xie; Yuwen Ding; Xiaoxu Xu; Michael P Timko; Longjiang Fan
Journal:  Database (Oxford)       Date:  2022-07-05       Impact factor: 4.462

7.  Long Non-Coding RNA PVT1 and Its Target miRNA-146a as Potential Prognostic Biomarkers in Rheumatoid Arthritis Patients.

Authors:  Randa Erfan; Olfat G Shaker; Mahmoud A F Khalil; Yumn A Elsabagh; Azza M Ahmed; Abeer K Abu-El-Azayem; Mohamed S Gomaa; Asmaa Mohammed
Journal:  Life (Basel)       Date:  2021-12-10
  7 in total

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