Literature DB >> 32086831

ORMDL3 but not neighboring 17q21 gene LRRC3C is expressed in human lungs and lung cells of asthmatics.

Gyu Young Hur1,2, Alexa Pham1, Marina Miller1, Ning Weng1, Jingwen Hu1, Richard C Kurten3, David H Broide1.   

Abstract

Entities:  

Keywords:  LRRC3C; ORMDL3; asthma; chromosome 17q21; epithelium

Mesh：

Substances：

Year:  2020        PMID： 32086831      PMCID： PMC7387186          DOI： 10.1111/all.14243

Source DB:  PubMed          Journal:  Allergy        ISSN： 0105-4538            Impact factor:   13.146


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  9 in total

1.  Functional variants of 17q12-21 are associated with allergic asthma but not allergic rhinitis.

Authors:  Anand Kumar Andiappan; Yang Yie Sio; Bernett Lee; Bani Kaur Suri; Sri Anusha Matta; Josephine Lum; Shihui Foo; Geraldine Koh; Jianjun Liu; Francesca Zolezzi; Michael Poidinger; De Yun Wang; Olaf Rotzschke; Fook Tim Chew
Journal:  J Allergy Clin Immunol       Date:  2015-10-23       Impact factor: 10.793

2.  GSDMB/ORMDL3 variants contribute to asthma susceptibility and eosinophil-mediated bronchial hyperresponsiveness.

Authors:  Mi-Jin Kang; Ho-Sung Yu; Ju-Hee Seo; Hyung-Young Kim; Young-Ho Jung; Young-Joon Kim; Ha-Jung Kim; So-Yeon Lee; Soo-Jong Hong
Journal:  Hum Immunol       Date:  2012-06-23       Impact factor: 2.850

3.  Oroscomucoid like protein 3 (ORMDL3) transgenic mice have reduced levels of sphingolipids including sphingosine-1-phosphate and ceramide.

Authors:  Marina Miller; Peter Rosenthal; Andrew Beppu; Ruth Gordillo; David H Broide
Journal:  J Allergy Clin Immunol       Date:  2016-11-05       Impact factor: 10.793

Review 4.  Chromosome 17q21 Genes ORMDL3 and GSDMB in Asthma and Immune Diseases.

Authors:  Sudipta Das; Marina Miller; David H Broide
Journal:  Adv Immunol       Date:  2017-07-19       Impact factor: 3.543

5.  ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6.

Authors:  Marina Miller; Arvin B Tam; Jae Youn Cho; Taylor A Doherty; Alexa Pham; Naseem Khorram; Peter Rosenthal; James L Mueller; Hal M Hoffman; Maho Suzukawa; Maho Niwa; David H Broide
Journal:  Proc Natl Acad Sci U S A       Date:  2012-09-24       Impact factor: 11.205

6.  Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthma.

Authors:  V Berce; C E P Kozmus; U Potočnik
Journal:  Pharmacogenomics J       Date:  2012-09-18       Impact factor: 3.550

7.  ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma.

Authors:  Marina Miller; Peter Rosenthal; Andrew Beppu; James L Mueller; Hal M Hoffman; Arvin B Tam; Taylor A Doherty; Matthew D McGeough; Carla A Pena; Maho Suzukawa; Maho Niwa; David H Broide
Journal:  J Immunol       Date:  2014-03-12       Impact factor: 5.422

8.  Gene Expression-Genotype Analysis Implicates GSDMA, GSDMB, and LRRC3C as Contributors to Inflammatory Bowel Disease Susceptibility.

Authors:  Jan Söderman; Linda Berglind; Sven Almer
Journal:  Biomed Res Int       Date:  2015-09-21       Impact factor: 3.411

9.  Genome-wide association study to identify genetic determinants of severe asthma.

Authors:  Y I Wan; N R G Shrine; M Soler Artigas; L V Wain; J D Blakey; M F Moffatt; A Bush; K F Chung; W O C M Cookson; D P Strachan; L Heaney; B A H Al-Momani; A H Mansur; S Manney; N C Thomson; R Chaudhuri; C E Brightling; M Bafadhel; A Singapuri; R Niven; A Simpson; J W Holloway; P H Howarth; J Hui; A W Musk; A L James; M A Brown; S Baltic; M A R Ferreira; P J Thompson; M D Tobin; I Sayers; I P Hall
Journal:  Thorax       Date:  2012-05-05       Impact factor: 9.139
  9 in total
  4 in total

Review 1.  Advances and highlights in biomarkers of allergic diseases.

Authors:  Ismail Ogulur; Yagiz Pat; Ozge Ardicli; Elena Barletta; Lacin Cevhertas; Ruben Fernandez-Santamaria; Mengting Huang; Manal Bel Imam; Jana Koch; Siyuan Ma; Debbie J Maurer; Yasutaka Mitamura; Yaqi Peng; Urszula Radzikowska; Arturo O Rinaldi; Juan Rodriguez-Coira; Pattraporn Satitsuksanoa; Stephan R Schneider; Alexandra Wallimann; Damir Zhakparov; Reihane Ziadlou; Marie-Charlotte Brüggen; Willem van de Veen; Milena Sokolowska; Katja Baerenfaller; Luo Zhang; Mubeccel Akdis; Cezmi A Akdis
Journal:  Allergy       Date:  2021-09-27       Impact factor: 14.710

2.  Single-base editing of rs12603332 on chromosome 17q21 with a cytosine base editor regulates ORMDL3 and ATF6α expression.

Authors:  Ning Weng; Marina Miller; Alexa K Pham; Alexis C Komor; David H Broide
Journal:  Allergy       Date:  2021-09-24       Impact factor: 14.710

Review 3.  Current Understanding of Asthma Pathogenesis and Biomarkers.

Authors:  Nazia Habib; Muhammad Asghar Pasha; Dale D Tang
Journal:  Cells       Date:  2022-09-05       Impact factor: 7.666

Review 4.  Recent insights in the role of biomarkers in severe asthma management.

Authors:  Evangelia Fouka; Kalliopi Domvri; Foteini Gkakou; Maria Alevizaki; Paschalis Steiropoulos; Despoina Papakosta; Konstantinos Porpodis
Journal:  Front Med (Lausanne)       Date:  2022-09-26
  4 in total

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