Matthieu Bailly1, Frédérique Thibault2,3, Maxime Courtehoux3, Gilles Metrard2, Maria Joao Ribeiro3. 1. Nuclear Medicine Department, CHR ORLEANS, 14 Avenue de l'Hôpital, 45100, Orleans, France. matthieu.bailly@chr-orleans.fr. 2. Nuclear Medicine Department, CHR ORLEANS, 14 Avenue de l'Hôpital, 45100, Orleans, France. 3. Nuclear Medicine Department, CHRU TOURS, Tours, France.
Abstract
OBJECTIVES: Most of cardiac dedicated CZT-SPECT systems are not equipped with CT, whereas PET systems are. We evaluated the impact of AC correction on CZT-SPECT myocardial blood flow (MBF) and myocardial flow reserve (MFR) measurements. METHODS: 104 patients were included. SPECT data were acquired on cadmium zinc telluride (CZT)-based pinhole cardiac camera in listmode using a stress (250 ± 17 MBq)/rest (511 ± 23 MBq) 1-day Tc-99m-tetrofosmin protocol. Low-dose CT was acquired on another SPECT/CT camera in the same position. All analysis was performed using Corridor4DM. RESULTS: Stress and rest MBF were significantly lower when AC was applied (P < 0.001). For regional and global MFR, there was no significant difference between AC and NAC measurements (P > 0.25 at least). Mean global LV MFR was 2.43 ± 0.87 and 2.33 ± 0.89, respectively, for NAC and AC measurements. Using a threshold of 2, 86 patients (83%) remained classified as normal and abnormal regarding global LV MFR whether AC was applied or not. Mean difference between NAC and AC values for the 18 other patients was 0.3. CONCLUSION: AC correction does not significantly affect MFR measurement both in regional and global LV analyses.
OBJECTIVES: Most of cardiac dedicated CZT-SPECT systems are not equipped with CT, whereas PET systems are. We evaluated the impact of AC correction on CZT-SPECT myocardial blood flow (MBF) and myocardial flow reserve (MFR) measurements. METHODS: 104 patients were included. SPECT data were acquired on cadmium zinc telluride (CZT)-based pinhole cardiac camera in listmode using a stress (250 ± 17 MBq)/rest (511 ± 23 MBq) 1-day Tc-99m-tetrofosmin protocol. Low-dose CT was acquired on another SPECT/CT camera in the same position. All analysis was performed using Corridor4DM. RESULTS: Stress and rest MBF were significantly lower when AC was applied (P < 0.001). For regional and global MFR, there was no significant difference between AC and NAC measurements (P > 0.25 at least). Mean global LV MFR was 2.43 ± 0.87 and 2.33 ± 0.89, respectively, for NAC and AC measurements. Using a threshold of 2, 86 patients (83%) remained classified as normal and abnormal regarding global LV MFR whether AC was applied or not. Mean difference between NAC and AC values for the 18 other patients was 0.3. CONCLUSION: AC correction does not significantly affect MFR measurement both in regional and global LV analyses.
Authors: Andrea G Monroy-Gonzalez; Luis Eduardo Juarez-Orozco; Chunlei Han; Issi R Vedder; David Vállez García; Ronald Borra; Piotr J Slomka; Sergey V Nesterov; Juhani Knuuti; Riemer H J A Slart; Erick Alexanderson-Rosas Journal: J Nucl Cardiol Date: 2019-03-22 Impact factor: 5.952
Authors: Thais R Peclat; Ana Carolina do A H de Souza; Victor F Souza; Aline M K Nakamoto; Felipe M Neves; Izabella C R Silva; Ronaldo S L Lima Journal: J Nucl Cardiol Date: 2019-12-02 Impact factor: 5.952
Authors: Ana Carolina do A H de Souza; Hendrik J Harms; Laurel Martell; Courtney Bibbo; Meagan Harrington; Kyle Sullivan; Jon Hainer; Sharmila Dorbala; Ron Blankstein; Viviany R Taqueti; Marie Foley Kijewski; Mi-Ae Park; Alejandro Meretta; Christopher Breault; Nathaniel Roth; Alexis Poitrasson-Rivière; Prem Soman; Grant T Gullberg; Marcelo F Di Carli Journal: Circ Cardiovasc Imaging Date: 2022-06-08 Impact factor: 8.589
Authors: Mouaz H Al-Mallah; Timothy M Bateman; Kelley R Branch; Andrew Crean; Eric L Gingold; Randall C Thompson; Sarah E McKenney; Edward J Miller; Venkatesh L Murthy; Koen Nieman; Todd C Villines; Michael V Yester; Andrew J Einstein; John J Mahmarian Journal: J Nucl Cardiol Date: 2022-09-02 Impact factor: 3.872
Authors: Matthieu Bailly; Frédérique Thibault; Maxime Courtehoux; Gilles Metrard; Denis Angoulvant; Maria Joao Ribeiro Journal: Front Med (Lausanne) Date: 2021-06-04