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Literature DB >> 32077215

Linking m⁶ A to Wnt signaling.

Abstract

N6 -methyladenosine (m6 A) has emerged as a crucial molecular code to influence pluripotency and differentiation of diverse stem cells. A study in this issue now shows that, in intestinal stem cells, the m6 A reader protein YTHDF1 directs translational control of stemness in both m6 A- and Wnt-dependent manner [1].

Entities: Disease Gene

Mesh：

Year: 2020 PMID： 32077215 PMCID： PMC7132195 DOI： 10.15252/embr.202050097

Source DB: PubMed Journal: EMBO Rep ISSN： 1469-221X Impact factor: 8.807

10 in total

1. Linking m⁶ A to Wnt signaling.

Authors: Xiao-Min Liu; Shu-Bing Qian
Journal: EMBO Rep Date: 2020-02-20 Impact factor: 8.807

2. Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.

Authors: Shay Geula; Sharon Moshitch-Moshkovitz; Dan Dominissini; Abed AlFatah Mansour; Nitzan Kol; Mali Salmon-Divon; Vera Hershkovitz; Eyal Peer; Nofar Mor; Yair S Manor; Moshe Shay Ben-Haim; Eran Eyal; Sharon Yunger; Yishay Pinto; Diego Adhemar Jaitin; Sergey Viukov; Yoach Rais; Vladislav Krupalnik; Elad Chomsky; Mirie Zerbib; Itay Maza; Yoav Rechavi; Rada Massarwa; Suhair Hanna; Ido Amit; Erez Y Levanon; Ninette Amariglio; Noam Stern-Ginossar; Noa Novershtern; Gideon Rechavi; Jacob H Hanna
Journal: Science Date: 2015-01-01 Impact factor: 47.728

3. N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells.

Authors: Yang Wang; Yue Li; Julia I Toth; Matthew D Petroski; Zhaolei Zhang; Jing Crystal Zhao
Journal: Nat Cell Biol Date: 2014-01-07 Impact factor: 28.824

4. YTHDF1-mediated translation amplifies Wnt-driven intestinal stemness.

Authors: Bing Han; Sujun Yan; Saisai Wei; Jie Xiang; Kangli Liu; Zhanghui Chen; Rongpan Bai; Jinghao Sheng; Zhengping Xu; Xiangwei Gao
Journal: EMBO Rep Date: 2020-02-17 Impact factor: 8.807

Review 5. Wnt Signaling in 3D: Recent Advances in the Applications of Intestinal Organoids.

Authors: Alessandra Merenda; Nicola Fenderico; Madelon M Maurice
Journal: Trends Cell Biol Date: 2019-11-09 Impact factor: 20.808

Review 6. RNA modifications modulate gene expression during development.

Authors: Michaela Frye; Bryan T Harada; Mikaela Behm; Chuan He
Journal: Science Date: 2018-09-28 Impact factor: 47.728

Review 7. The Intestinal Stem Cell Niche: Homeostasis and Adaptations.

Authors: António J M Santos; Yuan-Hung Lo; Amanda T Mah; Calvin J Kuo
Journal: Trends Cell Biol Date: 2018-09-05 Impact factor: 21.167

8. m⁶A facilitates hippocampus-dependent learning and memory through YTHDF1.

Authors: Hailing Shi; Xuliang Zhang; Yi-Lan Weng; Hongjun Song; Chuan He; Tao Zhou; Zongyang Lu; Yajing Liu; Zhike Lu; Jianan Li; Piliang Hao; Yu Zhang; Feng Zhang; You Wu; Jary Y Delgado; Yijing Su; Meera J Patel; Xiaohua Cao; Bin Shen; Xingxu Huang; Guo-Li Ming; Xiaoxi Zhuang
Journal: Nature Date: 2018-10-31 Impact factor: 49.962

9. Anti-tumour immunity controlled through mRNA m⁶A methylation and YTHDF1 in dendritic cells.

Authors: Dali Han; Jun Liu; Chuanyuan Chen; Lihui Dong; Yi Liu; Renbao Chang; Xiaona Huang; Yuanyuan Liu; Jianying Wang; Urszula Dougherty; Marc B Bissonnette; Bin Shen; Ralph R Weichselbaum; Meng Michelle Xu; Chuan He
Journal: Nature Date: 2019-02-06 Impact factor: 49.962

10. YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression.

Authors: Yulin Shi; Songqing Fan; Mengge Wu; Zhixiang Zuo; Xingyang Li; Liping Jiang; Qiushuo Shen; Peifang Xu; Lin Zeng; Yongchun Zhou; Yunchao Huang; Zuozhang Yang; Jumin Zhou; Jing Gao; Hu Zhou; Shuhua Xu; Hongbin Ji; Peng Shi; Dong-Dong Wu; Cuiping Yang; Yongbin Chen
Journal: Nat Commun Date: 2019-10-25 Impact factor: 14.919

10 in total

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