Literature DB >> 3207655

Drugs, including alcohol, that act as risk factors for cataract, and possible protection against cataract by aspirin-like analgesics and cyclopenthiazide.

J J Harding1, R van Heyningen.   

Abstract

A case-control study of cataract in Oxfordshire explored the risks and benefits associated with a variety of drugs. Steroids including the diuretic spironolactone, nifedipine, heavy smoking, and beer drinking were associated with a raised risk. On the other hand aspirin-like analgesics (paracetamol, ibuprofen, aspirin, etc. appeared to protect against cataract. Cyclopenthiazide appeared to provide a similar protection.

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Year:  1988        PMID: 3207655      PMCID: PMC1041596          DOI: 10.1136/bjo.72.11.809

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  21 in total

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Journal:  Horm Metab Res       Date:  1977-05       Impact factor: 2.936

4.  A case-control study of cataract in Oxfordshire: some risk factors.

Authors:  R van Heyningen; J J Harding
Journal:  Br J Ophthalmol       Date:  1988-11       Impact factor: 4.638

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Journal:  Lancet       Date:  1981-02-07       Impact factor: 79.321

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Journal:  Can J Ophthalmol       Date:  1982-06       Impact factor: 1.882

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Journal:  Diabetes       Date:  1978-12       Impact factor: 9.461

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Journal:  J Clin Invest       Date:  1984-11       Impact factor: 14.808

10.  Formation of covalent adducts between cortisol and 16 alpha-hydroxyestrone and protein: possible role in the pathogenesis of cortisol toxicity and systemic lupus erythematosus.

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Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

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  22 in total

1.  Lens opacity in patients with hypercholesterolemia and ischaemic heart disease. Electronic lens opacity measurements.

Authors:  M Leino; K Pyörälä; S Lehto; A Rantala
Journal:  Doc Ophthalmol       Date:  1992       Impact factor: 2.379

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Authors:  H R Taylor; B Muñoz
Journal:  Br J Ophthalmol       Date:  1989-07       Impact factor: 4.638

3.  Influence of the Time of Intravenous Administration of Paracetamol on its Pharmacokinetics and Ocular Disposition in Rabbits.

Authors:  Agnieszka Karbownik; Agnieszka Bienert; Włodzimierz Płotek; Tomasz Grabowski; Magdalena Cerbin-Koczorowska; Anna Wolc; Edmund Grześkowiak
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2017-06       Impact factor: 2.441

4.  Risk factors associated with age-related nuclear and cortical cataract : a case-control study in the Age-Related Eye Disease Study, AREDS Report No. 5.

Authors: 
Journal:  Ophthalmology       Date:  2001-08       Impact factor: 12.079

5.  A case-control study of cataract in Oxfordshire: some risk factors.

Authors:  R van Heyningen; J J Harding
Journal:  Br J Ophthalmol       Date:  1988-11       Impact factor: 4.638

Review 6.  A comparative review of the adverse effects of calcium antagonists.

Authors:  H T Dougall; J McLay
Journal:  Drug Saf       Date:  1996-08       Impact factor: 5.606

Review 7.  Cigarettes and cataract: cadmium or a lack of vitamin C?

Authors:  J J Harding
Journal:  Br J Ophthalmol       Date:  1995-03       Impact factor: 4.638

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Authors:  C Silagy
Journal:  Drugs Aging       Date:  1993 Jul-Aug       Impact factor: 3.923

9.  Effect of cigarette smoking on copper, lead, and cadmium accumulation in human lens.

Authors:  O Cekic
Journal:  Br J Ophthalmol       Date:  1998-02       Impact factor: 4.638

10.  Does aspirin affect the rate of cataract formation? Cross-sectional results during a randomised double-blind placebo controlled trial to prevent serious vascular events. UK-TIA Study Group.

Authors: 
Journal:  Br J Ophthalmol       Date:  1992-05       Impact factor: 4.638

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