Merrill Thomas1, Krishna K Patel1, Kensey Gosch2, Clementine Labrosciano3, Carlos Mena-Hurtado4, Robert Fitridge5, John A Spertus1, Kim G Smolderen6. 1. University of Missouri-Kansas City School of Medicine, 2411 Holmes Street, Kansas City, MO 64108, United States of America; Saint Luke's Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, United States of America. 2. Saint Luke's Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, United States of America. 3. Discipline of Medicine, University of Adelaide, Adelaide, South Australia, Australia; Translational Vascular Function Research, Basil Hetzel Institute for Translational Research, Woodville, South Australia, Australia. 4. Yale New Haven Hospital, Yale University, New Haven, CT, United States of America. 5. Discipline of Surgery, Adelaide Medical School, The University of Adelaide, Adelaide, South Australia, Australia. 6. University of Missouri-Kansas City School of Medicine, 2411 Holmes Street, Kansas City, MO 64108, United States of America; Saint Luke's Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, United States of America; Yale New Haven Hospital, Yale University, New Haven, CT, United States of America. Electronic address: kim.smolderen@yale.edu.
Abstract
OBJECTIVES: To document the prevalence and patient profiles of mental health concerns in patients with peripheral artery disease (PAD) seen in the vascular specialty setting. METHODS: In a cohort of 1275 patients presenting to 16 specialty clinics with new or worsening claudication, symptoms of depression, anxiety, and stress were quantified in 957 patients. The Patient Health Questionnaire-8 (PHQ-8), Generalized Anxiety Disorder scale-2 (GAD-2), and Perceived Stress Scale-4 (PSS-4) were assessed for mental health concerns at the initial PAD work-up and repeated 12 months later. PHQ-8 ≥ 10, GAD-2 ≥ 3 and PSS-4 ≥ 6 were considered significant for depression, anxiety and stress respectively. Patient characteristics were compared in groups divided by presence of 0, 1, 2 or all 3 mental health concerns. RESULTS: On the initial office visit, 336/957 (35%) of patients had high levels of at least one of the three mental health concerns. At both baseline and 12 months, high levels of perceived stress were most often reported (28.7% and 17.5% respectively), followed by symptoms of depression (14.1% and 8.9%) and then anxiety (8.3% and 5.7%). Patients with mental health concerns were more often female, younger, had more financial strain, less social support, and worse perceived health status. CONCLUSIONS: Mental health concerns, particularly stress, are highly prevalent in patients with PAD, especially upon first presenting with new or worsening symptoms. The role of stress and how it may impede successful PAD management and impact subsequent outcomes warrants further investigation.
OBJECTIVES: To document the prevalence and patient profiles of mental health concerns in patients with peripheral artery disease (PAD) seen in the vascular specialty setting. METHODS: In a cohort of 1275 patients presenting to 16 specialty clinics with new or worsening claudication, symptoms of depression, anxiety, and stress were quantified in 957 patients. The Patient Health Questionnaire-8 (PHQ-8), Generalized Anxiety Disorder scale-2 (GAD-2), and Perceived Stress Scale-4 (PSS-4) were assessed for mental health concerns at the initial PAD work-up and repeated 12 months later. PHQ-8 ≥ 10, GAD-2 ≥ 3 and PSS-4 ≥ 6 were considered significant for depression, anxiety and stress respectively. Patient characteristics were compared in groups divided by presence of 0, 1, 2 or all 3 mental health concerns. RESULTS: On the initial office visit, 336/957 (35%) of patients had high levels of at least one of the three mental health concerns. At both baseline and 12 months, high levels of perceived stress were most often reported (28.7% and 17.5% respectively), followed by symptoms of depression (14.1% and 8.9%) and then anxiety (8.3% and 5.7%). Patients with mental health concerns were more often female, younger, had more financial strain, less social support, and worse perceived health status. CONCLUSIONS: Mental health concerns, particularly stress, are highly prevalent in patients with PAD, especially upon first presenting with new or worsening symptoms. The role of stress and how it may impede successful PAD management and impact subsequent outcomes warrants further investigation.
Authors: Ali O Malik; Kensey Gosch; Merrill B Thomas; Carlos Mena-Hurtado; William Hiatt; Herbert D Aronow; Phillip G Jones; Jeremy Provance; Clementine Labrosciano; Qurat-Ul-Ain Jelani; John A Spertus; Kim G Smolderen Journal: J Psychosom Res Date: 2020-11-24 Impact factor: 3.006
Authors: Muhammad Mainuddin Patwary; Mondira Bardhan; Asma Safia Disha; Md Pervez Kabir; Md Riad Hossain; Md Ashraful Alam; Md Zahidul Haque; Sharif Mutasim Billah; Matthew H E M Browning; Russell Kabir; Sarya Swed; Sheikh Shoib Journal: Int J Environ Res Public Health Date: 2022-06-02 Impact factor: 4.614